Journals / Atatürk Üniversitesi Tıp Dergisi (Y. A. The Eurasian Journal of Medicine) / 2000 / Cilt: 32 - Sayı: 4

Serum sex hormon levels in the male patients with active Behcet's disease

Erkek aktif Behçet hastalarında serum seks hormon düzeyleri

Pages
149–151
Publication Date
2022-10-10
DOI
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⚡ TL;DR(Too Long; Didn't Read)

We found that dihydrepiandrosterone sulphate, (DHEAS), total testosterone and androstenedione levels in patients with clinically active BD, were not significantly higher than control group.

📌 3 Key Takeaways

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Objective & Hypothesis:Behcet's disease (BD) is a systemic vasculitis of unknown aetiology characteristically affecting venules.
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Key Findings & Data:Serum sex hormones were measured in 16 male patients with active BD, and 20 male healthy volunteers.
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Conclusion & Impact:We found that dihydrepiandrosterone sulphate, (DHEAS), total testosterone and androstenedione levels in patients with clinically active BD, were not significantly higher than control group.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Behcet's disease (BD) is a systemic vasculitis of unknown aetiology characteristically affecting venules. Onset is typically in young adults with recurrent oral and genital ulceration, uveitis, skin manifestations, arthritis, neurological involvement, acneiform lesions and a tendency to thrombosis. BD especially has a more severe course in men. This finding may be regarded as evidence that a contribution of sex hormones to the aetiopathogenesis of BD seems likely. We investigated which effect of sex hormones on the pathogenesis of BD. Serum sex hormones were measured in 16 male patients with active BD, and 20 male healthy volunteers. We found that dihydrepiandrosterone sulphate, (DHEAS), total testosterone and androstenedione levels in patients with clinically active BD, were not significantly higher than control group.

Özet

Behçet hastalığı, mukozalar ve deri tutulumu başta olmak üzere, oral aft, genital ülserasyonlar, eklem tutulumu ve nörolojik tutulumun görüldüğü etiopatogenezi tam olarak bilinmeyen, kronik bir hastalıktır. Erkek hastalarda daha ağır seyretmesi, hastalığın bulgularından biri olan akneiform lezyonların görülmesi bu hastalığın patogenezinde seks hormonlarının rolünün olabileceğini akla getirmektedir. Biz seks hormonlarının hastalık patogenezindeki etkisini incelemeyi amaçladık, Bunun için 16 aktif erkek Behçet hastasında ve 20 sağlıklı kişide androjenik etkili serum seks hormon düzeylerini ölçerek iki grubu karşılaştırdık. Her iki grupta, dehidroepiandrosteron sülfat (DHEAS), total testesteron ve androstenedion düzeyleri arasında istatistiksel anlamlı farklılık saptanmadı.

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Cite This Article

ODABAŞ, A. R., ÇAPOĞLU, İ., SELÇUK, Y., ÇETİNKAYA, R., KARAKUZU, A. (2022). Serum sex hormon levels in the male patients with active Behcet's disease. Atatürk Üniversitesi Tıp Dergisi (Y. A. The Eurasian Journal of Medicine), Cilt: 32 - Sayı: 4, 149–151. https://ajindex.com/articles/454874

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References (1)

  1. Apaydin KC, Duranoglu Y, Ozgurel Y, Saka O. Serum prolactin levels in Behçet's disease. Jpn J Ophthalmol 2000;44:442-445 2.Eglin RP, Lehner T, Subak-Sharpe JH. Detection of RNA complementary to herpes-simplex virus in mononuclear cells from patients with Behçet's syndrome and recurrent oral ulcers. Lancet1982;2:1356-1361 3.Yazici H, Fresko I, Hamuryudan V, Mat C, Melikoglu M, Ozyazgan Y, Tuzun Y, Yurdakul S. Behçet's syndrome. The Cerrahpasa experience. Members of the Behçet's Syndrome Research Centre.Adv Exp Med Biol 1999;455:135-140