Journals / Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi / 2012 / Cilt: 22 - Sayı: 1

The correlation of blood tests with DMFT scores microbiologic counts and buffer capacity of saliva

Kan testleri ile DMFT skorları, mikrobiyolojik sayım ve tükürüğün tamponlama kapasitesi arasındaki korelasyon

Pages
14–19
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results showed that in the presence of high s. mutans and lactobacilli and low buffer capacity, there was a statistically significant correlation between DMFT scores and Il-8, IgA, IgD, CD4, CD19 and eosinophiles.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Over the last decade, there is an increasing interest in possible associations between oral and systemic diseases since the bacteria and/or their products are known to invade the systemic circulation.
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Key Findings & Data:In this study, the possible correlation of DMFT (decayed, missing, filled teeth) scores, with microbiologic counts, the buffer capacity of saliva and certain blood parameters such as blood cells counts and inflammatory cytokins has been analyzed in 152 patients with healthy periodontium.
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Conclusion & Impact:The results showed that in the presence of high s. mutans and lactobacilli and low buffer capacity, there was a statistically significant correlation between DMFT scores and Il-8, IgA, IgD, CD4, CD19 and eosinophiles.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Over the last decade, there is an increasing interest in possible associations between oral and systemic diseases since the bacteria and/or their products are known to invade the systemic circulation. Besides the effects of carious tissue on other teeth, severe caries may have some consequences on the general health such as growth and weight gain retardation, upregulation of some systemic parameters of inflammation. In this study, the possible correlation of DMFT (decayed, missing, filled teeth) scores, with microbiologic counts, the buffer capacity of saliva and certain blood parameters such as blood cells counts and inflammatory cytokins has been analyzed in 152 patients with healthy periodontium. The results showed that in the presence of high s. mutans and lactobacilli and low buffer capacity, there was a statistically significant correlation between DMFT scores and Il-8, IgA, IgD, CD4, CD19 and eosinophiles. The results have indicated that also dental caries should be included in the perspective of oral health and systemic health, and they suggest that the dental and medical professions should develop even closer ties in the future.

Özet

Son zamanlarda sirkülasyona katılan oral bakteriler ve bakteri ürünleri ile sistemik hastalıklar arasında ilişki kurulmaya çalışılmaktadır. Çürük lezyonu dişte oluşturduğu harabiyet dışında, ilerlediği durumlarda da genel sağlıkla ilgili büyüme, kilo alımında problem, bazı sistemik inflamatuar parametrelerde artışa neden olmaktadır. Bu çalışmada DMFT (çürük, eksik, dolgulu diş) skorları, mikrobiyolojik sayım, tükürüğün tamponlama kapasitesi, kan hücreleri, inflamatuar hücreler gibi belirli kan hücrelerine ait parametreler, sağlıklı periodonsiyuma sahip 152 hastada analiz edilmiştir. Yüksek oranlarda S. Mutans ve Lactobacilli, düşük tamponlama kapasitesi varlığında DMFT skorları ile IL8, Ig A, Ig D, CD4, CD 19 ve eozinofil değerleri arasında istatistiksel olarak belirgin bir korelasyon elde edilmiştir. Sonuçlar oral sağlığın sistemik sağlık çerçevesinde değerlendirilmesi gerektiğini, diş hekimleri ile tıp doktorları arasında hasta ile ilgili iletişimin olması gerektiğini göstermektedir.

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Cite This Article

KELEŞ, B., HAYTAÇ, C., ÖZTURAN, S., ÖZTUNÇ, H. (2022). The correlation of blood tests with DMFT scores microbiologic counts and buffer capacity of saliva. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, Cilt: 22 - Sayı: 1, 14–19. https://ajindex.com/articles/452478

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References (16)

  1. Newman HN. Focal sepsis- modern concept. J Ir Dent Assoc 1968;14:53-63
  2. Newman HN. Focal infection. J Dent Res 1996;75:1912-9
  3. Li X, Kolltveit K, Tronstad L, Olsen I. Systemic diseases caused by oral infection. Clin Microbiol Rev 2000;13:547-558
  4. Gibbs RS. The relationship between infections and adverse pregnancy outcomes:an overview. Ann Periodontol 2001;6:153-63. 5. de Soet JJ, Schriks MCM, Kratz E, Poland DCW, van Dijk W, van Amerongen WE. Dental caries related to plasma IgG and alpha1 – acid glycoprotein. Caries Res 2003; 37:79-84
  5. Yoshihara A, Hanada, Miyazaki H. Association between serum albumin and root caries in community-dwelling older adults. J Dent Res 2003;82:218-222
  6. Hahn CL, Best AM, Tew JG. Comparison of Type 1 and Type 2 Cytokine production by mononuclear cells cultured with Streptococcus mutans and selected other caries bacteria. J Endodon 2004;30:333-8
  7. Izumi T, Kobayashi I, Okamura K, Matsuo K, Kiyoshima T, Ishibashi Y, Inoue H, Sakai H. An immunohistochemical study of HLA-DR and alpha 1-antichymotrypsin-positive cells in the pulp of human non-carious and carious teeth. Arch Oral Biol 1996;41:627-30
  8. Hahn CL, Best AM, Tew JG. Cytokine Induction by Streptococcus mutans and pulpal pathogenesis. Infect Immun 2000;68:6785-89
  9. Baum LJ. Dental pulp conditions in relation to carious lesions. Int Dent J 1970;20:309
  10. Ivanyi L, Lehner T. The relationship between caries index and stimulation of lymphocytes by Streptococcus mutans in mothers and their neonates. Arch Oral Biol 1978;23:851-6
  11. Izumi T, Kobayashi I, Okamura K, Sakai H. Immunohistochemical study on the immunocompetent cells of the pulp in human noncarious and carious teeth. Arch Oral Biol 1995;40:609-14
  12. Moore MA, Gregory RL, Switalski LM, Hakki ZW, Gfell LE, Kowolik MJ. Differential activation of human neutrophils by Streptococcus mutans isolates from root surface lesions and caries-free and caries-active subjects. Oral Microbiol Immunol 1998;13:41-6
  13. Jontell M, Okiji T, Dahlgren U, Bergenholtz G. Immun defense mechanisms of the dental pulp. Crit Rev Oral Biol Med 1998;9:179-200
  14. Pezelji-Ribaric S, Anic I, Brekalo I, Miletic I, Hasan M, Simunovic-Soskic M. Detection of tumor necrosis factor alpha in normal and inflamed human dental pulps. Arch Med Res 2002;33:482-4
  15. Nakanishi T, Matsuo T, Ebusi S. Quantitative analysis of immunoglobulins and inflammatory factors in human pulpal blood from exposed pulps. J Endod 1995;21:131-6
  16. Chall