SavedAdd your journal

Journals / Arşiv Kaynak Tarama Dergisi / 2018 / Cilt: 27 - Sayı: 2

Nanoparticle Applications in Mammalian Tumor and Normal Cell Lines

Memeli Tümör ve Normal Hücre Hatlarında Nanopartikül Uygulamaları

Orhan YILMAZ
Yeşim DAĞLIOĞLU
Huri Özkan YILMAZ
Pages
136–174
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, recent studies on nanoparticle applications in mammalian normal and tumor cell lines were discussed..

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In the 2000s, as a result of the rapid progress of nanotechnology, nanomedicine emerged as a new science and technology field, and the most deadly disease of the 21st century, cancer remedies were sought.
📊
Key Findings & Data:In recent years, by combining cell line applications and nanotechnology, it is aimed to develop targeted cancer treatments with new generation drugs produced by using nanoparticles which kill tumor cells and which do not damage healthy (normal) cells.
💡
Conclusion & Impact:In this review, recent studies on nanoparticle applications in mammalian normal and tumor cell lines were discussed..
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In the 2000s, as a result of the rapid progress of nanotechnology, nanomedicine emerged as a new science and technology field, and the most deadly disease of the 21st century, cancer remedies were sought. In recent years, by combining cell line applications and nanotechnology, it is aimed to develop targeted cancer treatments with new generation drugs produced by using nanoparticles which kill tumor cells and which do not damage healthy (normal) cells. In this review, recent studies on nanoparticle applications in mammalian normal and tumor cell lines were discussed..

Özet

İki binli yıllarda nanoteknolojinin hızla ilerlemesi sonucu, nano tıp yeni bir bilim dalı ve teknoloji alanı olarak ortaya çıkmış ve 21. yüzyılın en ölümcül hastalığı olan kansere çareler aranmıştır. Son yıllarda, hücre hattı uygulamaları ile nanoteknoloji biliminin birleşmesiyle tümör hücrelerini öldüren, sağlıklı (normal) hücrelere hasar vermeyen nanopartiküllerle üretilen yeni nesil ilaçlarla hedefe yönelik kanser tedavilerinin geliştirilmesi amaçlanmıştır. Bu derlemede, memeli tümör ve normal hücre hatlarında nanopartikül uygulamaları ile ilgili son yıllarda yapılan çalışmalar ele alınmıştır

🔖

Cite This Article

YILMAZ, O., DAĞLIOĞLU, Y., YILMAZ, H. Ö. (2022). Nanoparticle Applications in Mammalian Tumor and Normal Cell Lines. Arşiv Kaynak Tarama Dergisi, Cilt: 27 - Sayı: 2, 136–174. https://ajindex.com/articles/449165

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Paz-Elizur T, Sevilya Z, Leitner-Dagan Y, Elinger D, Roisman CL, Livneh Z. DNA repair of oxidative DNA damage in human carcinogenesis: potential application for cancer risk assessment and prevention. Cancer Lett. 2008;266:60-72.
  2. Stein A, Melde BJ, Schroden RC. Hybrid inorganic–organic mesoporous silicates—nanoscopic reactors coming of age. Adv Mater. 2000;12:1403-19.
  3. Han YJ, Stucky GD, Butler A. Mesoporous silicate sequestration and release of proteins. J Am Chem Soc. 1999;121:9897-8.
  4. Lu J, Liong M, Zink JI, Tamanoi F. Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs. Small. 2007;3:1341–6.
  5. Lu F, Doane TL, Zhu JJ, Burda C. Gold nanoparticles for diagnostic sensing and therapy. Inorganica Chim Acta. 2012;393:142-153
  6. Doane TL, Burda C. The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy. Chem Soc Rev. 2012;41:2885–2911.
  7. Garcia ME, Baker LA, Crooks RM. Preparation and characterization of dendrimer-gold colloid nanocomposites. Anal Chem. 1999;71:256-8.
  8. Cheng Y, Samia AC, Meyers JD, Panagopoulos I, Fei BW, Burda C. Highly efficient drug delivery with gold nanoparticle vectors for in vivo photodynamic therapy of cancer. J Am Chem Soc.2008;130:10643-7.
  9. El-Sayed IH, Huang XH, El-Sayed MA. Surface plasmon resonance scattering and absorption of anti-EGFR antibody conjugated gold nanoparticles in cancer diagnostics: applications in oral cancer. Nano Lett. 2005;5:829-34.
  10. Zhang JD, Oyama M. A hydrogen peroxide sensor based on the peroxidase activity of hemoglobin immobilized on gold nanoparticles-modified ITO electrode. Electrochim Acta. 2004;50:85-90
  11. Jia JB, Wang BQ, Wu AG, Cheng GJ, Li Z, Dong SJ. A method to construct a third-generation horseradish peroxidase biosensor: self-assembling gold nanoparticles to three-dimensional sol−gel network. Anal Chem. 2002;74:2217-23.
  12. Smith BD, Dave N, Huang PJJ, Liu JW. Assembly of DNA-functionalized gold nanoparticles with gaps and overhangs in linker DNA. J Phys Chem. 2011;115:7851-7.
  13. Giljohann DA, Seferos DS, Patel PC, Millstone JE, Rosi NL, Mirkin CA. Oligonucleotide loading determines cellular uptake of DNA-modified gold nanoparticles. Nano Lett. 2007;7:3818-21
  14. Lee JS, Han MS, Mirkin CA, Colorimetric detection of mercuric ion (Hg2+) in aqueous media using DNA‐functionalized gold nanoparticles. Angewandte Chemie. 2007;119:4171-4.
  15. Rosi, NL, Giljohann DA, Thaxton CS, Lytton-Jean AK, Han MS, Mirkin C.A. Oligonucleotide-modified gold nanoparticles for intracellul