Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 5

Evaluation of the effect of chronic smoking habit on corneal endothelial cells, central corneal thickness and dry eye tests

Pages
888–893
Publication Date
2022-10-12
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

TBUT and Schirmer tests were significantly decreased in all groups.Conclusion: It was found that as the number of pack-year increased, CD and HEX values decreased and AVG and CV values increased.Dry eye tests were affected in a shorter period of time, while CCT was affected in a longer period of time than the time required forCD, HEX, AVG and CV parameters to be affected.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The aim of our study was to evaluate the effects of chronic smoking habit on corneal endothelial cells, central corneal thickness,and dry eye tests.Material and Methods: A total of 160 eyes of 160 chronic smokers and 160 eyes of 160 control cases were included in the study.
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Key Findings & Data:Thesmokers were grouped into 4 groups according to pack-year smoking as follows: 0-10, 10-20, 20-30, >30.
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Conclusion & Impact:TBUT and Schirmer tests were significantly decreased in all groups.Conclusion: It was found that as the number of pack-year increased, CD and HEX values decreased and AVG and CV values increased.Dry eye tests were affected in a shorter period of time, while CCT was affected in a longer period of time than the time required forCD, HEX, AVG and CV parameters to be affected.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of our study was to evaluate the effects of chronic smoking habit on corneal endothelial cells, central corneal thickness,and dry eye tests.Material and Methods: A total of 160 eyes of 160 chronic smokers and 160 eyes of 160 control cases were included in the study. Thesmokers were grouped into 4 groups according to pack-year smoking as follows: 0-10, 10-20, 20-30, >30. Endothelial cell density(CD), average cell size (AVG), percentage of hexagonal cell (HEX), and coefficient of variation (CV), central corneal thickness (CCT)were measured using a specular microscope. The Tear Break-Up Time (TUBT) and Schirmer tests were performed.Results: In Group 1 and Group 2, there was no significant difference between the smoker and the control groups in terms of CD, AVG,HEX and CV. In Group 3 and Group 4, there was a significant decrease in CD and HEX values, while there was a significant increasein AVG and CV values. CCT values were not significantly different in the Groups 1,2 and 3, whereas there was a significant decreasein the Group 4. TBUT and Schirmer tests were significantly decreased in all groups.Conclusion: It was found that as the number of pack-year increased, CD and HEX values decreased and AVG and CV values increased.Dry eye tests were affected in a shorter period of time, while CCT was affected in a longer period of time than the time required forCD, HEX, AVG and CV parameters to be affected.

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Cite This Article

UĞURLU, A., SUNAR, M., KARAKURT, Y., AGCAYAZI, S. B., İÇEL, E., TASLI, N. G., UÇAK, T. (2022). Evaluation of the effect of chronic smoking habit on corneal endothelial cells, central corneal thickness and dry eye tests. Annals of Medical Research, Cilt: 26 - Sayı: 5, 888–893. https://ajindex.com/articles/446817

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References (18)

  1. World Health Organization, & Research for International Tobacco Control. WHO report on the global tobacco epidemic, 2008: The MPOWER package. World Health Organization
  2. Chiba M, Masironi R. Toxic and trace elements in tobacco and tobacco smoke. Bulletin of the World Health Organization 1992;70:269-75
  3. Solberg Y, Rosner M, Belkin M. The association between cigarette smoking and ocular dis-eases. Survey Ophthalmol 1998;42:535-47
  4. Yanbaeva DG, Dentener MA, Creutzberg EC, et al. Systemic effects of smoking. Chest 2007;131:1557-66
  5. Jensen JA, Goodson WH, Hopf HW, et al. Cigarette smoking decreases tissue oxygen. Arch surg 1991;126:1131-4
  6. Fletcher AE. Free radicals, antioxidants and eye diseases: evidence from epidemiological studies on cataract and agerelated macular degeneration. Ophthalmic Res 2010;44:191-8
  7. Fernandez-Robredo P, Moya D, Rodriguez JA, et al. Vitamins C and E reduce retinal oxida-tive stres and nitric oxide metabolites and prevent ultrastructural alterations in porcine hyper-cholesterolemia. Invest Ophthalmol Vis Sci 2005;46:1140-6
  8. Bartecchi CE, MacKenzie TD, Schrier RW. The human costs of tobacco use. N Engl J Med 1994;330:907-12
  9. Milara J, Cortijo J. Tobacco, inflammation, and respiratory tract cancer. Curr Pharm Des 2012;18:3901-38
  10. Handa S, Woo JH, Wagle AM, et al. Awareness of blindness and other smoking-related dis-eases and its impact on motivation for smoking cessation in eye patients. Eye (Lond) 2011;25:117-6
  11. Edwards R, Thornton J, Ajit R, et al. Cigarette smoking and primary open angle glaucoma: a systematic review. J Glaucoma 2008;17:558-66
  12. Moss SE, Klein R, Klein BE. Prevalence of and risk factors for dry eye syndrome. Arch Oph-thalmol 2000;118:1264-8
  13. The Eye Disease Case-Control Study Group. Risk factor for neovascular age-related macular degeneration. Arch Ophthalmol 1992;110:1701-8
  14. Christen WG, Manson JE, Seddon JM, et al. A prospective study of cigarette smoking and risk of cataract in men. J Am Med Assoc 1992;268:989-93
  15. Prummel MF, Wiersinga WM. Smoking and risk of Graves’ disease. J Am Med Assoc 1993;269:479-82
  16. Thorne JE, Daniel E, Jabs DA, et al. Smoking as a risk factor for cystoid macular edema com-plicating intermediate uveitis. Am J Ophthalmol 2008;145:841-6
  17. Velilla S, Garcia-Medina JJ, Garcia-Layana A, et al. Smoking and agerelated macular degen-eration: review and update. J Ophthalmol 2013;2013:895147
  18. Rummenie VT, Matsumoto Y, Dogru M, et al. Tear