Journals / Retina-Vitreus / 2018 / Cilt: 27 - Sayı: 1

Evaluation of Outer Retinal Tubulation in Exudative Age-Related Macular Degeneration

Eksüdatif Yaşa Bağlı Makula Dejeneresansında Dış Retinal Tübülasyon Varlığının Değerlendirilmesi

Pages
11–16
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Treatment may provide anatomical and functional success in exudative AMD even if ORT is seen..

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the features of outer retinal tubulation (ORT) in spectral domain-optical coherence tomography (SD-OCT) imaging in patients with exudative age-related macular degeneration (AMD).
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Key Findings & Data:Materials and Method: SD-OCT images of 586 eyes of 397 patients with the diagnosis of exudative AMD were reviewed retrospectively.
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Conclusion & Impact:Treatment may provide anatomical and functional success in exudative AMD even if ORT is seen..
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the features of outer retinal tubulation (ORT) in spectral domain-optical coherence tomography (SD-OCT) imaging in patients with exudative age-related macular degeneration (AMD). Materials and Method: SD-OCT images of 586 eyes of 397 patients with the diagnosis of exudative AMD were reviewed retrospectively. Thirty eyes of 19 patients with exudative AMD who had ORT were included in the study. The changes and related treatments that have been detected after ORT diagnosis were evaluated. Results: Of the 19 patients, 13 (68.4%) were female and 6 (31.6%) were male. The mean age of the patients was 71.21±16.07 (48-88). The mean num- ber of ORT detected in 30 eyes was 2.4±2.63 [1-13], and the mean number of ORT at fi nal examination was 4.83±5.12 [0-18], which was statistically signifi cant (p 0.05). Mean anti-VEGF injection was 8,33±9,09 [3-36], there was no statistically signifi cant correlation between injections and presence of ORT (r = 0,076, p = 0,695 p> r). The mean central retinal thickness was 215,37±92,2 μm (95-455 μm) initially and 125,17±66,8 μm (38-320 μm) at fi nal and the decrease was signifi cant (p <0.05). Conclusion: The presence of ORT is a degenerative process and may increase with over time. Treatment may provide anatomical and functional success in exudative AMD even if ORT is seen..

Özet

Amaç: Eksüdatif yaşa bağlı makula dejeneresansı (YBMD) tanılı hastalarda spektral domain-optik koherenstomografi (SD-OKT) görüntülemesin- de dış retinal tübülasyon (DRT) saptananların özelliklerinin değerlendirilmesidir. Gereç ve Yöntem: Eksüdatif YBMD tanısı ile takipli 397 hastanın 586 gözüne ait SD-OKT görüntüleri retrospektif olarak incelendi. Dış retinal tübülasyon saptanan 19 eksüdatif YBMD tanılı hastanın 30 gözü çalışmaya alındı. DRT tanısı konulmasından itibaren saptanan değişiklikler ve uygulanan tedaviler ve ilişkilileri değerlendirildi. Bulgular: 19 hastanın 13 (%68.4)’ü kadın, 6 (%31.6)’sı erkekti. Hastaların yaş ortalaması 71,21±16,07 (48-88) olarak saptandı. 30 gözün ilk tübülas- yon saptandığındaki ortalama DRT sayısı 2,4±2,63 [1-13], son muayenedeki ortalama DRT sayısı 4,83±5,12 [0-18] saptandı ve bu artış istatistiksel olarak anlamlı saptandı (p 0.05). Ortalama intravitreal anti-vasküler endotelyal büyüme faktörü (VEGF) enjeksiyonu 8,33±9,09 [3-36] idi ve yapılan enjeksiyonlar ile dış retinal tubulasyon varlığı arasında istatistiksel açıdan korelasyon ve anlamlı ilişki saptanmadı (r=0,076, p=0,695 p>r). Ortalama santral retinal kalınlık başlangıçta 215,37±92,2 μm (95-455 μm) iken son muayene ortalaması 125,17±66,8 μm(38- 320 μm)olarak bulunmuştur ve azalma anlamlı bulunmuştur (p<0.05). Sonuçlar: Dış retinal tubulasyon varlığı dejeneratif bir süreçtir ve zamanla artış gösterebilmektedir. Eksüdatif YBMD’de DRT görülse bile tedaviye devam edilmesi anatomik ve fonksiyonel başarı sağlayabilmektedir.

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Cite This Article

CEBECİ, Z., UĞURLU, A., KIR, N. (2018). Evaluation of Outer Retinal Tubulation in Exudative Age-Related Macular Degeneration. Retina-Vitreus, Cilt: 27 - Sayı: 1, 11–16. https://ajindex.com/articles/307595

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