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Journals / Annals of Medical Research / 2021 / Cilt: 28 - Sayı: 9

Effects of high dose vitamin C administration in Covid-19 patients

Umut Kara
Ender Sir
Ilker Ozdemirkan
Fatih Simsek
Sami Eksert
Serkan Senkal
Mehmet Emin Ince
Deniz Dogan
Canturk Tascı
Ahmet Cosar
Umit Savasci
Gulden Yilmaz
Ufuk Turan
Hasan Yonca
Irmak Tahmaz
Ertugrul Yazici
Pages
1699–1703
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, a significant difference was observed between the groups in terms of changes in renal function tests, and CRP values (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: There is currently no pharmacotherapy with for the treatment of COVID-19.
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Key Findings & Data:We aimed to investigate the effects of early and high-dose vitamin C (VC) therapy in hospitalized patients with COVID-19.
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Conclusion & Impact:However, a significant difference was observed between the groups in terms of changes in renal function tests, and CRP values (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: There is currently no pharmacotherapy with for the treatment of COVID-19. We aimed to investigate the effects of early and high-dose vitamin C (VC) therapy in hospitalized patients with COVID-19. Materials and Methods: We included patients (n=139) who received high-dose VC supplement to the standard treatment protocol into group 1 (n=58), and only those who received a standard treatment protocol into group 2 (n=81). The patients' requirement for supplemental oxygen therapy, requirement for intensive care treatment and survival rates was investigated retrospectively. Furthermore, the changes in white blood cell, C-reactive protein (CRP), procalcitonin, D-Dimer, renal function tests, ferritin, and interleukin 6 values during hospitalization were evaluated. Results: When the groups were compared in terms of clinical data, there was no significant difference in terms of the patients requiring supplemental oxygen therapy (p=0.808), requiring intensive care (p=0.662), and survival rates (p=0.185). However, a significant difference was observed between the groups in terms of changes in renal function tests, and CRP values (p

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Cite This Article

Kara, U., Sir, E., Ozdemirkan, I., Simsek, F., Eksert, S., Senkal, S., Ince, M. E., Dogan, D., Tascı, C., Cosar, A., Savasci, U., Yilmaz, G., Turan, U., Yonca, H., Tahmaz, I., Yazici, E. (2022). Effects of high dose vitamin C administration in Covid-19 patients. Annals of Medical Research, Cilt: 28 - Sayı: 9, 1699–1703. https://ajindex.com/articles/445832

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