Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2016 / Cilt: 63 - Sayı: 2

Incidental pulmonary trophoblastic embolism in a chinchilla

Bir çinçilada tesadüfen karşılaşılan akciğer trofoblast embolisi

Pages
211–213
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

And also,lymphocytic and histiocytic inflammatory cells infiltration were observed around the alveoli and bronchi-bronchioles.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This case study presents the pathomorphological description of a pulmonary trophoblastic embolism in a femalechinchilla, which died due to respiratory distress.
📊
Key Findings & Data:Histopathological examination demonstrated one or more giant cells with rather large nuclei and a broad cytoplasm in thealveolar capillaries, which appeared as multifocal areas.
💡
Conclusion & Impact:And also,lymphocytic and histiocytic inflammatory cells infiltration were observed around the alveoli and bronchi-bronchioles.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This case study presents the pathomorphological description of a pulmonary trophoblastic embolism in a femalechinchilla, which died due to respiratory distress. Routine necropsy examination revealed the presence of multiple small and greycoloured foci, which presented with a hyperaemic and multifocal appearance on the surface of the lungs. Samples taken from thelung tissue were subjected to routine tissue processing and stained with haematoxylin-eosin (HE) and periodic acid-Schiff (PAS)reagents. Histopathological examination demonstrated one or more giant cells with rather large nuclei and a broad cytoplasm in thealveolar capillaries, which appeared as multifocal areas. These cellular structures were positive for PAS staining. And also,lymphocytic and histiocytic inflammatory cells infiltration were observed around the alveoli and bronchi-bronchioles.

Özet

Bu olguda, dişi bir çinçilanın akciğerlerinde trofoblastik emboli olgusu patomorfolojik olarak tanımlandı. Klinik olarak iştahsızlık ve solunum güçlüğü görüldüğü ve tedaviye yanıt vermeyerek öldüğü bildirildi. Yapılan rutin nekropsi yöntemi sonucu akciğerlerin solgun renkte yer yer hiperemik manzarada olduğu dikkati çekti. Yüzeyinde ise kimi alanlarda çok sayıda küçük ve kırmızı renkte odakların olduğu görüldü. Akciğerlerden alınan doku örnekleri rutin doku takibine alınarak Hematoksilen-eosin (HxE) ve Periodic acid-schiff (PAS) boyamaları yapıldı. Histopatolojik olarak, multifokal alanlar halinde alveoler kapillalarda tek veya birkaç büyük çekirdekli ve geniş sitoplazmalı trofoblast hücreleri gözlendi. Bu yapıların PAS boyamasında pozitif oldukları dikkati çekti. Ayrıca, alveoller ve bronş-bronşiollerin çevresinde lenfosit ve histiyositlerden oluşan yangısal hücre infiltrasyonları görüldü.

🔖

Cite This Article

Kutsal, O., YUMUSAK, N., KUTLU, T. (2022). Incidental pulmonary trophoblastic embolism in a chinchilla. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 63 - Sayı: 2, 211–213. https://ajindex.com/articles/444710

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Billington WD, Weir BJ (1967): Deportation of trophoblast in the chinchilla. J Reprod Fert, 13, 593-595
  2. Burek JD, Goldberg B, Hutchins G, Strandberg JD (1979): The pregnant Syrian hamster as a model to study intravascular trophoblasts and associated maternal blood vessel changes. Vet Pathol, 16, 553-566
  3. Hoflehner G, Golob E (1981): Gestational trophoblastic emboli as possible cause of an acute respiratory distress syndrome. Wien Med Wochenschr, 131, 475-477
  4. Ikarashi T, Takeuchi, S, Ohnishi, Y (1988): Trophoblastic embolism in sudden maternal death. Nippon Sanka Fujinka Gakkai Zasshi, 40, 793-795
  5. Ilha MRS, Bezerra Jr. PS, Sanches AWD, Barros CSL (2000): Trophoblastic pulmonary embolism in chinchillas (Chinchilla laniger). Ciênica Rural, 30, 903-904
  6. Ji L, Brkić J, Liu M, Fu G, Peng C, Wang YL (2013): Placental trophoblast cell differentiation: physiological regulation and pathological relevance to preeclampsia. Mol Aspects Med, 34, 981-1023
  7. Knöfler M, J Pollheimer J (2013): Human placental trophoblast invasion and differentiation: a particular focus on Wnt signaling. Front Genet, 4, 1-14
  8. Roffman BY, Simons M (1969): Syncytial trofhoblastic embolism associated with placenta increta and preeclampsia. Am J Obst & Gynec, 104, 1218-1220
  9. Trotter RF, Tieche HL (1956): Maternal death due to pulmonary embolism of trophoblastic cells. Am J Obst & Gynec, 71, 1114-1118
  10. Wagner D (1967): Trophoblastic cells in the blood stream in normal and abnormal pregnancy. Acta Cytol, 12, 137- 139.