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Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2017 / Cilt: 64 - Sayı: 3

Lipid peroxidation level and antioxidant enzyme activities in septicemic calves

Septisemili buzağılarda lipid peroksidasyon düzeyi ve antioksidan enzim aktiviteleri

Öğünç MERAL
Nazlı ERCAN
Ulvi Reha FİDANCI
Pages
161–164
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Septicemic calves had significantly higher levels of GPx, SOD and total bilirubin as compared to the controls (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In recent years, studies showed that there is a close relationship between oxidative stress and pathogenesis of the disease.
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Key Findings & Data:The materials of this study are 40 septicemic and 13 healthy calves.
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Conclusion & Impact:Septicemic calves had significantly higher levels of GPx, SOD and total bilirubin as compared to the controls (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In recent years, studies showed that there is a close relationship between oxidative stress and pathogenesis of the disease. The aim of the study is to determine the serum malondialdehyde (MDA) levels for lipid peroxidation status and serum glutathione peroxidase (GPx), superoxide dismutase (SOD), total bilirubin and albumin levels for antioxidant activities to find out the possible relationship between oxidative stress and septicemia in calves. The materials of this study are 40 septicemic and 13 healthy calves. No significant differences were observed for serum MDA and albumin levels between septicemic and healthy groups (p>0.05). Septicemic calves had significantly higher levels of GPx, SOD and total bilirubin as compared to the controls (p

Özet

Oksidatif stres ile hastalıkların patogenezi arasındaki ilişki son yıllarda gerçekleştirilen değişik çalışmalarla açıklanmaya çalışılmıştır. Bu çalışmada septisemili buzağılarda lipid peroksidasyon ürünü olan serum malondialdehit (MDA) ve antioksidan savunma sisteminin parametreleri olan serum glutatyon peroksidaz (GPx), süperoksit dismutaz (SOD) enzimleri ile total bilirubin ve albumin düzeylerinin belirlenerek neonatal septisemi ile ilişkisinin gösterilmesi amaçlanmıştır. Çalışmanın materyalini 13 sağlıklı ve 40 septisemili buzağı serum örnekleri oluşturmaktadır. Septisemili grup ile kontrol grubu arasında serum MDA ve albümin düzeyleri arasında fark bulunamamıştır (p>0.05). Septisemili buzağıların serum GPx, SOD ve total bilirubin düzeylerindeki artış kontrol grubu ile karşılaştırıldığında istatistiksel olarak anlamlı bulunmuştur (p

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Cite This Article

MERAL, Ö., ERCAN, N., FİDANCI, U. R. (2022). Lipid peroxidation level and antioxidant enzyme activities in septicemic calves. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 64 - Sayı: 3, 161–164. https://ajindex.com/articles/444652

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References (15)

  1. Ayala A, Munoz MF, Argüelles S (2014): Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal. Oxid Med Cell Longev, 2014, 360438. Basoglu A, Sen I, Sevinc M, Simsek A (2004): Serum concentrations of tumor necrosis factor-alpha in neonatal calves with presumed septicemia. J Vet Intern Med, 18, 238- 241. Batra S, Kumar R, Kapoor AK ve ark. (2000): Alterations in antioxidant status during neonatal sepsis. Ann Trop Paediatr, 20, 27-33.
  2. Benzer F, Ozan ST (2003): Fasciola hepatica ile enfekte koyunlarda lipid peroksidasyonu, antioksidant enzimler ve nitrik oksit düzeyleri. Turk J Vet Anim Sci, 27, 657-661.
  3. Celi P (2011): Biomarkers of oxidative stress in ruminant medicine. Immunopharmacol Immunotoxicol, 33, 233-240.
  4. Czerska M, Mikolajewska K, Zielinski M ve ark. (2015): Today's oxidative stress markers. Med Pr, 66, 393-405.
  5. Davutoglu M, Guler E, Olgar S ve ark. (2008): Oxidative stress and antioxidant status in neonatal hyperbilirubinemia. Saudi Med J, 29, 1743-1748.
  6. Ercan N, Fidancı UR (2012): Piyodermalı köpeklerde idrarda 8-hidroksi-2' deoksiguanozin (8-OHdG) düzeyleri. Ankara Univ Vet Fak Derg, 59, 163-168.
  7. Ercan N, Tuzcu N, Başbug O ve ark. (2014): The evaluation of ımportant biomarkers in healthy cattle. Kafkas Üniv Vet Fak Derg, 20, 749-755.
  8. Fecteau G, Van Metre DC, Pare J ve ark. (1997): Bacteriological culture of blood from critically ill neonatal calves. Can Vet J, 38, 95-100.
  9. Gazioğlu A, Güvenç M (2015): Leptospirozisli danalarda oksidatif stres ve bazı biyokimyasal parametreler. F Ü Sağ Bil Vet Derg, 29, 45-48.
  10. Ghanbarpour R, Oswald E (2009): Characteristics and virulence genes of Escherichia coli isolated from septicemic calves in southeast of Iran. Trop Anim Health Prod, 41, 1091-1099.
  11. Halliwell B, Chirico S (1993): Lipid peroxidation: Its mechanism, measurement, and significance. Am J Clin Nutr, 57, 715-724.
  12. Hassan N, Sheikh GN, Hussian SA ve ark. (2014): Variation in clinical findings associated with neonatal colibacillosis in lambs before and after treatment. Veterinary World, 7, 262-265.
  13. Heffner JE, Repine JE (1989): Pulmonary strategies of antioxidant defense. Am Rev Respir Dis, 140, 531-554.
  14. Huang WC, Juang SW, Liu IM ve ark. (1999): Changes of superoxide dismutase gene expression and activity in the brain of streptozotocin-induced diabetic rats. Neurosci Lett, 275, 25-28.
  15. Janero DR (1990): Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation a