Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2014 / Cilt: 20 - Sayı: 2

Serum Ceruloplasmin, Paraoxanase and Nitric Oxide Levels in Akkaraman Sheep with High Nitrate in Drinkıng Water

İçme sularında yüksek nitrat bulunan akkaraman koyunlarda serum seruloplazmin, paraoksanaz ve nitrik oksit düzeyleri

Pages
239–242
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These results suggest that adverse effects of nitrates on Akkaraman sheep occur at concentrations present in the fields.

📌 3 Key Takeaways

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Objective & Hypothesis:The data obtained by Ankara Refik Saydam Hıfzısıhha center, in the scope of the routine monitoring works carried out at Nevşehir/ Hacıbektaş regions’wells were found high nitrate content.
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Key Findings & Data:Nitrate values of three well water sampling points in the province of Yalnızağıl obtained from the monitoring works 69.7 mg/L, 56.8 mg/L and 59.4 mg/L nitrate ratios were found.
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Conclusion & Impact:These results suggest that adverse effects of nitrates on Akkaraman sheep occur at concentrations present in the fields.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The data obtained by Ankara Refik Saydam Hıfzısıhha center, in the scope of the routine monitoring works carried out at Nevşehir/ Hacıbektaş regions’wells were found high nitrate content. Nitrate values of three well water sampling points in the province of Yalnızağıl obtained from the monitoring works 69.7 mg/L, 56.8 mg/L and 59.4 mg/L nitrate ratios were found. The purpose of this study isinvestigate the changes of serum ceruloplasmin, paraoxonase and nitric oxide levels in Akkaraman sheep with high nitrate in drinking water. In this study, Akkaraman sheep which is the animal population of region were used as material. The blood samples collected from Akkaraman sheep were analyzed in terms of ceruloplasmin, paraoxonase and nitric oxide levels by spectrophotometry. Serum ceruloplasmin, paraoxonase and nitric oxide levels was found, 10.68±0.14 uM; 10.80±0.32 uM: 151.36±14.95 U/ml, 142.57±17.85 U/ml and 2.01±0.30 U/ml, 0.99±0.11 U/ml by means of control and study groups respectively. Statistically, Serum ceruloplasmin levels were significantly lower in the study group compared with control group. In addition, although paraoxanase and nitric oxide levels in serum were not show significant differences between groups, measurments reveal that paraoxanase levels were lower in study groups. These results suggest that adverse effects of nitrates on Akkaraman sheep occur at concentrations present in the fields.

Özet

Nevşehir/Hacıbektaş ilçesinde kuyulardan alınan su örneklerinde, Ankara Refik Saydam Hıfzısıhha Merkezinde analizi neticesinde, sularda normalin üstünde nitrat olduğu anlaşılmıştır. İzleme çalışmaları kapsamında Yalnızağıl mevkiindeki 3 kuyudan alınannumunelerinde 69.7 mg/L, 56.8 mg/L ve 59.4 mg/L oranlarında nitrata rastlanmıştır. Bu çalışmanın amacı, içme sularında yüksek düzeyde nitrat bulunan Akkaraman koyunlarında serum seruloplazmin, paraoksanaz ve nitrik oksit düzeylerindeki değişimleri araştırmaktır. Çalışmada bölgedeki Akkaraman koyunları materyal olarak kullanılmıştır. İçme sularında yüksek oranda nitrat bulunan koyunlardan kan örnekleri alınarak serum seruloplazmin, paraoksanaz ve nitrik oksit düzeyleri analiz edilmiştir. Serum seruloplazmin, paraoksanaz ve nitrik oksit düzeyleri spektrofotometrik olarak ölçülmüştür. Serum seruloplazmin, paraoksanaz ve nitrik oksit düzeyleri kontrolçalışma gruplarında sırasıyla 10.68±0.14 uM; 10.80±0.32 uM: 151.36±14.95 U/ml; 142.57±17.85 U/ml ve 2.01±0.30 U/ml; 0.99±0.11 U/ml bulunmuştur. Serum seruloplazmin düzeyleri çalışma grubunda kontrol grubuna göre istatiksel olarak önemli düzeyde düşük bulunmuştur. Serum paraoksanaz ve nitrik oksit düzeyleri gruplar arasında istatiksel önemli farklılık göstermemekle birlikte serum paraoksanaz düzeyleri çalışma grubunda daha düşük düzeylerde ölçülmüştür. Bu sonuçlar doğrultusunda, Akkaraman koyunlarda nitratın olumsuz etkilerinin mevcut konsantrasyonlarda meydana geldiği düşünülmektedir.

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Cite This Article

NASIRI, F., GÜNEŞ, V., MERAL, Ö., PEKCAN, M., KISMALI, G., SALMANOĞLU, B., SEL, T. (2014). Serum Ceruloplasmin, Paraoxanase and Nitric Oxide Levels in Akkaraman Sheep with High Nitrate in Drinkıng Water. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 20 - Sayı: 2, 239–242. https://ajindex.com/articles/272656

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