Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2022 / Cilt: 69 - Sayı: 1

Pulmonary Veno-Occlusive Disease in a Cat with Lymphoma

Lenfomalı Bir Kedide Pulmoner Veno-Oklüzif Hastalık

Pages
105–109
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case report, pathomorphological evaluation of PVOD was performed and as a result of clinicopathological examinations; PVOD, intestinal lymphoma, and cardiac metastasis were described in a male cat.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pulmonary veno-occlusive disease (PVOD) is an uncommon disease in humans and animals caused by pulmonary hypertension (PH).
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Key Findings & Data:A mass was detected in the right atrium with echocardiography in an 11-year-old male cat.
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Conclusion & Impact:In this case report, pathomorphological evaluation of PVOD was performed and as a result of clinicopathological examinations; PVOD, intestinal lymphoma, and cardiac metastasis were described in a male cat.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Pulmonary veno-occlusive disease (PVOD) is an uncommon disease in humans and animals caused by pulmonary hypertension (PH). The aim of this study was to investigate pathomorphological findings of PVOD in a cat. A mass was detected in the right atrium with echocardiography in an 11-year-old male cat. Following treatments, necropsy of the cat was performed after death due to respiratory failure. Macroscopically, masses were detected in mesenteric lymph node, mediastinal lymph node and, heart. Congestion and consolidated areas with edema were seen in the examination of the lung. Histopathologically, neoplastic lymphoid cells were observed in intestine, lymph nodes and heart. In lung, vein lumens were almost completely occluded by mostly loose intimal fibrosis. Near affected veins, increasing in number of the capillaries was observed. While intimal fibrosis was detected by Masson’s trichrome staining, the occluded veins were demonstrated by Verhoeff-van Gieson staining. In this case report, pathomorphological evaluation of PVOD was performed and as a result of clinicopathological examinations; PVOD, intestinal lymphoma, and cardiac metastasis were described in a male cat.

Özet

Pulmoner Veno-Oklüzif Hastalık (PVOH) pulmoner hipertansiyonun (PH) neden olduğu, insanlarda ve hayvanlarda nadir görülen bir hastalıktır. Bu olgu ile bir kedide gözlenen Pulmoner Veno-Oklüzif Hastalık’ın patomorfolojik yönden incelenmesi amaçlanmıştır. 11 yaşlı erkek kedinin ekokardiyografisinde sağ atriumda kitle gözlendi. Tedavilerin ardından solunum güçlüğüne bağlı ölen kedinin nekropsisi yapıldı. Makroskobik olarak, mezenteriyal ve mediastinal lenf yumrularında ve kalpte kitleler ile karşılaşıldı. Akciğer muayenesinde ödem ve konjesyon ile konsolide alanlar görüldü. Histopatolojik olarak bağırsak, lenf yumruları ve kalpte neoplastik lenfoid hücreler gözlendi. Akciğerde şiddetli intimal fibrozise bağlı venlerin lümenlerinde daralma ve tıkanmalar dikkati çekti. Etkilenen çoğu damarların çevresinde kapillarizasyon gözlendi. Masson trikrom boyamasıyla intimal fibrozis tespit edilirken, tıkalı damarlar Verhoeff-van Gieson boyamasıyla gösterildi. Bu olguda bir kedide PVOH patomorfolojik yönden değerlendirilmiş ve klinikopatolojik incelemeler sonucunda erkek bir kedide PVOH, intestinal lenfoma ve kardiyak metastazı tanımlanmıştır.

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Cite This Article

TENEKECİ, G. Y., TERZİ, O. S., ŞAHAL, M., HAZIROĞLU, R. (2022). Pulmonary Veno-Occlusive Disease in a Cat with Lymphoma. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 69 - Sayı: 1, 105–109. https://ajindex.com/articles/444391

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