SavedAdd your journal

Journals / Ankara Üniversitesi Tıp Fakültesi Mecmuası / 2005 / Cilt: 58 - Sayı: 2

Transport proteins in bile production

Safra oluşumunda rol oynayan transport proteinleri

Bilge CEYDİLEK
Ali Reşit BEYLER
Pages
68–72
Publication Date
2022-10-10
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, it was aimed to determine the transport proteins in bile production and present the recent literature about them.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:New opinions in the production of bile have been reporting today.
📊
Key Findings & Data:In the light of these opinions, the mechanism of development of bile ducts diseases has gradually become clear.
💡
Conclusion & Impact:In this review, it was aimed to determine the transport proteins in bile production and present the recent literature about them.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

New opinions in the production of bile have been reporting today. In the light of these opinions, the mechanism of development of bile ducts diseases has gradually become clear. In this review, it was aimed to determine the transport proteins in bile production and present the recent literature about them.

Özet

Son yıllarda safra oluşumuyla ilgili yeni görüşler ortaya çıkmış ve yeni bilgiler ışığında hastalıkların oluşum mekanizmaları aydınlanmaya başlamıştır. Bu derlemede, safra oluşumunda rol oynayan taşıyıcı proteinleri tanımlamak ve bugüne kadar bu konuda elde edilmiş olan bilgi birikimini sunmak amaçlanmıştır.

🔖

Cite This Article

CEYDİLEK, B., BEYLER, A. R. (2022). Transport proteins in bile production. Ankara Üniversitesi Tıp Fakültesi Mecmuası, Cilt: 58 - Sayı: 2, 68–72. https://ajindex.com/articles/444053

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Saunders WB. editor. Guyton & Hall Tıbbi Fizyoloji. İstanbul: Nobel Tıp Kitabevi, 1996; p.886
  2. Champe PC, Harvey RA. editors. Lippincott’s Biyokimya. İstanbul:Nobel Tıp Kitabevi, 1997; p. 210-213
  3. Reichen J. Theroleofthesinusoidalendotheliuminliverfunction.News Physiol. Sci. 1999; 14:117-21
  4. Feldman M, Schorschmidt BF, Sleiseger MH. editors. Gastrointestinal and Liver Disease. Pheladelphia/London:Saunders, 1998; p.937-48
  5. Meier PJ. Molecular mechanisms of hepatic bile salt transport from sinusoidal blood into bile. Am. J. Physiol. Gastrointest. Liver Physiol. 1995; 269:G801-G12
  6. Groothuis GM, Hardonk MJ, Keulemans KP et al. Autoradiographic and kinetic demonstration of acine heterogeneity of taurocholate transport. Am.J.Physiol. Gastrointest. Liver Physiol. 1982; 243:G455-G62
  7. Hagenbuch B, Steiger B, Foguet M et al. Functional expression cloning and characterization of the hepatocyte Na/bile acid co-transport system. Proc. Natl. Acad. Sci. USA.1991; 88:10629-33
  8. Cattori V, Eckhardt U, Hagenbuch B. Molecular cloning and fonctional characterization of two alternatively sliced Ntcp isoforms from Mouse liver. Biocim. Biophys. Acta. 1999; 1445:154-59
  9. Kramer W, Stengelin S, Baringhaus KH et al. Substrate specificityof the ileal and the hepatic Na/bile acid cotransporters of the rabbit 1. transport studies with membrane vesicles and cell lines expressing the cloned transporters. J. Lipid Res. 1999; 40:1604-17
  10. Hagenbuch B, Meier PJ. Molecular cloning chromosomal localization and function characterization of human liver Na/bile acid cotransporter. J. Clin. Invest. 1994; 93:1326-31
  11. Meier PJ, Eckhardt U, Schroder A, et al. Substrate specificityofsinusoidal bile acid and organic anion uptake systems in rat and human liver. Hepatology. 1997; 26:1667-77
  12. Hardikar W, Anonthanarayenan M, Suchy FJ. Differantialoncogenic regulation of basolateral and canalicular bile acid transport proteins in rat liver. J. Biol. Chem. 1995; 270:20841-46
  13. Suchy FJ, Bucuvalas JC, Goodrich AL et al. Taurocholate transport and Na-K-ATP ase activity in fetal and liver plasma membrane vesicles. Am. J. Physiol. Gastrointest. Liver Physiol. 1986; 251:G665-73
  14. Gren RM, Gollon JL, Hagenbuch B, et al. Regulation of hepatocyte bile salt transporters diving hepatic regeneration. Am.J.Physiol.Gastrointest. Liver Physiol. 1997; 273:G621-G27
  15. Hagenbuch B. Scharschmidt BF, Meier PJ. Effectofantisenseoligonucleotides on the expression of hepatocellular b