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Journals / Ankara Üniversitesi Tıp Fakültesi Mecmuası / 2022 / Cilt: 75 - Sayı: 2

Living Donor Liver Transplantation Early Period Outcomes with the High MELD-Na Scores: Single Center Experience

Yüksek MELD-Na Skoru ile Canlı Donörden Karaciğer Transplantasyonu Planlanan Hastalarda Erken Dönem Sonuçlarımız: Tek Merkez Deneyimi

Süheyla Karadağ Erkoç
Elif Beyza Başkan
Yonca Altunbaş
Elvan Onur Kırımker
Deniz Balcı
Mustafa Kemal Bayar
Ali Abbas Yılmaz
Pages
259–267
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to the preoperative MELD-Na score calculated after the treatments applied during the preparation period, the patients were divided into two groups as

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Living donor liver transplantation (LDLT) can be performed more frequently due to insufficient cadaver organ donation.
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Key Findings & Data:Materials and Methods: In our study, adult patients with a MELD-Na score of ≥25 between January 2015 and December 2021 were evaluated retrospectively.
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Conclusion & Impact:According to the preoperative MELD-Na score calculated after the treatments applied during the preparation period, the patients were divided into two groups as
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: Living donor liver transplantation (LDLT) can be performed more frequently due to insufficient cadaver organ donation. In cases where the number of cadaveric organ is not sufficient patients with high MELD-Na score stand out during waiting. In this study, the effect of high MELD- Na score on early postoperative outcome was investigated in LDLT. Materials and Methods: In our study, adult patients with a MELD-Na score of ≥25 between January 2015 and December 2021 were evaluated retrospectively. According to the preoperative MELD-Na score calculated after the treatments applied during the preparation period, the patients were divided into two groups as

Özet

Amaç: Canlı donör karaciğer transplantasyonu (CDKT), yeterli sayıda kadavra organ donörü olmaması nedeni ile daha sık yapılabilmektedir. Kadavra organ sayısının yeterli olmadığı durumlarda bekleme listesinde MELD-Na skoru yüksek olan hastalar öne çıkmaktadır. Bu çalışmada CDKT’de, yüksek MELD-Na skorunun erken postoperatif sonuçlar üzerine etkisi araştırıldı. Gereç ve Yöntem: Çalışmamızda Ocak 2015-Aralık 2021 tarihleri arasında MELD-Na skoru ≥25 olan erişkin hastalar retrospektif olarak değerlendirildi. Hazırlık döneminde uygulanan tedavilerden sonra hesaplanan preoperatif MELD-Na skoruna göre hastalar

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Cite This Article

Erkoç, S. K., Başkan, E. B., Altunbaş, Y., Kırımker, E. O., Balcı, D., Bayar, M. K., Yılmaz, A. A. (2022). Living Donor Liver Transplantation Early Period Outcomes with the High MELD-Na Scores: Single Center Experience. Ankara Üniversitesi Tıp Fakültesi Mecmuası, Cilt: 75 - Sayı: 2, 259–267. https://ajindex.com/articles/443401

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References (14)

  1. Kim WR, Biggins SW, Kremers WK, et al. Hyponatremia and mortality among patients on the liver-transplant waiting list. N Engl J Med. 2008;359:1018- 1026
  2. Leise MD, Kim WR, Kremers WK, et al. A revised model for end-stage liver disease optimizes prediction of mortality among patients awaiting liver transplantation. Gastroenterology. 2011;140:1952-1960
  3. Ruf AE, Kremers WK, Chavez LL, et al. Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone. Liver Transpl. 2005;11:336-343
  4. Feng S. Living donor liver transplantation in high Model for End-Stage Liver Disease score patients. Liver Transpl. 2017;23:9-21
  5. Selzner M, Kashfi A, Cattral MS, et al. Live donor liver transplantation in high MELD score recipients. Ann Surg. 2010;251:153-157
  6. Chok KSh, Chan SC, Fung JY, et al. Survival outcomes of right-lobe living donor liver transplantation for patients with high Model for End-stage Liver Disease scores. Hepatobiliary Pancreat Dis Int. 2013;12:256-262
  7. Klein KB, Stafinski TD, Menon D. Predicting survival after liver transplantation based on pre-transplant MELD score: a systematic review of the literature. PLoS One. 2013;8:e80661
  8. Berg CL, Merion RM, Shearon TH, et al. Liver transplant recipient survival benefit with living donation in the model for endstage liver disease allocation era. Hepatology. 2011;54:1313-1321
  9. Ivanics T, Leonard-Murali S, Mouzaihem H, et al. Extreme hyponatremia as a risk factor for early mortality after liver transplantation in the MELD- sodium era. Transpl Int. 2021;34:2856-2868
  10. Wiesner R, Edwards E, Freeman R, et al. Model for end-stage liver disease (MELD) and allocation of donor livers. Gastroenterology. 2003;124:91-96
  11. Sharma P, Schaubel DE, Gong Q, et al. End-stage liver disease candidates at the highest model for end-stage liver disease scores have higher wait-list mortality than status-1A candidates. Hepatology. 2012;55:192-198
  12. Samuel D, Coilly A. Management of patients with liver diseases on the waiting list for transplantation: a major impact to the success of liver transplantation. BMC Med. 2018;16:113
  13. Moon DB, Lee SG, Kang WH, et al. Adult Living Donor Liver Transplantation for Acute-on-Chronic Liver Failure in High-Model for End-Stage Liver Disease Score Patients. Am J Transplant. 2017;17:1833-1842
  14. Cholankeril G, Li AA, Dennis BB, et al. Pre-Operative Delta-MELD is an Independent Predictor of Higher Mortality following Liver Transpla