Journals / Anatolian Journal of Emergency Medicine / 2020 / Cilt: 3 - Sayı: 4

Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department

Akut Koroner Sendromda Değiştirilebilir Risk Faktörleri ile Kan Hücresi Tipleri Arasındaki İlişki ve Acil Serviste Mortalite Tahmini

Pages
111–116
Publication Date
2022-10-12
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Female gender was found to be higher in theNSTEMI group than in the STEMI group and also the hypertensionratio was found to be higher in the NSTEMI group than in the STEMIgroup and it was found to be statistically significant.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Inflammatory mediators such as leukocyte count (WBC),neutrophil / lymphocyte ratio (NLR), platelet / lymphocyteratio(PLR), platelet distribution width (PDW) and C reactive protein(CRP) are used for the prediction of ischemic vascular events suchas acute coronary syndrome (ACS).In this study, the relationshipbetween inflammatory mediators and modifiable risk factors in thediagnosis of ACS and mortality was examined.Material and methods: A total of 100 patients with ST elevationmyocardial infarction (STEMI) and non-ST elevation myocardialinfarction (NSTEMI) were included in the study.
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Key Findings & Data:Blood samples forWBC, neutrophil count, NLR, PLR, PDW and CRP and routine bloodlaboratory studies were taken at the time of admission of thepatients.Results: Of the patients diagnosed with ACS,49% was STEMIand 51% was NSTEMI.
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Conclusion & Impact:Female gender was found to be higher in theNSTEMI group than in the STEMI group and also the hypertensionratio was found to be higher in the NSTEMI group than in the STEMIgroup and it was found to be statistically significant.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Inflammatory mediators such as leukocyte count (WBC),neutrophil / lymphocyte ratio (NLR), platelet / lymphocyteratio(PLR), platelet distribution width (PDW) and C reactive protein(CRP) are used for the prediction of ischemic vascular events suchas acute coronary syndrome (ACS).In this study, the relationshipbetween inflammatory mediators and modifiable risk factors in thediagnosis of ACS and mortality was examined.Material and methods: A total of 100 patients with ST elevationmyocardial infarction (STEMI) and non-ST elevation myocardialinfarction (NSTEMI) were included in the study. Blood samples forWBC, neutrophil count, NLR, PLR, PDW and CRP and routine bloodlaboratory studies were taken at the time of admission of thepatients.Results: Of the patients diagnosed with ACS,49% was STEMIand 51% was NSTEMI. Female gender was found to be higher in theNSTEMI group than in the STEMI group and also the hypertensionratio was found to be higher in the NSTEMI group than in the STEMIgroup and it was found to be statistically significant. The NLRmedian value between the STEMI and NSTEMI diagnostic groupswas found to be higher in the NSTEMI group and statistically moresignificant.Conclusions: In conclusion; troponin, control troponin,lymphocyte and NLR ratio were found to be statistically significantbetween STEMI and NSTEMI diagnostic groups.In addition to this;age was found as an effective parameter on mortality.

Özet

Amaç: Lökosit sayısı (WBC), nötrofil / lenfosit oranı (NLR), trombosit / lenfosit oranı (PLR), trombosit dağılım genişliği (PDW) ve C reaktif protein (CRP) gibi inflamatuar medyatörler; akut koroner sendrom (AKS) gibi iskemik olayların tahmininde kullanılmaktadır. Çalışmamızda , AKS tanısında inflamatuar mediatörler , çeşitli risk faktörleri ve mortalite arasındaki ilişki incelenmiştir. Gereç ve Yöntem: Çalışmaya ST elevasyonlu miyokard enfarktüsü (STEMI) ve ST elevasyonu olmayan miyokard enfarktüsü (NSTEMI) tanısı olan toplam 100 hasta dahil edildi. Hastaların acile başvuru anındaki sırasında WBC, nötrofil sayımı, NLR, PLR, PDW,CRP değerleri ve diğer biokimyasal belirteçler için kan örnekleri alındı. Bulgular: AKS tanısı konan hastaların% 49'u STEMI ve% 51'i NSTEMI idi. Kadın cinsiyetin NSTEMI grubunda STEMI grubuna göre daha yüksek olduğu ve hipertansiyon oranının NSTEMI grubunda STEMI grubuna göre daha yüksek olduğu ve istatistiksel olarak anlamlı olduğu saptandı. STEMI ve NSTEMI tanı grupları arasındaki NLR medyan değeri, NSTEMI grubunda daha yüksek ve istatistiksel olarak daha anlamlı bulundu. Sonuç: Sonuç olarak; STEMI ve NSTEMI tanı grupları arasında troponin, kontrol troponin, lenfosit ve NLR oranının anlamlı farklılık gösterdiği bulunurken yaşın mortalite üzerinde etkili bir parametre olduğu görülmektedir.

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Cite This Article

DURAK, V. A., LEYLEK, H. E., KÖKSAL, Ö. (2022). Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. Anatolian Journal of Emergency Medicine, Cilt: 3 - Sayı: 4, 111–116. https://ajindex.com/articles/439373

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