Journals / Anatolian Journal of Emergency Medicine / 2020 / Cilt: 3 - Sayı: 1

A Rare Symptom And An Important Disease:Hyperpigmentation And Primary Adrenal Insufficiency

Nadir Bir Semptom ve Önemli Bir Hastalık : Hiperpigmentasyon ve Primer Adrenal Yetmezlik

Pages
18–20
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The laboratory findings of the patient were: Adrenocorticotropic hormone (ACTH)>1250 pg/mL (reference value:

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim Clinical symptoms of adrenal insufficiency are nonspecific and thus misdiagnosis is common.
📊
Key Findings & Data:This case report is presented to emphasize the importance of the presence of hyperpigmentation in the definition of primary adrenal insufficiency.CaseA 66-year-old male with no previous history of disease presented to our emergency department with complaints of weakness, nausea, and vomiting.
💡
Conclusion & Impact:The laboratory findings of the patient were: Adrenocorticotropic hormone (ACTH)>1250 pg/mL (reference value:
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim Clinical symptoms of adrenal insufficiency are nonspecific and thus misdiagnosis is common. Hyperpigmentation is a specific finding for the diagnosis of primary adrenal insufficiency. This case report is presented to emphasize the importance of the presence of hyperpigmentation in the definition of primary adrenal insufficiency.CaseA 66-year-old male with no previous history of disease presented to our emergency department with complaints of weakness, nausea, and vomiting. On his initial evaluation, blood pressure was 71/55 mmHg. Physical examination revealed darkening of skin color and increased pigmentation on hands and tongue. There were no other significant findings on physical examination. The laboratory findings of the patient were: Adrenocorticotropic hormone (ACTH)>1250 pg/mL (reference value:

Özet

Amaç Adrenal yetmezliğin klinik semptomları spesifik değildir ve bu nedenle yanlış tanı yaygındır. Hiperpigmentasyon, primer adrenal yetmezlik tanısı için spesifik bir bulgudur. Bu olgu primer adrenal yetmezlik tanısında hiperpigmentasyon varlığının önemini vurgulamak amacıyla sunuldu.OlguBilinen hastalık öyküsü olmayan 66 yaşında erkek hasta acil servisimize halsizlik, bulantı ve kusma şikayetleri ile başvurdu. İlk değerlendirmesinde kan basıncı 71/55 mmHg olarak belirlendi. Fizik muayenede cilt renginde koyulaşma, el ve dilde hiperpigmentasyon görüldü. Fizik muayenede başka anlamlı bulgu saptanmadı. Hastanın laboratuvar bulgularında Adrenokortikotropik hormon (ACTH)> 1250 pg / mL (referans değeri:

🔖

Cite This Article

Altuncı, Y. A., Yalçınlı, S., Efe, M. (2022). A Rare Symptom And An Important Disease:Hyperpigmentation And Primary Adrenal Insufficiency. Anatolian Journal of Emergency Medicine, Cilt: 3 - Sayı: 1, 18–20. https://ajindex.com/articles/439345

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (8)

  1. Bornstein SR. Predisposing factors for adrenal insufficiency. N Engl J Med. 2009; 360:2328-2339
  2. Marx JA, Hockberger RS, Walls RM. Rosen's Emergency Medicine. 8th Ed. Elsevier Saunders: 2014
  3. Yanase T, Tajima T, Katabami T, Iwasaki Y, Tanahashi Y, Sugawara A, et al. Diagnosis and treatment of adrenal insufficiency including adrenal crisis: a Japan Endocrine Society clinical practice guideline. Endocr J. 2016;63(9):765-784
  4. Nieman LK, Turner MLC. Addison’s disease. Clinics in Dermatology. 2006;24(4):276-80
  5. Simpson SL. Addison’s disease. BMJ. 1950;4689:1164-6
  6. Charmandari E, Nicolaides NC, Chrousos GP. Adrenal insufficiency. Lancet. 2014;383(9935):2152-67
  7. Hahner S, Loeffler M, Bleicken B, Drechsler C, Milovanovic D, Fassnacht M, et al. Epidemiology of adrenal crisis in chronic adrenal insufficiency: the need for new prevention strategies. Eur J Endocrinol. 2010;162: 597-602
  8. Adams JG, Emergency Medicine, 2nd Ed. Elsevier Saunders 2012.