Journals / Anadolu Tıp Dergisi / 2001 / Cilt: 3 - Sayı: 1

Evaluation of distribution of allergens in adults and children in Gaziantep region with in-vitro screening tests

Gaziantep bölgesinde yetişkin ve çocuklarda görülen allerjenlerin dağılımının in-vitro tarama testleri ile saptanması

Pages
15–21
Publication Date
2022-10-10
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is concluded that, the distribution of allergens in both groups have been differing with many factors such as age, sex, the amount and nature of allergens in different environments.

📌 3 Key Takeaways

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Objective & Hypothesis:In recent years, an increase in the prevalence of allergic diseases has been reported, particularly in industrialised countries.
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Key Findings & Data:In this study, inhalant screening allergens (AlaTOP®), food screening allergens (FP5E®), total and specific IgE levels were measured in 237 allergic patients (164 adults and 73 children), to examine the distribution of allergens, percentage of atopy/non-atopy among allergic children and adults in a developing country which has distinct environments and societies from Western countries.
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Conclusion & Impact:It is concluded that, the distribution of allergens in both groups have been differing with many factors such as age, sex, the amount and nature of allergens in different environments.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In recent years, an increase in the prevalence of allergic diseases has been reported, particularly in industrialised countries. It is also a problem in non-industrialised countries, but its extent has been less well documented. In this study, inhalant screening allergens (AlaTOP®), food screening allergens (FP5E®), total and specific IgE levels were measured in 237 allergic patients (164 adults and 73 children), to examine the distribution of allergens, percentage of atopy/non-atopy among allergic children and adults in a developing country which has distinct environments and societies from Western countries. The percentages of atopy in children and in adults were 45% and 47%, respectively. The percentage of atopic males in the group of children (31%) was higher than for females (13%) while atopic females (25%) were more than males (21%) in adults. Most frequent allergen in childhood was cow milk while it was Lolium perenne(grass) in adults. Total IgE levels were found statistically different between atopic and non-atopic subjects in adults (p0.05). It is concluded that, the distribution of allergens in both groups have been differing with many factors such as age, sex, the amount and nature of allergens in different environments.

Özet

Son yıllarda, özellikle endüstrileşmiş ülkelerde allerjik hastalıkların prevalansında bir artış olduğu saptanmıştır. Bu gelişmekte olan ülkelerinde sorunu olmasına rağmen, konunun içeriği tam olarak aydınlatılmamıştır. Bu çalışmada, Batı toplumlarından farklı çevre ve toplumsal alışkanlıkları olan bölgemizde, 237 allerjik hastada (164 yetişkin ve 73 çocuk) atopi/non-atopi yüzdesi ve allerjenlerin dağılımını saptamak için, inhalar tarama allerjenleri (ALATOP®), besin tarama allerjenleri (FP5E®), total ve spesifik IgE seviyeleri ölçülmüştür. Çocuk ve yetişkinlerde atopi yüzdesi sırasıyla, %45 ve %47 olarak bulunmuştur. Erkek çocuklarda atopi yüzdesi (%31) kız çocuklarından (%13) daha yüksek saptanmıştır. Halbuki, yetişkinlerde atopik kadınların yüzdesinin (%25), erkeklerden (%21) daha fazla olduğu bulunmuştur. Çocuklukta en sık görülen allerjen 'inek sütü' iken yetişkinlerde Lolium perenne olarak tespit edilmiştir. Ayrıca, yetişkinlerdeki atopik ve non-atopik bireylerin total IgE seviyeleri arasında istatistiksel olarak anlamlı fark bulunurken (p0.05). Sonuç olarak, her iki gruptaki allerjenlerin dağılımı, farklı çevrelerdeki allerjenlerin yapısı, miktarı, yaş, cins gibi bazı faktörler ile etkileştiği sonucunu desteklemektedir.

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Cite This Article

ÖZASLAN, J., BAYRAKTAROĞLU, Z., PENÇE, S., YILMAZ, N. (2022). Evaluation of distribution of allergens in adults and children in Gaziantep region with in-vitro screening tests. Anadolu Tıp Dergisi, Cilt: 3 - Sayı: 1, 15–21. https://ajindex.com/articles/438176

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