Journals / Anadolu Tıp Dergisi / 2003 / Cilt: 5 - Sayı: 3

Frequency of thyroid disfunction in primary fibromyalgia syndrome

Primer fibromiyalji sendromlu hastalarda tiroid disfonksiyonu sıklığı

Pages
167–170
Publication Date
2022-10-10
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, we examined various thyroid dysfunction in primary fibromyalgia patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Primary fibromyalgia syndrome is a connective tissue rheumatism that characterized by widespread pain, sleep disturbances, fatigue, and paresthesias.
📊
Key Findings & Data:Demographic characteristics of 109 female that diagnosed as FS according to ACR criteria were analyzed.
💡
Conclusion & Impact:In this study, we examined various thyroid dysfunction in primary fibromyalgia patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Primary fibromyalgia syndrome is a connective tissue rheumatism that characterized by widespread pain, sleep disturbances, fatigue, and paresthesias. The musculo-skeletal symptoms of hypothyroidism are generalized muscle pain, aches in joints, paresthesias. Demographic characteristics of 109 female that diagnosed as FS according to ACR criteria were analyzed. Number of tender points and duration of symptoms were noted. Patients with the history of endocrinologic disorders or treated with steroids in the last 3 months and patients that in the lactation period were excluded from the study. Sleep disturbances, fatigue, stiffness, and pain of patients were evaluated by 0-100 mm VAS and FIQ. Thyroid function tests including freeT3, free T4, and TSH were analyzed at the same time. The mean age was 36.1 ± 8.98 years. The duration of symptoms and the number of tender points were 29 ± 23 months and 14 ± 2. In 9 of 109 patients elevated TSH levels and decreased free T4 levels were found and accepted as hypothyroidism. Symptoms of FS, in which neuro-endocrinologic factors thougth to be responsible for etiology, are similar with the symptoms and signs of hypothyroidism. In this study, we examined various thyroid dysfunction in primary fibromyalgia patients.

Özet

Fibromiyalji sendromu (FS), yaygın ağrı, uyku bozukluğu, kronik yorgunluk, paresteziler ile karakterize yumuşak doku romatizmasıdır. Hipotiroidizmde saptanan kas-iskelet sistemi bulguları ise jeneralize kas ve eklem ağrıları, tutukluk, parestezilerdir. ACR kriterlerine göre FS tanısı alan 109 bayan hastanın demografik özellikleri belirlendi. Hassas nokta sayıları ve hastalık süreleri kaydedildi. Öyküde endokrin hastalığı olanlar, son üç ay içinde steroid grubu ilaç kullanmış olanlar, laktasyon döneminde olanlar araştırma dışı bırakıldı. Hastaların ağrı, uyku bozukluğu, yorgunluk ve tutukluk şikayetleri sorgulamaları 0-100 mm VAS ve FIQ ile değerlendirildi. sT3, sT4, TSH değerleri aynı saatte ve RIA yöntemi ile belirlendi. Araştırmamıza dahil edilen 109 bayan hastanın yaş ortalaması 36.1± 8.98 yıl, hastalık süresi ortalaması 29 ± 23 ay, hassas nokta sayısı 14±2 olarak belirlendi. 109 bayan hastanın 9'unda (%8.2) TSH düzeyi artmış, sT4 düzeyi azalmış olarak saptandı ve klinik hipotiroidizm olarak kabul edildi. Etiyoloj isinde bazı nöroendokrinolojik bozuklukların sorumlu olduğu düşünülen FS'nun semptomları primer hipotiroidizm tablosuyla benzerlik gösterir. Her iki klinik tablonun benzer özellikleri nedeniyle bu araştırmada fibrorniyalji tanılı hastalara eşlik edebilen tiroid disfoksiyonunu saptamayı amaçladık.

🔖

Cite This Article

ALANOĞLU, E., ÇAKCI, A., UŞAN, H., TUNCAY, R., GÜRÇAY, E. (2022). Frequency of thyroid disfunction in primary fibromyalgia syndrome. Anadolu Tıp Dergisi, Cilt: 5 - Sayı: 3, 167–170. https://ajindex.com/articles/438123

References (1)

  1. Bengstton A, Henrikson KG, Jarfeldt L: Primary fıbromyalgia: A clinical and laboratory study of 55 patients. Scand J Rheumatol 1986;15:340-347. 2-Bennet RM, Clark SR, Campbell SM et al: Low levels of somatomedin-C in fıbromyalgia syndrome: A possible link between sleep and muscle pain. Arthritis Rheum 1992;35:113-116. 3-Bennet RM, Clark SR, Campbell SM: Symptoms of raynaud's syndrome in patients with fıbromyalgia. Arthritis Rheum 1991;34:264-269. 4-Ferracioli G, Cavalieri F, Salaffi F, et al: Neuroendocrinologic findings in primary fıbromyalgia and in other chronic rheumatic conditions. J Rheumatol 1990; 17: 869-873. 5-Golding DN:A synopsis of rheumatic diseases. 5th. Ed. London Wright. Publ 1989; 174-175 6- Golding DN: Hypothyroidism presenting with musculoskeletal symptoms. Ann Rheum Dis 1970;29:(10):10-14. 7-Gündoğdu S. Hormon Hastalıkları. Cecil Essentials Of Medicine (Türkçesi) I.baskı. Yalçın A (Ed). İstanbul: Yüce yayınları A.Ş., 1991:673-688. 8- Keenan GF, Ostrov BE, Gold Smith DP et al: Rheumatic symptoms associated with hypotyroidism in children. J Pediatr 1993 Oct; 123:(4):586-588. 9- Neeck G, Riedel W: Thyroid function in patients with fıbromyalgia syndrome. J Rheumatol 1992;19:(7):1120-1122. 10- Wallace DJ: Genitourinary manifestations of fıbrositis: An increased association with female urethral syndrome. J Rheumatol 1990 17:238-239. 11- Wolfe F, Smythe HA, Yunus MB: The American College of Rheumatology 1990 criteria for classification of fibromyalgia: Report of the multicenter criteria commitee. Arthritis Rheum 1990;33:160-172. 12- Yunus MB, Masi AT, Calabro JJ: Primary fibromyalgia (fıbrositis): Clinical study of 50 patients with matched normal controls. Semin Arthritis Rheum 1981; 11:151-171.