Journals / Anadolu Tıp Dergisi / 2003 / Cilt: 5 - Sayı: 3

Migraine attacks and MPV

Migren atakları ve MPV

Pages
159–166
Publication Date
2022-10-10
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As conclusion, our results revealed that platelet count and MPV alterations are not expected findings in migraine cases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The present study has been designed to examine the relationship of total number of platelets and "Mean Platelet Volume" (MPV); an indirect indicator of functional changes of platelets, with migraine attacks.
📊
Key Findings & Data:We evaluated the laboratory findings of the migraine patients during the migraine attack, arid 48 hours and fifteen days after the attack and compared the results with the control group's findings.
💡
Conclusion & Impact:As conclusion, our results revealed that platelet count and MPV alterations are not expected findings in migraine cases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The present study has been designed to examine the relationship of total number of platelets and "Mean Platelet Volume" (MPV); an indirect indicator of functional changes of platelets, with migraine attacks. We evaluated the laboratory findings of the migraine patients during the migraine attack, arid 48 hours and fifteen days after the attack and compared the results with the control group's findings. There weren't any significant differences for platelet count and MPV values neither between the migraine and control groups nor according to gender, age, duration of illness, frequency, duration and lateralization of the attacks in migraine group. As conclusion, our results revealed that platelet count and MPV alterations are not expected findings in migraine cases.

Özet

Bu çalışma, platelet fonksiyon değişikliğinin indirek bir göstergesi olan "Mean Platelet Volume" (MPV) değerlerinin ve platelet sayısının, migrenli hastalarda ataklar ile ilgili değişimini araştırmak amacıyla planlandı. Hastaların, migren atağı esnasında, ataktan 48 saat sonra ve ataktan 15 gün sonraki değerleri incelenerek kontrol grubu ile karşılaştırmalar yapıldı. Çalışmamızın sonuçları, auralı ve aurasız migrenli hastalarda atak anında, ataktan 48 saat sonra ve ataktan 15 gün sonraki platelet sayısı ve MPV değerlerinde istatistiksel olarak anlamlı değişim olmadığını göstermektedir. Ayrıca migrenli hastalarda MPV düzeylerinde cinse ve yaşa bağlı farklılık gözlenmedi. Platelet sayısı ve MPV hasta ve kontrol grubunda farklılık bulunmadı. Hastaların geçirdiği atak sayısı, yıldaki atak sayısı, hastalığın süresi, bir önceki ataktan itibaren süre ve atak süresi, atağın sağa veya sola lateralize olması ile MPV değerlerinde değişme olmadığı saptandı. Sonuçlar migrenli hastalarda platelet sayısında ve MPV değerlerinde ataklara bağlı bir değişimin oluşmadığını göstermektedir.

🔖

Cite This Article

DUMAN, T., ERASLAN, T., MELEK, İ. M. (2022). Migraine attacks and MPV. Anadolu Tıp Dergisi, Cilt: 5 - Sayı: 3, 159–166. https://ajindex.com/articles/438115

References (2)

  1. Leonard BE. Subtypes of serotonin receptors: biochecemical changes and pharmacological consequences. Int. Clin. Phychopharmacol 1992; 7: 13-21 2-Shukla R. Platelet H ketanserin Binding in Tension type headache. 43,103-110,2003 3-Lance JW. History of involvement of 5 HT in primary headaches. In olesen J, Saxena PR (eds). 5 HT mechanisms in primary headaches. New York: Raven Press, 1992, pp. 19-28 4-Hgrdisty RM, Stacey RS: 5 hydroxy tryptamine in normal platelets. J. Physiol. 130:711-20, 1995. 5-Somerville BM: Platelet bound and free serotonin levels in jugular and forearm venous bloodduring migraine, Neurology 26:41-45,1976 6-Thompson C.B., Jakubowsh J.A.:Platelet size and age determine platelet function independently. Blood 63: 1372-1375;1984 7-Martin J.F. The relationship between megakaryocyte pfoidy and platelet volume. Blood Cells. 15: 108-117:1989 8-Martin JF, Trowbridge EA. The biological significance of platelet volume; its relationship to bleeding time. Tromb Res. 32:443-460;1983 9-Joseph R, Welch KM A. Serotonerjic hypofunction in migraine. Cephalalgia 9: 193-199, 1989. 10-Stephen D, Silberstein MD. Serotonin and migraine. Headache 1994; 34; 408-417. 11-Schonen J,Maartensde Noordhout.Plasma catecholamines in headache patients. Cephalalgia 5 ( suppl 3) 28-9,1985. 12-Branimir J, Anton V.Platelet Serotonin Measures in Migraine. Headache.42:588-61; 2002 13-Joseph R, Welch KMA: Serotonerjic hypofunction in migraine. Cephalalgia 9: 193-199, 1989. 14-Schonen J, Maartens de Noordhout. Plasma catecholamines in headache patients. Cephalalgia 5 ( suppl 3) 28-9,1985. 15-Sicuteri F. Vazo nevroactive sustances and their implication in vascular pain. Rasarch and Clinical Studies in Headache, 1,6-45, 1967. 16-Ferrari MD, Odink J. Serotonin metabolism in migraine. Neurology 1989; 39: 1239-1242. 17-Ferrari MD, Saxeno PR. Serotonin and migraine. A clinical and pharmalogical review. Cephalalgia 1993; 13: 151-165. 18-Olsson JE: Neurologic finding in basillar migraine. Laryngoscope, 1991 101;1-40. 19-Anthony M, Hinterberger H. Plasma serotonin in migraine and stress. Archives of Neurology.1967,16, 544-592. 20-Ferrari MD, Frolich M.; Methionine - enkephalin and serotonin in migraine and tension headache. In Current problems in Neurology, 1987 vol 4, pp 227-34,
  2. John Libbey, London. 21-Anthony M, Hinterberger H. The possible relationship of serotonin to the migraine syndorme. Resarch and Clinical studies in Headache, 1969, 2 29-59 22-Dvilonsky A, Rishpon