Journals / Anadolu Kardiyoloji Dergisi / 2001 / Cilt: 1 - Sayı: 1

The relation of coronary artery disease with Doppler flow velocity and resistance index in cases without significant carotid artery stenosis

Anlamlı karotid arter darlığı olmayan olgularda Doppler akım hızları ve rezistans indekslerinin koroner arter hastalığı ile ilişkisi

Pages
5–9
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results suggest that presence and extent of CAD changes flow velocities and RI values of common and internal carotid arteries.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Atherosclerosis causes functional vasomotor changes as well as well as atheromatous carotid plaques and luminal stenosis resulting in mechanical effect.
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Key Findings & Data:In our study, the probable relationship between carotid arterial flow velocities and resistance indexes (RI) with the extent of coronary artery disease (CAD) in patients who do not have significant carotid luminal stenosis was evaluated.
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Conclusion & Impact:The results suggest that presence and extent of CAD changes flow velocities and RI values of common and internal carotid arteries.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Atherosclerosis causes functional vasomotor changes as well as well as atheromatous carotid plaques and luminal stenosis resulting in mechanical effect. The relation between functional vasomotor changes in carotid arteries and extent of coronary artery disease is unknown. In our study, the probable relationship between carotid arterial flow velocities and resistance indexes (RI) with the extent of coronary artery disease (CAD) in patients who do not have significant carotid luminal stenosis was evaluated. METHODS: One hundred and fourteen patients (74 males, mean age 53+/-10 years, range 33-72 years) were studied. All patients underwent color Doppler sonography before coronary angiography. Peak systolic flow velocity, end-diastolic flow velocity and resistance index (RI) of right and left common carotid and internal carotid and internal carotid arteries were measured by color Doppler sonographic technique. Doppler parameters were correlated with the extent of CAD and left ventricular ejection fraction. RESULTS: Patients were classified on the basis of presence of significant CAD and the number of affected coronary arteries. Thirty-three patients did not have (normal group) and 81 patients had significant coronary arterial stenosis (22 patients with one-vessel disease, 27, with two-vessel disease and 32 patients with three-vessel disease). Flow velocities were the highest in normal group but the lowest in CAD patients, especially when 3 coronary arteries were affected. Correlation analysis demonstrated negative relationship of age, ejection fraction and number of affected coronary arteries with end-diastolic flow velocity, but positive and significant correlation with RI value. CONCLUSION: Our study is the first on this object. The results suggest that presence and extent of CAD changes flow velocities and RI values of common and internal carotid arteries. However, further investigations are required before these parameters can be applied as diagnostic criteria.

Özet

Amaç: Bu çalışmada anlamlı karotid arter darlığı olmayan olgularda karotid arter akım hızları ve rezistans indeksleri (RI) ile koroner arter hastalığı (KAH) arasındaki olası ilişki araştırılmıştır. Yöntem: Çalışma KAH ön tanısı ile koroner anjiografi yapılan 74'ü erkek olan 114 olgu (yaş ortalaması 53Æ10, yaş aralığı 33-72) üzerinde yapıldı. Anjiografi öncesi sağ, sol ana karotid arterler (sağ-sol CCA) ve sağ, sol internal karotid arterler (sağ-sol ICA) akım hızları ve RI Doppler ultrasonografi (US) ile ölçüldü. Olgular KAH varlığı ve hastalıklı koroner arter sayısına göre gruplandırılarak Doppler parametreleri ve ejeksiyon fraksiyonu (EF) yönünden karşılaştırıldı. Bulgular: Otuz üç olguda koroner arterlerde daralma saptanmazken (normal grup), 81 olguda anlamlı koroner arter darlığı saptandı (22 olguda bir arterde, 27 olguda iki arterde ve 32 olguda üç koroner arterde). Akım hızları Kah olan grupta anlamlı olarak daha düşük, RI ise daha yüksek bulundu. Akım hızları normal grup;ta en yüksek 3 damar hastalığı (DH) olan grupta en düşüt.ü RI ise normal grupta en düşük iken 3 DH olan grupta en yüksekti. Korelasyon analizinde yaş, EF ve hastalıklı damar sayısı ile özellikle minimal akım hızları arasında ters, RI değerleri arasında doğru ve anlamlı korelasyon saptandı. Sonuç: Bu çalışma bu konu ile ilgili ilk çalışma olup elde edilen bulgular; KAH varlığı ve aterosklerozun yaygınlığının Doppler US ile ölçülen CCA, ICA akım hızları ve RI değerlerini değiştirdiğini düşündürmektedir.

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Cite This Article

ÜLGEN, M. S., BİLİCİ, A., ACAR, M., SUCU, M., ÖNDER, H., TOPRAK, N. (2022). The relation of coronary artery disease with Doppler flow velocity and resistance index in cases without significant carotid artery stenosis. Anadolu Kardiyoloji Dergisi, Cilt: 1 - Sayı: 1, 5–9. https://ajindex.com/articles/437589

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References (13)

  1. Mathur KS, Kashyap SK, Kumar V. Correlation of the extent and severity of atherosclerosis in the coronary and cerebral arteries. Circulation 1963; 27: 293-31
  2. Crouse JR, Toole JF, McKinney VM, et al. Risk factors for extra cranial carotid artery atherosclerosis. Stroke 1987; 18: 990-6
  3. Wofford JL, Kahl FR, Howard GR, et al. Relation of extentet of extracranial carotid artery atherosclerosis as measured by B-mode ultrasound to extent of coronary atherosclerosis. Arteriosci Thromb 1991; 11: 1786-94
  4. Lieberman EH, Gerhard MD, Uehata A, et al. Flow-induced vasodilyatatiton of the human brachial artery is impaired in patients _____40 years of age with coronary artery disease. Am J Cardiol 1996; 78: 1210-14
  5. Sanguigni V, Gallu’ M, Strano A. Incidence of carotid arteriosclerosis in patients with coronary artery disease. Angiology 1993; 44: 34-8
  6. Humphries JO, Kuller L, Ross RS, Friesinger C, Page EE. Natural history of ischemic heart disease in relation to arteriographic findings. Circulation 1974; 49: 489-97
  7. Craven TE, Ryu JE, Espeland MA, et al. Evaluation of the associations between carotid artery atherosclerosis and coronary artery stenosis. Circulation 1990; 82: 1230-42
  8. Salonen JT, Salonen R. Ultrasonographically assessed carotid morphology and the risk of coronary heart disease. Ateroscler Thromb. 1991; 11: 1245-49
  9. Sutton-Tyrell K, Wolfson SK Jr, Kuller LH. Blood pressure treatment slows the progression of carotid stenosis in patients with isolated systolic hypertension. Stroke. 1994; 25: 44-50
  10. Isii T, Wevman WP, Guzman MA, et al. Coronary and aortic atherosclerosis in young men from Tokyo and New Orleans. Lab Invest 1986; 54: 561-5
  11. Hayashi K, Handa H, Nagasawa S, Okumura A, Moritake K. Stiffness and elastic behaviour of human intracranial and extracranial arteries. J Biomechanics 1980; 13: 175-84
  12. Hirai T, Sasayama S, Kawasaki T, Yagi S. Stiffness of systemic arteries in patients with myocardial infarction. A non-invasive method to predict severity of coronary atherosclerosis. Circulation 1989; 80: 78-86
  13. Landwehr P. Basic Hemodynamics. Color Duplex Sonography Thieme Medical Publishers. New York. 1995; p. 32.