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Journals / Anadolu Kardiyoloji Dergisi / 2007 / Cilt: 7 - Sayı: 3

Wegener granülomatozu’nda karotis-femoral nabız dalga hızı ile belirlenen arteryel genişleyebilirlik

Arterial distensibility in Wegener’s granulomatosis: a carotid - femoral pulse wave velocity study

Mustafa YILDIZ
Mehmet SOY
Turhan KÜRÜM
Banu Şahin YILDIZ
Pages
281–285
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Measurements of carotid-femoral (aortic) PWV may provide an easy and noninvasive technique to identify patients at increased risk of arterial disease. (Anadolu Kardiyol Derg 2007; 7: 281-5)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The purpose of this study was to test the hypothesis; that chronic inflammation may impair vascular function and lead to an increase of arterial pulse wave velocity (PWV) in patients with Wegener’s granulomatosis (WG).Methods: We recruited 5 patients with WG and 5 healthy age and sex matched controls in this cross-sectional case-controlled study.
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Key Findings & Data:Aortic PWV was determined by using an automatic device (Complior Colson, France), which allowed on-line pulse wave recording and automatic calculation of PWV.Results: The carotid-femoral (aortic) PWV was increased in patients with WG as compared with control group (p=0.04).
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Conclusion & Impact:Measurements of carotid-femoral (aortic) PWV may provide an easy and noninvasive technique to identify patients at increased risk of arterial disease. (Anadolu Kardiyol Derg 2007; 7: 281-5)
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The purpose of this study was to test the hypothesis; that chronic inflammation may impair vascular function and lead to an increase of arterial pulse wave velocity (PWV) in patients with Wegener’s granulomatosis (WG).Methods: We recruited 5 patients with WG and 5 healthy age and sex matched controls in this cross-sectional case-controlled study. Aortic PWV was determined by using an automatic device (Complior Colson, France), which allowed on-line pulse wave recording and automatic calculation of PWV.Results: The carotid-femoral (aortic) PWV was increased in patients with WG as compared with control group (p=0.04). Although we found positive correlation between PWV and heart rate (r=0.75, p=0.01), we did not find any significant correlation between PWV and anthropometric and other hemodynamic parameters (p>0.05). In addition, we found positive correlation between PWV and erythrocyte sedimentation rate in patients with WG (r=0.90, p=0.03).Conclusion: Pulse wave velocity is increased and arterial distensibility decreased in patients with WG. Measurements of carotid-femoral (aortic) PWV may provide an easy and noninvasive technique to identify patients at increased risk of arterial disease. (Anadolu Kardiyol Derg 2007; 7: 281-5)

Özet

Amaç: Çalışmanın amacı, kronik enflamasyon Wegener granülomatoz (WG)’lu hastalarda vasküler fonksiyonları bozup arteryel nabız dalga hızı (NDH)’nı artırabilir, hipotezini araştırmaktır.Yöntemler: Yaş ve cinsiyet olarak uyumlu 5 WG’lu hasta ve 5 sağlıklı kontrol grubu çalışmaya dahil edildi. Aortik NDH, on-line nabız dalga kaydına izin veren ve otomatik ölçüm yapan Complior Colson (Fransa) cihazı ile belirlendi.Bulgular: Karotis-femoral (aortik) NDH kontrol grubuna göre WG’lu hastalarda daha yüksek bulundu (p=0.04). Nabız dalga hızı ve kalp hızı arasında pozitif yönde korelasyon saptarken (r=0.75, p=0.01), NDH ile antropometrik ve diğer hemodinamik değişkenler arasında anlamlı korelasyon izlemedik (p>0.05). Ek olarak WG’lu hastalarda, NDH ve sedimantasyon arasında pozitif korelasyon saptadık (r=0.90, p=0.03). Sonuç: Wegener granülomatoz’lu hastalarda NDH artmış arteryel genişleyebilirlik azalmıştır. Karotis-femoral (aortik) NDH artmış arteryel hastalık riski olan hastaların teşhisinde kolay ve non-invazif bir teknik olabilir. (Anadolu Kardiyol Derg 2007; 7: 281-5)

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Cite This Article

YILDIZ, M., SOY, M., KÜRÜM, T., YILDIZ, B. Ş. (2022). Wegener granülomatozu’nda karotis-femoral nabız dalga hızı ile belirlenen arteryel genişleyebilirlik. Anadolu Kardiyoloji Dergisi, Cilt: 7 - Sayı: 3, 281–285. https://ajindex.com/articles/437143

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