Journals / Anadolu Kardiyoloji Dergisi / 2007 / Cilt: 7 - Sayı: 2

Koroner arter hastalığı gelişiminde majör risk faktörlerinin birbirleri arasındaki ilişkilerinincelenmesi: Bir sınıflandırma ağacı yaklaşımı

Analysis of intervariable relationships between major risk factors in the development of coronary artery disease: a classification tree approach

Pages
140–145
Publication Date
2022-10-10
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Sorting the major risk factors of CAD from the most to least according to the classification importance was resulted as sex, age, diabetes mellitus, hypercholesterolemia, family history of CAD and smoking status.

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Objective & Hypothesis:Objective: The purpose of this study is to determine how the major risk factors are related to each other in the development of coronary artery disease (CAD) using Chi-squared Automatic Interaction Detection (CHAID).Methods: All patients with suspected CAD seen in the cardiology clinic between January 1999 and February 2003 who underwent coronary angiography were included in the study.
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Key Findings & Data:A retrospective analysis was performed in 1381 patients.
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Conclusion & Impact:Conclusion: Sorting the major risk factors of CAD from the most to least according to the classification importance was resulted as sex, age, diabetes mellitus, hypercholesterolemia, family history of CAD and smoking status.
🔬Design:Modeling & Simulation
📍Scope:2003 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The purpose of this study is to determine how the major risk factors are related to each other in the development of coronary artery disease (CAD) using Chi-squared Automatic Interaction Detection (CHAID).Methods: All patients with suspected CAD seen in the cardiology clinic between January 1999 and February 2003 who underwent coronary angiography were included in the study. A retrospective analysis was performed in 1381 patients. In all patients’ sex, age, type II diabetes mellitus, hypercholesterolemia, systemic hypertension, smoking status, family history of CAD, body mass index (BMI) were assessed. Results: According to classification tree, first-level split produced the two initial branches: female (unadjusted presence percentage = 48.07%) versus male (unadjusted presence percentage = 78.02%). For the male aged between 49-81 years and the female aged between 15-48, 49-60 and 61-71 years, diabetes mellitus was the most prominent risk factor. However, hypercholesterolemia was the best predicting variable for the females aged between 72-81 years. For the females of 15-48 years and 49-60 years age categories without diabetes mellitus, smoking status and family history of CAD had important contribution to the model. Conclusion: Sorting the major risk factors of CAD from the most to least according to the classification importance was resulted as sex, age, diabetes mellitus, hypercholesterolemia, family history of CAD and smoking status.

Özet

Amaç: Bu çalışmanın amacı, koroner arter hastalığının (KAH) gelişmesine etki ettiği bilinen majör risk faktörlerinin bir birleri ile ilişkilerinin nasıl olduğunu “Chi-squared Automatic Interaction Detection” (CHAID) metodu kullanarak belirlemektir. Yöntemler: Ocak 1999-Şubat 2003 yılları arasında kardiyoloji kliniğinde KAH’dan şüphelenilen ve koroner anjiyografisi yapılan bütün hastalar çalışmaya alınmıştır. Geriye dönük araştırma 1381 hasta üzerinde yapılmıştır. Bütün hastalar için cinsiyet, yaş, tip II diyabet, hiperkolesterolemi, sistemik hipertansiyon, sigara kullanımı, ailede KAH olma, vücut kitle indeksi kullanıldı. Bulgular: Sınıflandırma ağacında, birinci bölünmeyle iki başlangıç dal meydana geldi: kadınlarla erkeklerin düzeltilmemiş KAH olma yüzdesi sırasıyla %48.07 ve %78.02 bulundu. Yaşı 49-81 arasında olan erkekler ve yaşı 15-48, 49-60 ve 61-71 arasında olan kadınlarda diyabet en önemli faktör olarak bulundu. Bununla birlikte, hiperkolesterolemi, yaşı 72-81 arasında olan kadınlar için en iyi kestirici olarak bulundu. Yaşı 15-48 ve 49-60 arasında olan diyabetsiz kadınlar için sigara kullanımı ve ailede KAH olma kestirici değişkenlerinin modele önemli katkıları olduğu görüldü. Sonuç: Bu çalışmada, KAH riski üzerine etkisi olan faktörler sınıflandırma önemine göre cinsiyet, yaş, diyabet, hiperkolesterolemi, ailesinde KAH olma ve sigara kullanımı şeklinde sıralanmıştır.

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Cite This Article

TÜRE, M., KURT, İ., KÜRÜM, T. (2022). Koroner arter hastalığı gelişiminde majör risk faktörlerinin birbirleri arasındaki ilişkilerinincelenmesi: Bir sınıflandırma ağacı yaklaşımı. Anadolu Kardiyoloji Dergisi, Cilt: 7 - Sayı: 2, 140–145. https://ajindex.com/articles/437121

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