Journals / Anadolu Kardiyoloji Dergisi / 2008 / Cilt: 8 - Sayı: 2

Akut anterior miyokard enfarktüsünde sağ dal bloğunun klinik ve anjiyografik önemi

Clinical and angiographic importance of right bundle branch block in the setting of acute anterior myocardial infarction

Pages
123–127
Publication Date
2022-10-10
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Culprit lesion in patients with RBBB is more commonly a LAD proximal lesion and threatened myocardial tissue is larger in patients with RBBB.

📌 3 Key Takeaways

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Objective & Hypothesis:To investigate functional status of patients (Killip class), left ventricular contractility, angiographic anatomy and severity of coronary lesions in patients with and without right bundle branch block (RBBB) in the setting of anterior myocardial infarction (MI).
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Key Findings & Data:Methods: Patients who admitted to coronary care unit with the diagnosis of acute anterior MI between 1999 and 2005 were retrospectively searched from our database.
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Conclusion & Impact:Culprit lesion in patients with RBBB is more commonly a LAD proximal lesion and threatened myocardial tissue is larger in patients with RBBB.
🔬Design:Research Article
📍Scope:2005 Verileri
⚙️Variables:Domain Parameters

Abstract

To investigate functional status of patients (Killip class), left ventricular contractility, angiographic anatomy and severity of coronary lesions in patients with and without right bundle branch block (RBBB) in the setting of anterior myocardial infarction (MI). Methods: Patients who admitted to coronary care unit with the diagnosis of acute anterior MI between 1999 and 2005 were retrospectively searched from our database. Out of 792 patients, 37 had RBBB (RBBB group) either at admission or in the course of anterior MI. Forty patients who developed no intraventricular conduction defect during the course of anterior MI with the same demographic characteristics were selected as the control group. Results: Out of 37 patients, 30 had RBBB on admission and 7 developed RBBB in the course of acute MI. Left anterior descending artery (LAD) proximal lesion was more commonly detected in the RBBB group [23 (62.2%) vs. 11 (27.5%) patients, p=0.003]. Left ventricular ejection fraction was lower (33.0±4.2% vs 36.7±4.9%, p=0.003) and end-systolic volume was higher (84.1±24.9 ml vs 74.6±22.0 ml, p=0.012) in patients with RBBB. Number of patients with high Killip grade (III and IV) was more in the RBBB group [7 (18.9%) vs 3 (7.5%), RR: 1.75, %95 CI 0.92-3.32, p=0.14], and number of patients with Killip grade I was more in the control group [34 (85.0%) vs 22 (59.5%), p=0.012]. Besides mean Killip class was higher in the RBBB group (1.65±0.90 vs 1.25±0.67, p=0.03). Three patients (8.1%) in the RBBB group and 2 patients (5.0%) in the control group died during hospitalization (p=0.67). Conclusion: Left ventricular ejection fraction decreases and Killip grade increases in case of RBBB in the setting of acute anterior MI. Culprit lesion in patients with RBBB is more commonly a LAD proximal lesion and threatened myocardial tissue is larger in patients with RBBB.

Özet

Akut anterior miyokard infarktüsü (MI) ile sağ dal bloğu (RBBB) birlikteliğinde hastaların fonksiyonel durumunu (Killip sınıflaması), sol ventrikül kontraktilitesini, anjiyografik anatomiyi ve koroner lezyon ciddiyetini değerlendirmek. Yöntemler: Akut anterior MI tanısı ile 1999-2005 yılları arasında koroner yoğun bakım ünitesine yatırılan 792 hasta retrospektif olarak tarandı. Bu hastaların 37’sinde başvuru elektrokardiyogramlarında (EKG) ya da takiplerinde RBBB izlenmişti (RBBB grubu). Akut anterior MI seyrinde intraventriküler ileti defekti bulunmayan benzer demografik özelliklere sahip 40 hasta ise kontrol grubu olarak çalışmaya alındı. Bu hastaların koroner anjiyografi ile ekokardiyografi bulguları, Killip sınıflaması ve hastane içi mortaliteleri araştırıldı. Bulgular: Otuz yedi hastanın 30’unun başvuru EKG’sinde RBBB mevcuttu. Geri kalan 7’sinde ise takipte RBBB gelişmişti. Sağ dal bloğu grubunda infarktüsten sorumlu lezyon sol ön inen (LAD) arterde daha proksimalde bir lezyondu (23 [%62.2]’e karşın 11 [%27.5], P=0.003). Sol ventrikül ejeksiyon fraksiyonu RBBB grubunda daha düşükken (%33.0±4.2’e karşın %36.7±4.9, p=0.003) sol ventrikül sistol sonu çapı daha yüksekti (84.1±24.9 ml karşın 74.6±22.0 ml, p=0.012). İstatistiksel olarak anlamlı olmasa da yüksek Killip sınıfı olan hastalar (Killip sınıf III ve IV) RBBB grubunda daha fazla sayıdaydı (7’ye karşın 3, RR: 1.75, %95 CI 0.92-3.32, p=0.14) aksine Killip sınıfı I olan hasta sayısı kontrol grubunda anlamlı oranda daha fazlaydı (22’ye karşın 34, RR: 0.80, %95 CI 0.62-1.03, P = 0.029). Ayrıca RBBB grubunda ortalama Killip sınıfı daha yüksekti (1.65±0.90’a karşın 1.25±0.67, P=0.03). Sağ dal bloğu grubundaki 3 (%8.1) hasta ve kontrol grubundaki 2 (%5.0) hasta hastanedeki takibi esnasında eksitus oldu (p=0.67). Sonuç: Akut anterior MI ve RBBB birlikteliğinde ejeksiyon fraksiyonu düşmektedir ve Killip sınıfı artmaktadır. Bu hastalarda infarktüs ile ilişkili lezyon sıklıkla LAD proksimal lezyonudur, dolayısıyla daha geniş bir miyokard alanı tehdit altındadır.

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Cite This Article

BALCIOĞLU, S., TAVİL, Y., ÇENGEL, A., ÖZDEMİR, M., ARSLAN, U. (2022). Akut anterior miyokard enfarktüsünde sağ dal bloğunun klinik ve anjiyografik önemi. Anadolu Kardiyoloji Dergisi, Cilt: 8 - Sayı: 2, 123–127. https://ajindex.com/articles/437097

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