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Journals / Anadolu Kardiyoloji Dergisi / 2008 / Cilt: 8 - Sayı: 4

Ailevi Akdeniz ateşinde aortik sertleşme parametrelerinin ve ventrikül fonksiyonlarının değerlendirilmesi

Assessment of aortic stiffness and ventricular functions in familial Mediterranean fever

Gerçek CAN
İsmail SARI
Mehmet TUNCA
Özlem ARICAN
Bahri AKDENİZ
Fatoş ÖNEN
Merih BİRLİK
Nurullah AKKOÇ
Servet AKAR
Sema GÜNERİ
Pages
271–278
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Tricuspid annular plane systolicexcursion (TAPSE) was significantly reduced in FMF group than in controls [2 (1.3-2.5) vs. 2.5 (1.7-3.2) cm; p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To investigate systolic and diastolic ventricular functions, aortic elastic properties and the presence of pericardial effusion in familial Mediterranean fever (FMF) patients.Methods: A case-controlled, cross-sectional study was performed on 44 FMF patients and 27 controls.
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Key Findings & Data:Results: Age, sex, body mass index, smoking status and lipids were comparable in patients and controls (p>0.05).
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Conclusion & Impact:Tricuspid annular plane systolicexcursion (TAPSE) was significantly reduced in FMF group than in controls [2 (1.3-2.5) vs. 2.5 (1.7-3.2) cm; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To investigate systolic and diastolic ventricular functions, aortic elastic properties and the presence of pericardial effusion in familial Mediterranean fever (FMF) patients.Methods: A case-controlled, cross-sectional study was performed on 44 FMF patients and 27 controls. Subjects with hypertension, diabetesmellitus and hyperlipidemia were excluded. Left and right ventricular functions were measured using echocardiography including two-dimensional, M-mode, and conventional Doppler as well as pulsed wave tissue Doppler imaging (TDI). Aortic elasticity was analyzed using M-mode tracing guided by the two-dimensional echocardiography. Statistical analysis was performed using Mann Whitney U, Spearman rho correlation and Fisher's exact tests. Results: Age, sex, body mass index, smoking status and lipids were comparable in patients and controls (p>0.05). None of the subjects hadpericarditis and/or pericardial effusion. Aortic wall properties were similar between groups (p>0.05). The TDI parameters of mitral lateral annulus revealed significantly lower Em/Am ratios in patients compared to controls [1.77 (0.6-3.4) vs. 1.79 (0.9-4.8), p=0.02]. Mitral flow propagationvelocity was significantly lower in patients than healthy subjects [63 (39-100) vs. 74 (40-94) cm/s, p=0.008]. Tricuspid annular plane systolicexcursion (TAPSE) was significantly reduced in FMF group than in controls [2 (1.3-2.5) vs. 2.5 (1.7-3.2) cm; p

Özet

Amaç: Bu çalışmada Ailevi Akdeniz Ateşi (AAA) hastalarında aortun elastik özelliklerinin, ventrikül fonksiyonlarının ve perikardiyal efüzyon varlığının değerlendirilmesini amaçladık. Yöntemler: Bu vaka-kontrollü, enine-kesitsel çalışmada 44 AAA hastası ve 27 sağlıklı birey yer aldı. Hipertansiyon, diyabet ve dislipidemisi olan bireyler çalışmaya alınmadı. Sağ ve sol ventrikül fonksiyonlarının değerlendirilmesinde 2-boyutlu, M-mod, standart ve doku Doppler ekokardiyografi incelemeleri kullanıldı. Aortun elastik özelliklerinin incelenmesinde 2-boyutlu ve M-mod ekokardiyografi kullanıldı. İstatistiksel değerlendirmede Mann Whitney U, Fisher testi ve Spearman korelasyonu kullanıldı. Bulgular: Hasta ve kontrol grubu yaş, cins, sigara kullanma durumu, vücut kitle indeksi- ve serum lipid düzeyleri açısından benzer özellikteydi (p>0.05). Çalışma grubundaki hiçbir bireyde perikardit ve/veya perikardiyal efüzyonla ilişkin bulguya rastlanmadı. Aortik elastik fonksiyon parametreleri hasta ve kontrol gurupları arasında benzerdi (p>0.05). Doku Doppler ile elde edilen sol ventrikül mitral annuler Em/Am oranı hasta grubunda kontrollere göre anlamlı olarak düşüktü [1.77 (0.6-3.4) karşı 1.79 (0.9-4.8) p=0.02]. Öte yandan mitral renkli M-mod akım yayılma hızı (Vp) hasta grubunda anlamlı olarak kısa bulundu [63 (39-100) karşı 74 (40-94) cm/s, p=0.008]. Triküspid annuler düzlem sistolik hareketi (TAPSE) değeri AAA hastalarında kontrollere göre belirgin düşüktü [2 (1.3-2.5) vs. 2.5 (1.7-3.2) cm; p

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Cite This Article

CAN, G., SARI, İ., TUNCA, M., ARICAN, Ö., AKDENİZ, B., ÖNEN, F., BİRLİK, M., AKKOÇ, N., AKAR, S., GÜNERİ, S. (2022). Ailevi Akdeniz ateşinde aortik sertleşme parametrelerinin ve ventrikül fonksiyonlarının değerlendirilmesi. Anadolu Kardiyoloji Dergisi, Cilt: 8 - Sayı: 4, 271–278. https://ajindex.com/articles/437025

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