Journals / Anadolu Kardiyoloji Dergisi / 2008 / Cilt: 8 - Sayı: 2

Global confusion on the diagnostic criteria for metabolic syndrome: what is the point that guidelines can not agree?

Metabolik sendrom tanı kriterleri hakkında yaşanan küresel kargaşa: kılavuzların anlaşamadığı nokta nedir?

Pages
149–153
Publication Date
2022-10-10
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Maintenance of the metabolic syndrome as a diagnostic category would still seem to be useful for an effective multiple cardiovascular risk prediction.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Several international and national associations have proposed their own diagnostic criteria for metabolic syndrome.
📊
Key Findings & Data:Diagnostic or definitive components of the syndrome (i.e., obesity, insulin resistance) should be considered separately from the associated-conditions (i.e., polycystic ovary, obstructive sleep apnea, microalbuminuria, non-alcoholic steatohepatitis etc.) of metabolic syndrome, during the course of diagnosis.
💡
Conclusion & Impact:Maintenance of the metabolic syndrome as a diagnostic category would still seem to be useful for an effective multiple cardiovascular risk prediction.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Several international and national associations have proposed their own diagnostic criteria for metabolic syndrome. Regarding the heterogeneity of these guidelines, some authors refused the usage of metabolic syndrome definition. Here we aimed to analyze the differences between the diagnostic criteria proposed for metabolic syndrome. We reviewed and compared these different guidelines’ criteria. We conclude that, despite the heterogeneity, there is a conceptual agreement on the definition of metabolic syndrome. But cut-off values and selection of diagnostic parameters are still conflicting. Diagnostic or definitive components of the syndrome (i.e., obesity, insulin resistance) should be considered separately from the associated-conditions (i.e., polycystic ovary, obstructive sleep apnea, microalbuminuria, non-alcoholic steatohepatitis etc.) of metabolic syndrome, during the course of diagnosis. Maintenance of the metabolic syndrome as a diagnostic category would still seem to be useful for an effective multiple cardiovascular risk prediction.

Özet

Pek çok ulusal ve uluslar arası dernek kendi metabolik sendrom tanı kriterlerini tanımlamıştır. Bu tanı kılavuzlarının çeşitliliği, bazı yazarları metabolik sendrom tanımından vazgeçilmesini savunmaya teşvik etmiştir. Bu makalede kılavuzların tanı kriterleri arasındaki farklılıkların irdelenmesi amaçlanmış, karşılaştırmalı olarak gözden geçirilmiştir. Görülmüştür ki, kılavuzların çeşitliliğine rağmen, aralarında kavramsal bir uyum söz konusudur. Fakat hangi değişkenlerle, hangi eşik değerler aşıldığında tanı konulacağı konusunda herhangi bir uyum mevcut değildir. Tanısal veya tanımlayıcı parametreler (obezite ve insülin direnci gibi) ile sendroma eşlik eden anormalliklerin (polikistik over, uyku apne sendromu, mikroalbuminüri, yağlı karaciğer gibi) birbirine karıştırılması, tanısal tasnifleri güçleştirmektedir. Çoklu kardiyovasküler riskle etkin mücadele için, tanısal bir kategori olarak metabolik sendrom tanımından vazgeçilmemesi gerekir.

🔖

Cite This Article

YILDIRIM, T., DAĞDELEN, S., ERBAŞ, T. (2022). Global confusion on the diagnostic criteria for metabolic syndrome: what is the point that guidelines can not agree?. Anadolu Kardiyoloji Dergisi, Cilt: 8 - Sayı: 2, 149–153. https://ajindex.com/articles/436977

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. National cholesterol education program (NCEP) Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults: Executive summary of the third report of the national cholesterol program (NCEP) Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult treatment panel III). JAMA 2001; 285: 2486-97
  2. Avogaro P, Crepaldi G, Enzi G, Tiengo A. Associazione di iperlipidemia, diabete mellito e obesita di medio grado. Acta Diabetol Lat 1967; 4: 36-41
  3. Haller H. Epidemiologie und assoziierte risikofaktoren der hyperlipoproteinamie (Epidemiology and associated risk factors of hyperlipoproteinemia). Z Gesamte Inn Med 1977; 32: 124-128
  4. Singer P. Zur diagnostik der primaren hyperlipoproteinamien (Diagnosis of primary hyperlipoproteinemias). Z Gesamte Inn Med 1977; 32: 129-39
  5. Ferrannini E, Haffner SM, Mitchell BD, Stern MP. Hyperinsulinaemia: the key feature of a cardiovascular and metabolic syndrome. Diabetologia 1991; 34: 416-22
  6. Reaven GM. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607
  7. Reaven GM. Syndrome X. Blood Pres Suppl 1992; 4: 13-16
  8. World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications: Report of a WHO Consultation. Part 1: Diagnosis and classification of diabetes mellitus. Geneva, Switzerland: World Health Organization: 1999. Available at: URL:
  9. Third report of the National Cholesterol Education Program (NCEP). Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults. (Adult Treatment Panel III). Final report. Circulation 2002; 106: 3143-241
  10. Einhorn D, Reaven GM, Cobin RH, Ford E, Ganda OP, Handelsman Y, et al. American college of endocrinology position statement on the insulin rezistance syndrome. Endocr Pract 2003; 9: 237-52
  11. Kanauchi M, Kanauchi K, Kimura K, Inoue T, Saito Y. Utility of elevated 2-hour postload plasma glucose as an alternative to elevated fasting glucose as a criterion for the metabolic syndrome. Metabolism 2006; 55: 1323-6
  12. The IDF consensus worldwide definition of the metabolic syndrome 2005. Available at: URL: http://www.idf.org/webdata/docs/ Metsyndrome_Final.pdf 13. Türkiye Endokrinoloji ve Metabolizma Derneği Metabolik Sendrom Kılavuzu. Available at: URL:
  13. Lanas F, Avezum A, Bautista LE, Diaz R, Luna M, Islam S, et a