Journals / Anadolu Kardiyoloji Dergisi / 2009 / Cilt: 9 - Sayı: 6

The effect of inhibition of renin-angiotensin system on cardioversion success and recurrences of atrial fibrillation

Atriyal fibrilasyonda renin-anjiyotensin sistem inhibisyonunun kardiyoversiyon başarısı ve nüksler üzerine etkisi

Pages
505–511
Publication Date
2022-10-10
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, we overview the effect of RAS blockers on cardioversion success and recurrence of AF.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The renin-angiotensin system (RAS) can play an important role as the underlying mechanism for the development and recurrence of atrial fibrillation (AF).
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Key Findings & Data:This remodeling serves as an arrhythmogenic substrate for AF.
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Conclusion & Impact:In this review, we overview the effect of RAS blockers on cardioversion success and recurrence of AF.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The renin-angiotensin system (RAS) can play an important role as the underlying mechanism for the development and recurrence of atrial fibrillation (AF). In addition, AF itself can lead to atrial structural and/or electrophysiologic remodeling by activating the RAS. This remodeling serves as an arrhythmogenic substrate for AF. Thus, the inhibition of RAS with angiotensin converting-enzyme inhibitor or angiotensin receptor blockers may be a strategy to prevent occurrence and recurrence of AF in certain patients such as those with heart failure and hypertension in associated with left ventricular hypertrophy. In addition, it may facilitate the cardioversion of AF. In this review, we overview the effect of RAS blockers on cardioversion success and recurrence of AF.

Özet

Atriyal fibrilasyon (AF) gelişmesi ve tekrarlamalarında, altta yatan mekanizma olarak renin-anjiyotensin sistemi (RAS) önemli rol oynayabilir. Ayrıca, AF’nin kendisi RAS’ı aktive ederek atriyal yapısal ve/veya elektrofizyolojik yeniden biçimlenmeye neden olabilir. Bu yeniden biçimlenme, AF için aritmojenik kaynak görevi görebilir. Bundan dolayı, kalp yetersizliği ve sol ventrikül hipertrofisinin eşlik ettiği hipertansiyon gibi belirli hastalarda, AF gelişmesini ve tekrarını önlemek için, anjiyotensin-dönüştürücü enzim inhibitörleri veya anjiyotensin reseptör blokerleriyle RAS’ın baskılanması bir tedavi yöntemi olabilir. Ayrıca, RAS’ın baskılanması, AF kardiyoversiyonunu iyileştirebilir. Bu yazıda, RAS blokerlerinin, AF’nin kardiyoversiyonu ve nükslerine etkisini gözden geçirdik.

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Cite This Article

AKÇAY, S., DOĞAN, A. (2022). The effect of inhibition of renin-angiotensin system on cardioversion success and recurrences of atrial fibrillation. Anadolu Kardiyoloji Dergisi, Cilt: 9 - Sayı: 6, 505–511. https://ajindex.com/articles/436920

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