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Journals / Anadolu Kardiyoloji Dergisi / 2009 / Cilt: 9 - Sayı: 2

Fibromyalji sendromu saptanan kadın hastalarda otonomik fonksiyon bozuklukları ve günlük otonomik değişimler ile aritmi sıklığı arasındaki bağıntılar

Correlations between autonomic dysfunction and circadian changes and arrhythmia prevalence in women with fibromyalgia syndrome

Mehmet Tolga DOĞRU
Aliye TOSUN
Gülümser AYDIN
Haksun EBİNÇ
Ayşe ARSLAN
Sevim ORKUN
Işık KELEŞ
Mahmut GÜNERİ
Pages
110–117
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The low frequency/HF ratio (LF/HF) values for total 24 hours (2.22±0.18 vs. 1.22±0.12, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: It is known that increased sympathetic activity and decreased parasympathetic activity are present in patients with fibromyalgia syndrome (FMS).
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Key Findings & Data:Methods: Fifty female patients with FMS and 30 healthy female controls were included in this cross-sectional, case-controlled study.
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Conclusion & Impact:The low frequency/HF ratio (LF/HF) values for total 24 hours (2.22±0.18 vs. 1.22±0.12, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: It is known that increased sympathetic activity and decreased parasympathetic activity are present in patients with fibromyalgia syndrome (FMS). This study aims to investigate the correlations of autonomic dysfunction and differences in autonomic circadian activity with arrhythmia prevalence in women with FMS. Methods: Fifty female patients with FMS and 30 healthy female controls were included in this cross-sectional, case-controlled study. A 12-lead electrocardiogram and 24-hour Holter monitoring were performed in all patients to evaluate arrhythmias and autonomic function tests. Heart rate variability (HRV) parameters were utilized to detect autonomic dysfunction in patients with FMS. HRV measurements were performed in total 24-hour, day time (06:00-22:59), night time (23:00-05:59) periods and during autonomic tests (stand - supine, inspiration-expiration and Valsalva tests) using 24-hour Holter monitoring recordings. Student t-test , Mann–Whitney U and Pearson Chi-square tests were used for comparisons of the data between groups. The correlation of data was tested by using Spearman correlation analysis.Results: The mean ages of the patient and control groups were 38±7.4 and 36±8.1 years, respectively. In HRV measurements, high frequency (HF) power, was significantly decreased in the patient group as compared with control group (167.4 msec2 (107.0- 312.0) vs.314.5 msec2 (124.0- 905.0), p=0.017). The low frequency/HF ratio (LF/HF) values for total 24 hours (2.22±0.18 vs. 1.22±0.12, p

Özet

Amaç:Fibromiyalji sendromu (FMS) bulunan hastalarda artmış sempatik ve azalmış parasempatik aktivitenin varlığı bilinmektedir. Bu çalışma FMS bulunan kadın hastalarda otonomik disfonksiyon ve günlük otonomik aktivite değişimleri ile aritmi sıklığının araştırılmasını amaçlamaktadır. Yöntemler: Elli FMS bulunan ve 30 sağlıklı kadın (kontrol) enine-kesitli ve vaka kontrollü bu çalışmaya alındı. Her hastaya, otonom sınır sistemi ve aritmi analizi amacı ile 12 kanallı elektrokardiyografi ve 24 saatlik Holter takibi yapıldı. Kalp atım hızı değişkenliği parametreleri 24 saat, gündüz (06:00-22:59) ve gece (23:00-05-59) ve yapılan otonomik testlere (ayağa kalkış ve yatış, nefes alma ve verme ve Valsalva testleri) ait zaman aralıklarında 24 saat Holter takip kayıtları kullanılarak ölçüldü. İstatistiksel değerlendirmede verilerin karşılaştırılmasında Student t, Mann-Whitney U ve Pearson Ki-kare testleri kullanıldı. Veriler arasındaki korelasyonun tespiti için Spearman korelasyon analizi kullanıldı.Bulgular: Hasta ve kontrol gruplarının ortalama yaşları sırasıyla 38±7.4 ve 36±8.1 idi. Kalp atım hızı değişkenliği ölçümlerinde yüksek frekans (YF) kuvveti hasta grubunda önemli ölçüde düşük olarak bulundu [167.4 msn2 (107.0- 312.0) karşı 314.5 msn2 (124.0- 905.0), p=0.017). Düşük frekans (DF) / YF oranı (DF/YF) 24 saatlik dönem için (2.22±0.18’e karşı 1.22±0.12, p

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Cite This Article

DOĞRU, M. T., TOSUN, A., AYDIN, G., EBİNÇ, H., ARSLAN, A., ORKUN, S., KELEŞ, I., GÜNERİ, M. (2022). Fibromyalji sendromu saptanan kadın hastalarda otonomik fonksiyon bozuklukları ve günlük otonomik değişimler ile aritmi sıklığı arasındaki bağıntılar. Anadolu Kardiyoloji Dergisi, Cilt: 9 - Sayı: 2, 110–117. https://ajindex.com/articles/436899

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