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Journals / Anadolu Kardiyoloji Dergisi / 2010 / Cilt: 10 - Sayı: 2

Zahedan Çocuk ve Genç Sağlığı Araştırma Merkezindeki 5-10 yaşlarındaki beta-talasemi majörü olan hastalarda sistolik ve diyastolik kalp fonksiyonunun ekokardiyografik değerlendirmesi

Echocardiographic evaluation of systolic and diastolic heart function in patients suffering from beta-thalassemia major aged 5-10 years at the Zahedan Research Center for Children and Adolescent Health

Noor MOHAMMAD
Semira MEHRALIZADEH
Pages
150–153
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: The left ventricular mean IRT in the patient group was 114±21 and in the control group 94±10 msec (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Cardiac complications are the major cause of morbidity and mortality in beta-thalassemia major.
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Key Findings & Data:The aim of the study was to evaluate right (RV) and left (LV) ventricular systolic and diastolic functions using myocardial performance index in young, asymptomatic children suffering from thalassemia major, for early detection of cardiac function impairment, preventing further cardiac damage by modifying disease progression and treatment.
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Conclusion & Impact:Results: The left ventricular mean IRT in the patient group was 114±21 and in the control group 94±10 msec (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Cardiac complications are the major cause of morbidity and mortality in beta-thalassemia major. The aim of the study was to evaluate right (RV) and left (LV) ventricular systolic and diastolic functions using myocardial performance index in young, asymptomatic children suffering from thalassemia major, for early detection of cardiac function impairment, preventing further cardiac damage by modifying disease progression and treatment. Methods: A case-controlled, cross-sectional study involving 80 patients suffering from beta- thalassemia major and 80 children adjusted in terms of age and sex served as a control group were studied in Research Center for Children and Adolescent Health Zahedan. The relevant echocardiographic parameters were measured in both subject groups: myocardial performance index (MPI), isovolumic relaxation time (IRT), isovolumic contraction time (ICT), pre-ejection period (PEP), ejection time (ET), PEP/ET ratio, deceleration time (DT) and acceleration time (AT). Data were analyzed by unpaired Student t test. Results: The left ventricular mean IRT in the patient group was 114±21 and in the control group 94±10 msec (p

Özet

Amaç: Çalışmanın amacı, kalp fonksiyon bozukluğunu erkenden teşhis ederek, daha sonraki kalp hasarını önlemek için hastalığın seyrinde ve tedavisinde gerekli değişiklikleri yapmada talasemi majörlü genç ve asemptomatik çocuklarda miyokart indeksini kullanarak sağ ve sol ventrikülün sistolik ve diyastolik fonksiyonlarını değerlendirmekti. Yöntemler: Zahedan Çocuk ve Genç Sağlığı Araştırma Merkezinde yaş ve cinse göre uyumlu, 80 sağlıklı çocuk ve beta-talasemi majörlü 80 hastanın dahil olduğu olgu-kontrollü, enine-kesitsel bir çalışma yapıldı. Her iki grupta da ilgili ekokardiyografik parametreler ölçüldü: Miyokart performans indeksi (MPI), izovolümik relaksasyon zamanı (IRT), izovolümik kasılma zamanı (ICT), pre-ejeksiyon dönemi, PEP/ET oranı, deselerasyon zamanı (DT) ve akselerasyon zamanı (AT). Veriler eşleştirilmemiş Student t testi ile analiz edildi. Bulgular: Sol ventrikül ortalama IRT hasta grubunda 114±21 ve kontrol grubunda 94±10 msn (p

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Cite This Article

MOHAMMAD, N., MEHRALIZADEH, S. (2022). Zahedan Çocuk ve Genç Sağlığı Araştırma Merkezindeki 5-10 yaşlarındaki beta-talasemi majörü olan hastalarda sistolik ve diyastolik kalp fonksiyonunun ekokardiyografik değerlendirmesi. Anadolu Kardiyoloji Dergisi, Cilt: 10 - Sayı: 2, 150–153. https://ajindex.com/articles/436789

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