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Journals / Anadolu Kardiyoloji Dergisi / 2011 / Cilt: 11 - Sayı: 3

Koroner arter hastalığı ve tokluk trigliserid düzeyleri arasında herhangi bir ilişki var mıdır?

Is there any relationship between coronary artery disease and postprandial triglyceride levels?

İnci Aslı ATAR
Haldun MÜDERİSOĞLU
Aylin YILDIRIR
Bülent ÖZİN
İlyas ATAR
Alp AYDINALP
Çağatay ERTAN
Hüseyin BOZBAŞ
Pages
201–206
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Triglyceride levels were significantly increased after lipid-rich-breakfast loading compared to baseline levels in both groups (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We aimed to evaluate the relationship between postprandial triglyceride (PPTG) levels and coronary artery disease (CAD).Methods: A total of 80 patients were included in this prospective cohort study.
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Key Findings & Data:In the fasting state and after the high fat breakfast, triglyceride levels were measured by enzymatic methods at 2nd, 4th, 6th and 8th hours.
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Conclusion & Impact:Triglyceride levels were significantly increased after lipid-rich-breakfast loading compared to baseline levels in both groups (p
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to evaluate the relationship between postprandial triglyceride (PPTG) levels and coronary artery disease (CAD).Methods: A total of 80 patients were included in this prospective cohort study. Oral lipid loading was used in order to measure PPTG levels. In the fasting state and after the high fat breakfast, triglyceride levels were measured by enzymatic methods at 2nd, 4th, 6th and 8th hours. We made subgroup analysis to show the effects of lipid loading on triglyceride levels in patients with and without fasting hypertriglyceridemia. We evaluated triglyceride levels and changes of triglyceride levels in percentages after lipid loading using a general linear model for repeated measures. Sample size analysis was performed. Results: Baseline clinical, demographic and laboratory characteristics of both groups were similar. The peak triglyceride levels were seen at the 4th hour in both groups. Triglyceride levels were significantly increased after lipid-rich-breakfast loading compared to baseline levels in both groups (p

Özet

Amaç: Biz bu çalışmada, tokluk trigliserid (TTG) düzeyi ve koroner arter hastalığı (KAH) arasındaki ilişkiyi araştırmayı amaçladık.Yöntemler: Bu prospektif kohort çalışmasına toplam 80 hasta dahil edildi ve TTG düzeyini ölçmek için ağızdan lipit yüklemesi yapıldı. Aç olarak ve lipitten zengin bir kahvaltı sonrası 2., 4., 6. ve 8. saatte tok olarak trigliserid düzeyi enzimatik yöntemle ölçüldü. Açlık trigliserid yüksekliği olan ve olmayan bireylerde lipit yüklemesinin trigliserid düzeyi üzerine etkisinin değerlendirilmesi için alt grup analizi uygulandı. Lipid yüklemesi sonrası trigliserid düzeyleri ve trigliserid düzeyindeki yüzde değişim oranları “tekrarlayan değerler için genel lineer model” analizi ile değerlendirildi. Örneklem büyüklüğü hesaplandı. Bulgular: Başlangıçtaki klinik, demografik ve biyokimyasal ölçümlerin sonuçları gruplar arasında benzerdi. Her iki grupta da zirve trigliserid seviyesi lipit yüklemesi sonrası 4. saatteydi. Lipit yüklemesi sonrası her iki grupta da trigliserid düzeyleri başlangıca göre anlamlı olarak arttı (p

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Cite This Article

ATAR, İ. A., MÜDERİSOĞLU, H., YILDIRIR, A., ÖZİN, B., ATAR, İ., AYDINALP, A., ERTAN, Ç., BOZBAŞ, H. (2022). Koroner arter hastalığı ve tokluk trigliserid düzeyleri arasında herhangi bir ilişki var mıdır?. Anadolu Kardiyoloji Dergisi, Cilt: 11 - Sayı: 3, 201–206. https://ajindex.com/articles/436765

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