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Journals / Anadolu Kardiyoloji Dergisi / 2010 / Cilt: 10 - Sayı: 4

Farklı atriyal fibrilasyon türlerinde plazma renin aktivitesi ve pro-B-tipi natriüretik peptit düzeyleri

Plasma renin activity and pro-B-type natriuretic peptide levels in different atrial fibrillation types

Gürkan ACAR
Ömer GEDİKLİ
Mehmet ÖZAYDIN
Abdullah DOĞAN
Pages
317–322
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: Median NT-proBNP levels were higher in overall patients with AF than in controls [114 (63-165) vs 50 (38-58) pg/ml, p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Renin-angiotensin system may be activated during atrial fibrillation (AF).
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Key Findings & Data:Methods: This cross-sectional study included 97 patients with recent (≤7 days), persistent (7 days to 12 months) and permanent AF (>12 months), and age- and sex-matched 30 controls with sinus rhythm.
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Conclusion & Impact:Results: Median NT-proBNP levels were higher in overall patients with AF than in controls [114 (63-165) vs 50 (38-58) pg/ml, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Renin-angiotensin system may be activated during atrial fibrillation (AF). Our aim was to evaluate plasma renin activity (PRA) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in patients with different AF types who had normal left ventricular (LV) systolic function. Methods: This cross-sectional study included 97 patients with recent (≤7 days), persistent (7 days to 12 months) and permanent AF (>12 months), and age- and sex-matched 30 controls with sinus rhythm. Plasma levels of PRA and NT-pro-BNP were measured and presented as median (25th-75th percentiles). Echocardiographic examination was performed in all population. Variance and logistic regression analyses were also used for multiple comparisons and independent predictors, respectively. Results: Median NT-proBNP levels were higher in overall patients with AF than in controls [114 (63-165) vs 50 (38-58) pg/ml, p

Özet

Atriyal fibrilasyon (AF) sırasında renin-anjiyotensin sistemi (RAS) aktif olabilir. Amacımız, sol ventrikül sistolik fonksiyonu normal olan farklı AF hastalarında, plazma renin aktivitesi (PRA) ve N-terminal pro-B-tipi natriüretik peptit (NT-proBNP) düzeylerini değerlendirmektir. Yöntemler: Bu kesitsel çalışmaya, yeni (≤7 gün), persistan (7 gün ile 12 ay) ve kalıcı AF’si (>12 ay) olan 97 hasta alındı. Yaş ve cinsiyeti benzer sinüs ritimli 30 sağlıklı birey kontrol grubunu oluşturdu. Plazma PRA ve NT-pro-BNP düzeyleri ölçüldü (mediyan, 25th - 75th persantil). Tüm popülasyona ekokardiyografi yapıldı. Standart testlere ek olarak, çoklu karşılaştırmalar için varyans analizi ve bağımsız prediktörler için lojistik regresyon analizi kullanıldı. Bulgular: Tüm AF grubunun ortanca NT-proBNP düzeyi, kontrol grubundan daha yüksekti [114 (63-165)’e 50 (38-58) pg/ml, p

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Cite This Article

ACAR, G., GEDİKLİ, Ö., ÖZAYDIN, M., DOĞAN, A. (2022). Farklı atriyal fibrilasyon türlerinde plazma renin aktivitesi ve pro-B-tipi natriüretik peptit düzeyleri. Anadolu Kardiyoloji Dergisi, Cilt: 10 - Sayı: 4, 317–322. https://ajindex.com/articles/436752

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