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Journals / Anadolu Kardiyoloji Dergisi / 2011 / Cilt: 11 - Sayı: 5

Evaluation of the relationship between serum high sensitive C-reactive protein and the elasticity properties of the aorta in patients with coronary artery ectasia

Koroner ektazisi olan hastalarda aortun elastik özellikleri ile serum yüksek duyarlılıklı C-reaktif protein arasındaki ilişkinin değerlendirilmesi

Necip ERMİŞ
Nusret AÇIKGÖZ
Erdal AKTÜRK
İsa SİNCER
Mustafa KOŞAR FERİDUN
Pages
414–420
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Serum levels of hsCRP in CAE group were higher than in the controls (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Previous studies have shown an association between high sensitive C-reactive protein (hsCRP) and arterial stiffness in most cardiovascular diseases.
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Key Findings & Data:Serum hsCRP levels and aortic stiffness parameters were measured in CAE patients (n=28) and age - and gender-matched control subjects (n=25).
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Conclusion & Impact:Results: Serum levels of hsCRP in CAE group were higher than in the controls (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Previous studies have shown an association between high sensitive C-reactive protein (hsCRP) and arterial stiffness in most cardiovascular diseases. High sensitive C-reactive protein and arterial stiffness have been considered as independent predictors of cardiovascular mortality in cardiovascular disease. The aim of this study was to investigate the relationship between hsCRP, a marker of systemic inflammation and aortic stiffness in patients with coronary artery ectasia (CAE). Methods: Our study was designed as cross-sectional study. Serum hsCRP levels and aortic stiffness parameters were measured in CAE patients (n=28) and age - and gender-matched control subjects (n=25). Serum hsCRP levels were determined by an immunonephelometry assay. Aortic strain (AS) and aortic distensibility (AD) were calculated from the aortic diameters measured using M-mode echocardiography and blood pressure obtained by sphygmomanometry. Independent samples “t” test, Chi-square test and Spearman correlation test were used for statistical analysis. Results: Serum levels of hsCRP in CAE group were higher than in the controls (p

Özet

Amaç: Daha önceki çalışmalar, kardiyovasküler hastalıklar ile arteryel sertlik ve yüksek duyarlı C-reaktif protein (hsCRP) arasındaki ilişkiyi göstermektedir. Serum hsCRP ve arteryel sertlik, kardiyovasküler hastalıklara bağlı mortalitenin bağımsız prediktörleri olarak düşünülmektedir. Çalışmamızın amacı koroner ektazisi (KAE) olan hastalarda aortik sertlik ile enflamatuvar marker olan hsCRP arasındaki ilişkiyi araştırmaktı. Yöntemler: Çalışmamız enine kesitsel olarak dizayn edildi. Serum hsCRP seviyeleri ve aortik sertlik parametreleri, aynı yaş ve cinsiyette olan 28 koroner ektazili hasta ve 25 kontrol grubunda karşılaştırıldı. Serum hsCRP seviyeleri, immünonefelometrik analiz yöntemiyle ölçüldü. Aortik gerilim (AG) ve aortik distensibilite (AD) sfigmomanometre ile ölçülen kan basınçları ve M-mod ekokardiyografi kullanılarak ölçülen aortik çaplardan hesaplandı.İstatistiksel analizde bağımsız örneklem t-testi, Ki-kare testi ve Spearman korelasyon testi kullanıldı. Bulgular: Koroner arter ektazisi (KAE) grubunda serum hsCRP seviyeleri kontrol grubundan daha yüksekti (p

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Cite This Article

ERMİŞ, N., AÇIKGÖZ, N., AKTÜRK, E., SİNCER, İ., FERİDUN, M. K. (2022). Evaluation of the relationship between serum high sensitive C-reactive protein and the elasticity properties of the aorta in patients with coronary artery ectasia. Anadolu Kardiyoloji Dergisi, Cilt: 11 - Sayı: 5, 414–420. https://ajindex.com/articles/436665

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