Journals / Anadolu Kardiyoloji Dergisi / 2011 / Cilt: 11 - Sayı: 2

Sirkadiyen kan basıncı paterni ve kardiyak otonomik işlevler: Aynı patofizyolojinin farklı yönleri

Circadian blood pressure pattern and cardiac autonomic functions: different aspects of same pathophysiology

Pages
168–173
Publication Date
2022-10-10
DOI
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⚡ TL;DR(Too Long; Didn't Read)

In this paper, we aimed to review the studies evaluating the relationship between circadian arterial blood pressure pattern and indices of cardiac autonomic functions.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Arterial blood pressure fluctuates with a pattern that follows a circadian rhythm, with a peak in the early morning hours and a trough during nighttime.
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Key Findings & Data:Nocturnal dipping of arterial blood pressure is part of this normal circadian pattern, and its absence, which is called non-dipping is associated with more severe end-organ damage and increased risk of cardiovascular events, especially in hypertensive patients.
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Conclusion & Impact:In this paper, we aimed to review the studies evaluating the relationship between circadian arterial blood pressure pattern and indices of cardiac autonomic functions.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Arterial blood pressure fluctuates with a pattern that follows a circadian rhythm, with a peak in the early morning hours and a trough during nighttime. Nocturnal dipping of arterial blood pressure is part of this normal circadian pattern, and its absence, which is called non-dipping is associated with more severe end-organ damage and increased risk of cardiovascular events, especially in hypertensive patients. Although pathologic mechanisms are still unclear, it has been suggested that non-dippers show impairment in the autonomic system functions that include abnormal parasympathetic and sympathetic activities. Several studies have examined the role of the autonomic nervous system in the non-dipping phenomenon. In this paper, we aimed to review the studies evaluating the relationship between circadian arterial blood pressure pattern and indices of cardiac autonomic functions.

Özet

rteriyel kan basıncı sabahın erken saatlerinde zirveye, gece saatlerinde en düşük değerlere ulaşan sirkadiyen bir ritim paterni izlemektedir. Geceleri arteriyel kan basıncındaki düşüş normal sirkadiyen paternin bir parçasıdır. Bu düşüşün görülmediği “non-dipping” olarak adlandırılan sirkadiyen kan basıncı paterni, özellikle hipertansif hastalarda, daha şiddetli hedef organ hasarı ve artmış kardiyovasküler olaylarla birliktedir. Her ne kadar altta yatan mekanizmalar tam olarak bilinmese de “non-dipping” paterni olan kişilerde anormal parasempatik ve sempatik aktiviteleri içeren otonom sistem bozukluğunun olduğu öne sürülmüştür. “Non-dipping” fenomeninde otonom sinir sisteminin rolü birçok çalışmada incelenmiştir. Bu yazıda, sirkadiyen arteriyel kan basıncı paterni ile kardiyak otonomik işlevlerin göstergeleri arasındaki ilişkiyi değerlendiren çalışmaları derlemeyi amaçladık.

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Cite This Article

KARAKULAK, U. N., KABAKÇI, G., OKUTUCU, S. (2022). Sirkadiyen kan basıncı paterni ve kardiyak otonomik işlevler: Aynı patofizyolojinin farklı yönleri. Anadolu Kardiyoloji Dergisi, Cilt: 11 - Sayı: 2, 168–173. https://ajindex.com/articles/436519

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References (15)

  1. Biaggioni I. Circadian clocks, autonomic rhythms and blood pressure dipping. Hypertension 2008; 52: 797-8
  2. Fukutomi M, Matsui Y, Shimada K. [Dipper and non-dipper]. Nippon Rinsho 2006; 64 Suppl 6:33-8
  3. Izzedine H, Launay-Vacher V, Deray G. Abnormal blood pressure circadian rhythm: a target organ damage? Int J Cardiol 2006; 107: 343-9
  4. Pierdomenico SD, Lapenna D, Guglielmi MD, Costantini F, Romano F, Schiavone C, et al. Arterial disease in dipper and nondipper hypertensive patients. Am J Hypertens 1997; 10: 511-8
  5. Kohno I, Takusagawa M, Yin D, Okutani M, Mochizuki Y, Sano S, et al. QT dispersion in dipper- and nondipper-type hypertension. Am J Hypertens 1998; 11: 280-5
  6. Shimada K, Kario K. Altered circadian rhythm of blood pressure and cerebrovascular damage. Blood Press Monit 1997; 2: 333-8
  7. Zweiker R, Eber B, Schumacher M, Toplak H, Klein W. "Nondipping" related to cardiovascular events in essential hypertensive patients. Acta Med Austriaca 1994; 21: 86-9
  8. Nakano Y, Oshima T, Ozono R, Higashi Y, Sasaki S, Matsumoto T, et al. Non-dipper phenomenon in essential hypertension is related to blunted nocturnal rise and fall of sympatho-vagal nervous activity and progress in retinopathy. Auton Neurosci 2001; 88: 181-6
  9. Shaw E, Tofler GH. Circadian rhythm and cardiovascular disease. Curr Atheroscler Rep 2009; 11: 289-95
  10. Maemura K, Takeda N, Nagai R. Circadian rhythms in the CNS and peripheral clock disorders: role of the biological clock in cardiovascular diseases. J Pharmacol Sci 2007; 103: 134-8
  11. Henskens LH, Kroon AA, van Oostenbrugge RJ, Haest RJ, Lodder J, de Leeuw PW. Different classifications of nocturnal blood pressure dipping affect the prevalence of dippers and nondippers and the relation with target-organ damage. J Hypertens 2008; 26: 691-8
  12. Shimada K, Kawamoto A, Matsubayashi K, Nishinaga M, Kimura S, Ozawa T. Diurnal blood pressure variations and silent cerebrovascular damage in elderly patients with hypertension. J Hypertens 1992; 10: 875-8
  13. Ohkubo T, Hozawa A, Yamaguchi J, Kikuya M, Ohmori K, Michimata M, et al. Prognostic significance of the nocturnal decline in blood pressure in individuals with and without high 24-h blood pressure: the Ohasama study. J Hypertens 2002; 20: 2183-9
  14. White WB. Ambulatory blood pressure as a predictor of target organ disease and outcome in the hypertensive patient Blood Press Monit 1999; 4: 181-4
  15. Spallone V, Maiello MR, Cicconetti E, Pannone A, Barini A, Gambardella