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Journals / Anadolu Kardiyoloji Dergisi / 2012 / Cilt: 12 - Sayı: 1

Premenapozal şişman kadınlarda P dalga dispersiyonu karotis intima-media kalınlığı ve C-reaktif protein arasındaki ilişki; Gözlemsel bir çalışma

Association between C-reactive protein, carotid intima-media thickness and P-wave dispersion in obese premenopausal women: An observational study

Gülhan AKBABA
Dilek BERKER
Ferhat GÖKAY
Serhat IŞIK
Yasemin TÜTÜNCÜ
Ufuk ÖZUĞUZ
Gökhan ERGÜN
Serdar GÜLER
Pages
40–46
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: The obese group had significantly higher values for PWD (41.8±11.8 ms vs. 28.5±9.3 ms; p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of the present study was to evaluate P-wave dispersion (PWD) in obese women, and to investigate the relationship between P-wave measurements, high sensitive C-reactive protein (hsCRP), carotid intima-media thickness (CIMT) and echocardiographic findings.
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Key Findings & Data:Methods: Forty-four patients with obese premenopausal women and 30 females with normal weight were enrolled this cross sectional, observational study.
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Conclusion & Impact:Results: The obese group had significantly higher values for PWD (41.8±11.8 ms vs. 28.5±9.3 ms; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of the present study was to evaluate P-wave dispersion (PWD) in obese women, and to investigate the relationship between P-wave measurements, high sensitive C-reactive protein (hsCRP), carotid intima-media thickness (CIMT) and echocardiographic findings. Methods: Forty-four patients with obese premenopausal women and 30 females with normal weight were enrolled this cross sectional, observational study. Results of anthropometric measurements, laboratory assays, electrocardiographic and echocardiographic findings were recorded for each participant. Student t, Mann-Whitney U and Pearson Chi-square tests, and Spearman correlation analysis were used for statistical analysis. Multiple regression analysis was used to identify independent factors associated with PWD development. Results: The obese group had significantly higher values for PWD (41.8±11.8 ms vs. 28.5±9.3 ms; p

Özet

Amaç: Çalışmamızın amacı, premenapozal obez kadınlarda P dalga dispersiyonunun incelenmesi, P dalga ölçümleri ile yüksek duyarlılıklı C-reaktif protein (hsCRP), karotis intima-media kalınlığı (KIMK) ve ekokardiyografi bulguları arasındaki ilişkilerin değerlendirilmesidir. Yöntemler: Kırk dört premenapozal obez kadın ve 30 normal kilolu, sağlıklı, gönüllü, kesitsel gözlemsel çalışmaya dahil edildi. Tüm katılımcılarda, antropometrik ölçümlerden sonra açlık kan şekeri, insülin düzeyi, insülin direnci (HOMA-IR), hsCRP, lipit parametreleri ve KIMK ölçüldü, elektrokardiyografik ve ekokardiyografik parametreler değerlendirildi. İstatistiksel analizde Student t, Mann-Whitney U ve Pearson Ki-kare testleri, ve Spearman korelasyonu analizi kullanıldı. Çoklu doğrusal regresyon analizi ile P dalga dispersiyonu gelişimini etkileyen bağımsız belirleyicileri araştırıldı. Bulgular: Premenapozal obez kadınlar ile sağlıklı kontrol grubu arasında P dispersiyonu ve maksimum P dalga süresi açısından anlamlı farklılık vardı (sırasıyla, 41.8±11.8 ms’ye karşı 28.5±9.3 ms, p

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Cite This Article

AKBABA, G., BERKER, D., GÖKAY, F., IŞIK, S., TÜTÜNCÜ, Y., ÖZUĞUZ, U., ERGÜN, G., GÜLER, S. (2022). Premenapozal şişman kadınlarda P dalga dispersiyonu karotis intima-media kalınlığı ve C-reaktif protein arasındaki ilişki; Gözlemsel bir çalışma. Anadolu Kardiyoloji Dergisi, Cilt: 12 - Sayı: 1, 40–46. https://ajindex.com/articles/436474

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