Journals / Anadolu Kardiyoloji Dergisi / 2012 / Cilt: 12 - Sayı: 2

Evaluation of clinical and demographic characteristics and their association with length of hospital stay in patients admitted to cardiac intensive care unit with the diagnosis of acute heart failure

Akut kalp yetersizliği nedeni ile kardiyoloji yoğun bakım ünitesine yatırılan hastaların klinik ve demografik özelliklerinin ve bu özelliklerin hastanede kalış süresi ile ilişkisinin incelenmesi

Pages
123–131
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, in-hospital mortality was high and initial clinical presentation characteristics were significantly associated with in-hospital outcome.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Despite increasing incidence, data regarding clinical and demographic characteristics of patients with acute heart failure (AHF) admitted to cardiac intensive care unit (ICU) are inconclusive.
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Key Findings & Data:Methods: We conducted a single-center, prospective study involving 150 patients hospitalized to cardiac ICU with the primary diagnosis of AHF.
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Conclusion & Impact:However, in-hospital mortality was high and initial clinical presentation characteristics were significantly associated with in-hospital outcome.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Despite increasing incidence, data regarding clinical and demographic characteristics of patients with acute heart failure (AHF) admitted to cardiac intensive care unit (ICU) are inconclusive. The aim of this study was to assess the presentation characteristics and factors determining the length of hospital stay in this particular patient population. Methods: We conducted a single-center, prospective study involving 150 patients hospitalized to cardiac ICU with the primary diagnosis of AHF. Chi-square and Student t tests were used for the analysis of categorical and continuous variables, respectively. Linear regression analysis (LRA) was used to determine the factors affecting the length of hospital stay. Results: Forty-nine percent of the patients had new-onset AHF and 25% had preserved left ventricular ejection fraction (LVEF). In 25.3% of all patients and 46.6% of the patients with new-onset HF the precipitating factor was acute coronary syndrome. Atrial fibrillation and valvular heart disease as precipitating factors were more common in patients with preserved EF, when compared to low EF group. LRA showed that presence of anemia [β=1.62; 95% CI 0.08-3.15; p=0.039)] and severe mitral regurgitation (β=2.55; 95% CI 0.06-5.05; p=0.045) and systolic blood pressure (β=-0.03; 95% CI -0.06 - -0.002; p=0.039) and blood urea nitrogen (β=0.034; 95% CI 0.006 - 0.06; p=0.016) were the independent predictors of length of stay. Conclusion: Underlying cardiovascular risk factors, comorbidities and precipitating pathologies were diverse and highlighted the inhomoge- neous characteristics of AHF syndromes. However, in-hospital mortality was high and initial clinical presentation characteristics were significantly associated with in-hospital outcome.

Özet

Amaç: Görülme sıklığındaki artışa rağmen, akut kalp yetersizliği (KY) nedeniyle kardiyoloji yoğun bakım ünitesine (YBÜ) kabul edilen hastaların klinik ve demografik özellikleri ile ilgili veriler yetersizdir. Çalışmamızın amacı, bu hasta grubundaki başvuru özelliklerinin ve hastanede kalış süresini etkileyen faktörlerin incelenmesidir. Yöntemler: Birincil akut KY tanısıyla kardiyoloji YBÜ’ne yatırılan 150 hastanın dahil edildiği tek-merkezli, ileriye dönük bir çalışma düzenlendi. Kategorik ve sürekli değişkenlerin analizi için sırasıyla Ki-kare ve Student-t testleri kullanıldı. Hastanede kalış süresini etkileyen bağımsız faktörleri belirlemek için lineer regresyon analizi kullanıldı. Bulgular: Hastaların %49’unda yeni başlangıçlı KY ve %25’inde korunmuş sol ventrikül ejeksiyon fraksiyonu (EF) tespit edildi. Hastaların %25.3’ünde, yeni başlangıçlı KY hastalarının ise %46.6’sında tetikleyici faktör akut koroner sendromdu. Korunmuş EF’li hastalarda tetikleyici faktör olarak atriyal fibrilasyon ve kalp kapak hastalıklarına düşük EF’li hastalara göre daha fazla oranda rastlandı. Lineer regresyon analizi, anemi (β=1.62; %95 GA 0.08-3.15; p=0.039) ve ciddi mitral yetersizliği (β=2.55; %95 GA 0.06-5.05; p=0.045) ile sistolik kan basıncı (β=-0.03; %95 GA -0.06 -0.002; p=0.039) ve kan üre azotunun (β=0.034; %95 GA 0.006-0.06; p=0.016) hastanede kalış süresinin bağımsız belirleyicileri olduğunu gösterdi. Sonuç: Altta yatan kardiyovasküler risk faktörlerinin, eşlik eden hastalıkların ve tetikleyici patolojilerin çeşitliliği AKY sendromlarının heterojen yapısını ortaya koymaktadır. Bununla birlikte, hastane içi ölüm oranları yüksektir ve başvuru sırasındaki klinik özellikler hastane içi seyir ile önemli bir ilişki gösterir.

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Cite This Article

DOĞAN, U., GÖK, H., ÖZDEMİR, K., ŞAHİN, S. (2022). Evaluation of clinical and demographic characteristics and their association with length of hospital stay in patients admitted to cardiac intensive care unit with the diagnosis of acute heart failure. Anadolu Kardiyoloji Dergisi, Cilt: 12 - Sayı: 2, 123–131. https://ajindex.com/articles/436437

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