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Journals / Anadolu Kardiyoloji Dergisi / 2012 / Cilt: 12 - Sayı: 7

Obstrüktif uyku apnesi olan hastalarda bir gecelik nazal sürekli pozitif hava yolu basıncı tedavisinin endotel fonksiyonuna etkisi

Effect of overnight nasal continuous positive airway pressure treatment on the endothelial function in patients with obstructive sleep apnea

Mehmet Tolga DOĞRU
Mehmet Savaş EKİCİ
Üçler KISA
Vedat ŞİMŞEK
Haksun EBİNÇ
Nesligül YILDIRIM
Murat TULMAÇ
Emine TİRELİ
Pages
560–565
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: With CPAP therapy apnea hypopnea indices were reduced (60.6±24.9/h vs. 9.6±7.9/h; p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this prospective study, we aimed to investigate acute effect of nasal continuous positive airway pressure (CPAP) therapy on the endothelial function of patients with obstructive sleep apnea syndrome (OSA) by using brachial artery flow mediated dilatation (FMD) method.
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Key Findings & Data:Methods: Newly diagnosed thirty OSA patients with ages between 29 and 72 years were included in this study.
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Conclusion & Impact:Results: With CPAP therapy apnea hypopnea indices were reduced (60.6±24.9/h vs. 9.6±7.9/h; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this prospective study, we aimed to investigate acute effect of nasal continuous positive airway pressure (CPAP) therapy on the endothelial function of patients with obstructive sleep apnea syndrome (OSA) by using brachial artery flow mediated dilatation (FMD) method. Methods: Newly diagnosed thirty OSA patients with ages between 29 and 72 years were included in this study. FMD and high sensitivity C-reactive protein (hsCRP) values of patients obtained before and after CPAP dose titration test were compared with paired samples t test or Wilcoxon signed ranks test. Results: With CPAP therapy apnea hypopnea indices were reduced (60.6±24.9/h vs. 9.6±7.9/h; p

Özet

Amaç: Bu prospektif çalışmamızda obstrüktif uyku apneli (OUA) hastalarda endotel fonksiyonuna nazal sürekli pozitif hava yolu basıncı (SPHB) tedavisinin akut etkisini brakiyal arterde akıma bağlı genişleme (ABG) yöntemini kullanarak değerlendirmeyi amaçladık. Yöntemler: Yeni tanı almış 29 ve 72 yaş arasında otuz OUA hastası çalışmaya dahil edildi. Hastaların SPHB doz titrasyonu öncesi ve sonrasında bakılan ABG ve yüksek duyarlıklı C-reaktif protein (ydCRP) değerleri eşleştirilmiş örneklem t-testi ya da Wilcoxon işaret rank testi ile karşılaştırıldı. Bulgular: SPHB tedavisi ile apne hipopne indeksleri azaldı (60.6±24.9/st vs. 9.6±7.9/st; p

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Cite This Article

DOĞRU, M. T., EKİCİ, M. S., KISA, Ü., ŞİMŞEK, V., EBİNÇ, H., YILDIRIM, N., TULMAÇ, M., TİRELİ, E. (2022). Obstrüktif uyku apnesi olan hastalarda bir gecelik nazal sürekli pozitif hava yolu basıncı tedavisinin endotel fonksiyonuna etkisi. Anadolu Kardiyoloji Dergisi, Cilt: 12 - Sayı: 7, 560–565. https://ajindex.com/articles/436386

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