Journals / Anadolu Kardiyoloji Dergisi / 2012 / Cilt: 12 - Sayı: 1

Tip 1 diyabetli hastalarda hipertansiyon-vücut yapısı ve vücut kitle indeksinin etkisi: Gözlemsel bir çalışma

Hypertension in type 1 diabetic patients-the influence of body composition and body mass index: An observational study

Pages
60–64
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Abdominal fat is the only factor related to mean arterial blood pressure and systolic blood pressure. (Anadolu Kardiyol Derg 2012; 12: 60-4)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To estimate the influence of body composition and body mass index on blood pressure in type 1 diabetic patients.
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Key Findings & Data:Methods: This cross-sectional, observational study included 45 type 1 diabetic patients and 30 age and sex matched healthy volunteers.
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Conclusion & Impact:Abdominal fat is the only factor related to mean arterial blood pressure and systolic blood pressure. (Anadolu Kardiyol Derg 2012; 12: 60-4)
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: To estimate the influence of body composition and body mass index on blood pressure in type 1 diabetic patients. Methods: This cross-sectional, observational study included 45 type 1 diabetic patients and 30 age and sex matched healthy volunteers. Blood pressure, anthropometric measurements, and body composition by dual X-ray absorptiometry (DXA) were done for all patients and controls. T-test, one way ANOVA and multiple regressions were used for statistical analyses. Results: Twenty diabetic patients (44.4%) had hypertension. Hypertensive diabetic patients had the highest total fat mass %, soft tissue fat mass %, abdomen fat % and fat/lean ratio followed by non hypertensives and the least was the controls (p=0.0001). Abdominal fat % was the only parameter significantly associated with mean arterial blood pressure (β-5.8, 95% CI: 3.7-8.0, p=0.0001) and systolic blood pressure (β-8.6, 95% CI: 5.4-11.9, p=0.0001) by stepwise multiple regression analysis in the diabetic patients. In the contrary, abdominal fat % (β-2.7, 95% CI: 0.9-4.5, p=0.006), duration of diabetes (β-2.5, 95% CI: 1.4-3.5, p=0.0001) and fat/ lean ratio (β-11.7, 95% CI: 1.5-21.9, p=0.03) were related to diastolic blood pressure. Conclusion: Diabetes is associated with an increase in body fat especially abdominal, which leads to an increase in insulin resistance and decrease in lean mass. In type 1 diabetic patients, blood pressure depends on body mass index SDS and fat mass. Abdominal fat is the only factor related to mean arterial blood pressure and systolic blood pressure. (Anadolu Kardiyol Derg 2012; 12: 60-4)

Özet

Amaç: Tip 1 diyabetli hastalarda kan basıncına vücut yapısının ve kitle indeksinin etkisini tahmin etmektir. Yöntemler: Bu kesitsel gözlemsel çalışmaya Tip 1 diyabetli 45 hasta, sağlıklı yaş ve cinsiyeti eşleştirilmiş, 30 gönüllü dahil edildi. Bütün hastalar ve kontroller için kan basıncı antropometrik ölçümler ve vücut bileşimi için de çift X-ray absorbsiyometri (DXA) yapıldı. İstatistiksel analiz için t-testi, tek yön ANOVA ve çoklu regresyon analizleri kullanıldı. Bulgular: Yirmi diyabetli hastanın (%44.4) hipertansiyonu vardı. Hipertansif diyabetik hastalarda önemli derecede daha yüksek toplam yağ kitlesi yüzdesi, yumuşak doku yağ kütle yüzdesi, karın yağı yüzdeleri, yağlı/yağsız oranını hipertansif olmayanlar izledi, en azı da kontrollerde idi (p=0.0001). Diyabetli hastalarda çoklu regresyon analizi, abdominal yağ yüzdesinin, ortalama arteryel kan basıncı (β-5.8, %95 GA: 3.7-8.0, p=0.0001) ve sistolik kan basıncı (β-8.6, 95% GA: 5.4-11.9, p=0.0001) ile ilişkili tek parametre olduğunu gösterdi. Aksine, abdominal yağ oranı yüzdesi (β-2.7, %95 GA: 0.9-4.5, p=0.006), diyabetin süresi (β-2.5, %95 GA: 1.4-3.5, p=0.0001), yağlı/yağsız oranı (β-11.7, %95 GA: 1.5-21.9, p=0.03) diyastolik kan basıncı ile ilişkili idi. Sonuç: Diyabet özellikle vücutta abdominal yağda artışa yol açar. Bu da insülin direncinin artmasına ve yağsız kitlenin azalmasına neden olur. Tip 1 diyabetli hastalarda kan basıncı vücut kitle indeksi, standart sapma puanına ve yağ kütlesine bağlıdır. Abdominal yağ dokusu, ortalama arteryel ve sistolik kan basıncı ile ilgili tek faktördür. (Anadolu Kardiyol Derg 2012; 12: 60-4)

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Cite This Article

BATTAH, A. A., DAYEM, S. M. A. E. (2022). Tip 1 diyabetli hastalarda hipertansiyon-vücut yapısı ve vücut kitle indeksinin etkisi: Gözlemsel bir çalışma. Anadolu Kardiyoloji Dergisi, Cilt: 12 - Sayı: 1, 60–64. https://ajindex.com/articles/436376

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