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Journals / Anadolu Kardiyoloji Dergisi / 2013 / Cilt: 13 - Sayı: 8

Gilbert sendromlu hastalarda epikardiyal yağ doku kalınlığı ve adiponektin seviyesinin düşük kardiyak riskle birlikteliğinin değerlendirilmesi: Gözlemsel bir çalışma

The evaluation of relationship between adiponectin levels and epicardial adipose tissue thickness with low cardiac risk in Gilbert's syndrome: an observational study

Yüksel ÇİÇEK
Erkan CÜRE
Arif YILMAZ
Süleyman YÜCE
Aynur KIRBAŞ
Medine Cumhur CÜRE
Pages
791–796
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

When comparing the two groups, the EAT thickness of the GS group was found to be significantly lower (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Atherosclerotic heart diseases are less frequently seen in patients with Gilbert’s syndrome (GS).
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Key Findings & Data:Methods: Sixty-eight patients diagnosed with GS (39 females and 29 males) who had applied at the internal medicine clinic of the hospital were included in this cross-sectional, observational study.
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Conclusion & Impact:When comparing the two groups, the EAT thickness of the GS group was found to be significantly lower (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Atherosclerotic heart diseases are less frequently seen in patients with Gilbert’s syndrome (GS). We aimed to investigate whether serum adiponectin (APN) and epicardial adipose tissue (EAT) thickness have an effect beside the antioxidant effect of bilirubin in lowering the incidence of the atherosclerotic process. Methods: Sixty-eight patients diagnosed with GS (39 females and 29 males) who had applied at the internal medicine clinic of the hospital were included in this cross-sectional, observational study. The control group included 63 healthy people (39 females and 24 males). EAT thickness was measured by echocardiography. The serum APN levels were also checked. Statistical analysis was performed by using independent sample t-test, Pearson correlation and linear regression analyses. Results: The mean age of the GS group was 28±9 years, and the average EAT thickness was found to be 2.5±0.1 mm. The mean age of the con- trol group was 26±6 years, and the average EAT thickness was found to be 4.2±0.5 mm. When comparing the two groups, the EAT thickness of the GS group was found to be significantly lower (p

Özet

Amaç: Gilbert sendromlu (GS) hastalarda aterosklerotik kalp hastalıkları daha az sıklıkla görülmektedir. Bilirubinin antioksidan etkisi yanında serum adiponektin (APN) ve epikardiyal yağ doku (EYD) kalınlığının aterosklerotik sürecin az görülmesinde etkisi olup olmadığını araştırmayı amaçladık. Yöntemler: Hastanemiz iç hastalıkları polikliniğine başvuran toplam 68 GS hastası (39 kadın, 29 erkek) bu kesitsel gözlemsel çalışmaya dahil edildi. Kontrol grubuna 63 sağlıklı birey (39 kadın, 24 erkek) alındı. EYD kalınlığı ekokardiyografi ile ölçüldü. Serum APN seviyeleri de ölçüldü. İstatistiksel analizde bağımsız örneklem t-testi, Pearson korelasyon ve lineer regresyon analizi kullanıldı. Bulgular: GS hastalarda ortalama yaş 28±9 yıl ve ortalama EYD kalınlığı 2,5±0,1 mm bulundu. Kontrol grubunun yaş ortalaması 26±6 yıl ve orta- lama EYD kalınlığı 4,2±0,5 mm bulundu. İki grup karşılaştırıldığında GS grubunda EYD kalınlığı kontrol grubundan anlamlı düşük bulundu (p

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Cite This Article

ÇİÇEK, Y., CÜRE, E., YILMAZ, A., YÜCE, S., KIRBAŞ, A., CÜRE, M. C. (2022). Gilbert sendromlu hastalarda epikardiyal yağ doku kalınlığı ve adiponektin seviyesinin düşük kardiyak riskle birlikteliğinin değerlendirilmesi: Gözlemsel bir çalışma. Anadolu Kardiyoloji Dergisi, Cilt: 13 - Sayı: 8, 791–796. https://ajindex.com/articles/436290

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