Journals / Anadolu Kardiyoloji Dergisi / 2013 / Cilt: 13 - Sayı: 6

Yirmi-elli yaş arası sağlıklı erkeklerde geleneksel koroner risk faktörleri: Yüksek yoğunluklu lipoprotein kolesterol üzerine odaklanma

Traditional coronary risk factors in healthy Turkish military personnel between 20 and 50 years old: Focus on high-density lipoprotein cholesterol

Pages
552–558
Publication Date
2022-10-10
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This issue needs further clarification in specific age groups without sedentary lifestyle.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Previous studies presented the Turkish population as a typical example of nations with low levels of high-density lipoprotein choles- terol (HDL-c).
📊
Key Findings & Data:Methods: In this observational and cross-sectional study, the data of 820 male military personnel between 20-50 years old (mean age: 35.3±6.9) who applied to the hospital for routine health examination were included.
💡
Conclusion & Impact:This issue needs further clarification in specific age groups without sedentary lifestyle.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Previous studies presented the Turkish population as a typical example of nations with low levels of high-density lipoprotein choles- terol (HDL-c). Nevertheless, some recent studies opposed this suggestion. We aimed to examine the traditional cardiovascular risk factors in young-middle age male military professionals, focusing especially on HDL-c. Methods: In this observational and cross-sectional study, the data of 820 male military personnel between 20-50 years old (mean age: 35.3±6.9) who applied to the hospital for routine health examination were included. Blood biochemistry, arterial blood pressure and anthropometric measurements were noted. Statistical analysis was performed using Kruskal-Wallis test and ANCOVA. Results: The mean age was 35.3±6.9, body mass index was 25.8±3.4 kg/m2 and waist circumference was 93.1±8.7 cm. HDL-c, low-density cho- lesterol, triglyceride and fasting blood glucose levels were 47.6±11.3, 120.4±33.2, 150.4±86.4 and 96,6±13.0 mg/dL, respectively. Only 23.2% of the participants had HDL-c level less than 40 mg/dL. The ratio of current smokers was 40.7%. Almost 66% of the participants (n=545) were making regular exercise. Mean systolic and diastolic arterial blood pressures were 124.1±13.0 and 75.7±9.3 mm Hg, respectively. Conclusion: The “mean” levels of traditional coronary risk factors were in almost “normal” limits in healthy young-middle age male military professionals that were examined. It must be emphasized that the HDL-c level, which was defined as “genetically low in Turks” in some previ- ous epidemiologic studies, was not really low. This finding may be due to relatively favorable life style of the study population. On the other hand, some recent population studies in Turkey had found HDL-c levels higher than it was thought. This issue needs further clarification in specific age groups without sedentary lifestyle.

Özet

Amaç: Önceki çalışmalar Türk toplumunu, yüksek yoğunluklu lipoprotein kolesterolü (YYL-k) düşük seviyede seyreden toplumların tipik bir örne- ği olarak gösteriyordu. Ancak yeni bazı çalışmalar bu görüşün tersini desteklemektedir. Biz bu çalışmamızda genç-orta yaşlı profesyonel erkek askerlerde geleneksel kardiyovasküler risk faktörlerini, özellikle YYL-k düzeyleri üzerinde yoğunlaşarak araştırmayı hedefledik. Yöntemler: Rutin sağlık kontrolü için hastaneye başvuran 20-50 (ortalama yaş: 35,3±6,9) yaş arası 820 erkek askeri personel bu gözlemsel ve enine-kesitli çalışmaya dahil edildi. Kan biyokimyası, arteriyal kan basıncı ve antropometrik ölçümler kayıt edildi. İstatistiksel analiz Kruskal- Wallis testi ve ANCOVA ile yapıldı. Bulgular: İncelenen grupta ortalama yaş 35,3±6,9, vücut kitle indeksi 25,8±3,4 kg/m2 ve bel çevresi 93,1±8,7 cm idi. YYL -k, düşük yoğunluklu kolesterol, trigliserid ve açlık kan şekeri düzeyleri sırasıyla 47,6±11,3, 120,4±33,2, 150,4±86,4 ve 96,6±13,0 mg/dL idi. Çalışmaya katılanların sade- ce %23,2’nin YYL-k düzeyi 40 mg/dL’nin altında bulundu. Aktif sigara içenlerin oranı %40,7, düzenli egzersiz yapanların oranı %66 idi. Ortalama sistolik ve diyastolik kan basınçları sırasıyla 124,1±13,0 ve 75,7±9,3 mm Hg olarak bulundu. Sonuç: Çalışma grubunu oluşturan sağlıklı, genç/orta yaşlı, erkek, profesyonel askerlerde incelenen geleneksel kardiyovasküler risk faktörleri nor- mal sınırlarda idi. Vurgulanması gereken, önceki bazı epidemiyolojik çalışmaların Türk toplumunda YYL-k düzeyinin "genetik olarak" düşük olduğunu iddia etmesine rağmen çalışma grubunda YYL-k'nin düşük olmamasıdır. Bu bulgu değerlendirilen grubun yaşam şeklinin olumlu özelliklerine bağlı olabilir. Bununla birlikte Türkiye'de yapılan bazı yeni çalışmalar YYL-k seviyelerini sanıldığından daha yüksek bulmuşlardır. Bu konunun özellikle sedanter yaşam tarzı olmayan belli yaş aralığındaki gruplarda aydınlatılmasına ihtiyaç vardır.

🔖

Cite This Article

ÇÖL, M., ÖZCEM, B., KÜÇÜK, U., TAPAN, S., KABUL, H. K. (2022). Yirmi-elli yaş arası sağlıklı erkeklerde geleneksel koroner risk faktörleri: Yüksek yoğunluklu lipoprotein kolesterol üzerine odaklanma. Anadolu Kardiyoloji Dergisi, Cilt: 13 - Sayı: 6, 552–558. https://ajindex.com/articles/436267

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. World Health Organization in Collaboration with World Heart Federation and World Stroke Organisation. Global Atlas on cardiovascular disease prevention and control. 2011 France. http:// whqlibdoc.who.int/publications/2011/9789241564373_eng.pdf 2. Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006
  2. [CrossRef] 3. Manuel DG, Lim J, Tanuseputro P Anderson GM, Alter DA, Laupacis A, et al. Revisiting Rose: strategies for reducing coronary heart disease. BMJ 2006
  3. [CrossRef] 4. Assmann G, Schulte H, von Eckardstein A, Huang Y. High-density lipoprotein cholesterol as a predictor of coronary heart disease risk. The PROCAM experience and pathophysiological implications for reverse cholesterol transport. Atherosclerosis 1996
  4. 124 Suppl: S11-20. [CrossRef] 5. Sacks FM. The role of high-density lipoprotein (HDL) cholesterol in the prevention and treatment of coronary heart disease: Expert group recommendations. Am J Cardiol 2002
  5. [CrossRef] 6. Mahley RW, Palaoğlu KE, Atak Z, Dawson-Pepin J, Langlois AM, Cheung V, et al. Turkish Heart Study: lipids, lipoproteins, and apolipoproteins. J Lipid Res1995
  6. Onat A, Yıldırım B, Uslu N, Gürbüz N, Keleş I, Çetinkaya A, et al. Investigations plasma lipoproteins and apolipoproteins in turkish adults: overall levels, associations with other risk parameters and HDL role as a marker of 's coronary risk in women. Türk Kardiyol Dern Arş 1999
  7. Barçın C, Tapan S, Kurşaklıoğlu H, Iyisoy I, Köse S, Kılıç S, et al. Coronary risk factors in young and healthy Turkish males: a cross- sectional analysis. Türk Kardiyol Dern Arş 2005
  8. Chapman MJ, Ginsberg HN, Amarenco P Andreotti F Boren J, Catapano AL, et al. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur Heart J 2011
  9. [CrossRef] 10. Nicholls SJ, Uno K, Tuzcu EM, Nissen SE. Lessons from coronary intravascular ultrasound on the importance of raising high-density lipoprotein cholesterol. Curr Atheroscler Rep 2010
  10. [CrossRef] 11. Mackey RH, Greenland P Goff DC Jr, Lloyd-Jones D, Sibley CT, Mora S. High-density lipoprotein cholesterol and particle concentrations, carotid atherosclerosis, and coronary events: MESA (multi-ethnic study of atherosclerosis).