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Journals / Anadolu Kardiyoloji Dergisi / 2013 / Cilt: 13 - Sayı: 5

Aort kapak sklerozu ile damarsal hasarı gösteren farklı parametreler arasındaki ilişki: gözlemsel bir çalışma

Relationship between aortic valve sclerosis and different vascular damage markers: an observational study

Mustafa Tarık AĞAÇ
Zeydin ACAR
Hakan ERKAN
Ayça KORKMAZ ATA
Şükrü ÇELİK
Levent KORKMAZ
Pages
452–456
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

But IMT was significantly higher in AVS group than in control one (0.76 mm±0.17 vs 0.6 mm±0.16; p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Although aortic valve sclerosis (AVS) and atherosclerosis may share same atherosclerotic process, there is still a controversy whether AVS may be related to atherosclerotic and nonatherosclerotic processes.
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Key Findings & Data:Methods: In this cross-sectional and observational study, we enrolled 60 patients diagnosed with AVS and risk factor matched 76 subjects without AVS.
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Conclusion & Impact:But IMT was significantly higher in AVS group than in control one (0.76 mm±0.17 vs 0.6 mm±0.16; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Although aortic valve sclerosis (AVS) and atherosclerosis may share same atherosclerotic process, there is still a controversy whether AVS may be related to atherosclerotic and nonatherosclerotic processes. The purpose of present study was to investigate this relation. Methods: In this cross-sectional and observational study, we enrolled 60 patients diagnosed with AVS and risk factor matched 76 subjects without AVS. Applanation tonometry was applied to assess the augmentation index and aortic pulse-wave velocity (PWV). Control and AVS group were examined by B-mode ultrasound to measure the intima-media thickness (IMT). Continuous variables were compared using unpaired t-test and Mann-Whitney U test. Logistic regression analysis was performed in order to find independent predictors of AVS. Results: PWV and augmentation index did not differ between control and AVS groups (11.2±3.6 vs 12±3.2, p=0.18 and 26±7.6 vs 27±9.8, p=0.2 respectively). But IMT was significantly higher in AVS group than in control one (0.76 mm±0.17 vs 0.6 mm±0.16; p

Özet

Amaç: Aort kapak sklerozu (AKS) ile atheroklerosis arasında bir ilişki olduğu düşünülse de AKS'nin patogenezinde nonaterosklerotik procesin rol alıp almadığı konusunda yeterli bilgi bulunmamaktadır. Çalışmanın amacı bunu test etmekti. Yöntemler: Gözlemsel ve kesitsel çalışmamımızda AKS'si olan 60 hasta ve kardiyovasküler risk faktörleri eşleştirilmiş 76 kontrol grubu çalışmaya alınmıştır. Aplanasyon tonometri ile puls-dalga hız (PWV) ve augmentasyon indeksi değerlendirildi. B-mode ultrasound ile intima-medya kalınlığı (İMK) değerlendirildi. Eşleştirilmemiş t / Mann-Whitney U testleri ve lojistik regresyon analiz yapıldı. Bulgular: Kontrol ve AVS grubları arasında augmentasyon indeksi ve PWV açısından bir fark yoktu (11,2±3,6-12±3,2, P=0,18 ve 26±7, 6-27±9,8, P=0,2, sırasıyla). Fakat İMK AVS'li grupta anlamlı olarak yüksek bulundu (0,76 mm±0,17-0,6 mm±0,16; P

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Cite This Article

AĞAÇ, M. T., ACAR, Z., ERKAN, H., ATA, A. K., ÇELİK, Ş., KORKMAZ, L. (2022). Aort kapak sklerozu ile damarsal hasarı gösteren farklı parametreler arasındaki ilişki: gözlemsel bir çalışma. Anadolu Kardiyoloji Dergisi, Cilt: 13 - Sayı: 5, 452–456. https://ajindex.com/articles/436244

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