Journals / Anadolu Kardiyoloji Dergisi / 2013 / Cilt: 13 - Sayı: 8

Polikistik over sendromlu hastalarda subklinik sol ventrikül disfonksiyonu: Gözlemsel bir çalışma

Subclinical left ventricular dysfunction in women with polycystic ovary syndrome: An observational study

Pages
784–790
Publication Date
2022-10-10
DOI
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Results: The early mitral inflow deceleration time (DT), isovolumetric relaxation time (IVRT) and E/Em ratio were increased in the PCOS group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Cardiac involvement has been increasingly recognized in patients with polycystic ovary syndrome (PCOS).
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Key Findings & Data:Identification of the ear- liest asymptomatic impairment of left ventricular (LV) performance may be important in preventing progression to overt heart failure.
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Conclusion & Impact:Results: The early mitral inflow deceleration time (DT), isovolumetric relaxation time (IVRT) and E/Em ratio were increased in the PCOS group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Cardiac involvement has been increasingly recognized in patients with polycystic ovary syndrome (PCOS). Identification of the ear- liest asymptomatic impairment of left ventricular (LV) performance may be important in preventing progression to overt heart failure. Our aim was to investigate LV function with different echocardiographic techniques in patients with PCOS. Methods: Thirty patients with PCOS and 30 age and body mass index matched healthy subjects were enrolled to this cross-sectional observa- tional study. All subjects underwent echocardiography for assessment of resting LV function as well as two-dimensional speckle tracking echocar- diography (2D-STE) and real-time three-dimensional echocardiography (3D-Echo). Global longitudinal strain (GLS) was calculated from 3 standard apical views using 2D-STE. Student t-test, Chi-square test, Pearson’s, and Spearman’s correlation analysis were used for statistical analysis. Results: The early mitral inflow deceleration time (DT), isovolumetric relaxation time (IVRT) and E/Em ratio were increased in the PCOS group (p

Özet

Amaç: Polikistik over sendromlu (PKOS) hastalarda kardiyak tutulumun olduğu kabul edilmektedir. Asemptomatik sol ventrikül (SV) fonksiyonla- rındaki bozulmanın erken tespiti kalp yetersizliğine gidişatın önlenmesinde önemli olabilir. Amacımız PKOS hastalarında farklı ekokardiyografik teknikler kullanarak SV fonksiyonlarını araştırmaktır. Yöntemler: Kesitsel ve gözlemsel calışmamıza, polikistik over sendromlu 30 hasta ve demografik özellikleri benzer 30 sağlıklı kadın dahil edildi. İstirahat SV fonksiyonlarının değerlendirilmesinde standart transtorasik ekokardiyografi yanında, iki boyutlu benek izleme ekokardiyografi (2B-BIE) ve üç boyutlu ekokardiyografi (3B-Eko) bakıldı. SV hacimleri ve ejeksiyon fraksiyonu ölçümü 3B-Eko ile yapıldı. Apikal görüntülerden 2B-BIE tekniği kullanılarak global longitüdinal strain (GLS) değerleri hesaplandı. İstatistiksel analizde; Student t-testi, Ki-kare testi, Pearson ve Spearman korelasyon analizleri kullanıldı. Bulgular: Polikistik over sendromlu hastalarda mitral E dalgası deselerasyon zamanı (DT), E/Em oranı ve izovolümetrik relaksasyon zamanının (IVRT) kontrol grubuna göre artmış olduğu görüldü (tümü için p

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Cite This Article

KUL, Ş., ERTAŞ, G., ERGELEN, M., TURFAN, M., ERDOĞAN, E., TASAL, A., BACAKSIZ, A., BATMAZ, G., UYAREL, H., GÖKTEKİN, Ö., SÖNMEZ, O., AKKAYA, M., VATANKULU, M. A. (2022). Polikistik over sendromlu hastalarda subklinik sol ventrikül disfonksiyonu: Gözlemsel bir çalışma. Anadolu Kardiyoloji Dergisi, Cilt: 13 - Sayı: 8, 784–790. https://ajindex.com/articles/436215

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