Journals / Anadolu Kardiyoloji Dergisi / 2013 / Cilt: 13 - Sayı: 6

Yetişkinlerde tetraloji Fallot onarımından epey sonra sağ ventrikül sistolik fonksiyonunun Doppler kaynaklı strain ve strain rate görüntülemesi ile değerlendirilmesi: Gözlemsel bir çalışma

Doppler-derived strain and strain rate imaging assessment of right ventricular systolic function in adults late after tetralogy of Fallot repair: an observational study

Pages
536–542
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These quantitative methods improved the assessment of the RV function and served as an additional method to follow up patients with contraindications to CMR.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease.
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Key Findings & Data:We sought to evaluate the RV systolic function via CMR and compare it with Doppler-derived strain(S) and strain rate (SR) imaging in patients with repaired TOF.
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Conclusion & Impact:These quantitative methods improved the assessment of the RV function and served as an additional method to follow up patients with contraindications to CMR.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease. Today, we are faced with an increasing number of patients with residual pulmonary regurgitation (PR) late after TOF repair. The right ventricular (RV) volumes and function are among the most important factors influencing clinical decision-making. Cardiac magnetic resonance (CMR) is the gold standard method for the quantitative assess- ment of the RV function; it is, however, expensive for routine clinical follow-up and sometimes is contraindicated. We sought to evaluate the RV systolic function via CMR and compare it with Doppler-derived strain(S) and strain rate (SR) imaging in patients with repaired TOF. Methods: In an observational cross-sectional study, 70 patients (22 women, mean age=22±4.9 years) late after TOF repair with severe PR were evaluated. Peak systolic strain and SR in the basal, mid, and apical segments of RV free wall (RVFW) were measured and compared with the RV function measured in the short-axis cine MR. Associations between RVEF and S/SR, investigated by ordinal logistic regression models. Results: Significant association was observed between RV function and mean S of all the three segments of the RVFW segments [OR (CI95%): 1.17 (1.05-1.31)]. Association between RV function and mean SR of all the three segments of the RVFW segments was borderline significant [OR (CI95%): 1.7 (0.97-2.93)]. Conclusion: There was a significant correlation between the Doppler-derived mean strain of RVFW and the RV function measured by CMR in adults late after TOF repair. These quantitative methods improved the assessment of the RV function and served as an additional method to follow up patients with contraindications to CMR.

Özet

Amaç: Fallot tetralojisi (TOF) siyanotik konjenital kalp hastalığının en sık görülen şeklidir. Günümüzde, TOF onarımı sonrası rezidüel pulmoner yetersizliği (PR) olan hastaların sayılarında artış ile karşı karşıyayız. Sağ ventrikül (RV) hacim ve fonksiyonu klinik karar vermeyi etkileyen en önemli faktörler arasındadır. Kardiyak manyetik rezonans (CMR) RV fonksiyonunun nicel değerlendirilmesi için altın standart yöntemdir; ancak, rutin klinik takip için pahalıdır ve bazen kontrendikedir. Biz TOF onarımı yapılan hastalarda CMR ile RV sistolik fonksiyonu değerlendirmesini Doppler kaynaklı strain (S) ve strain rate (SR) görüntülemesi ile karşılaştırmaya çalıştık. Yöntemler: Kesitsel bir çalışmada, TOF onarımından epey sonra şiddetli PR’li 70 hasta (22 kadın, ortalama yaş=22±4,9) değerlendirildi. RV serbest duvarının bazal, mid ve apikal segmentlerinde peak sistolik strain ve SR ölçülerek kısa-aks sine MR da ölçülen RV fonksiyonu ile karşılaştırıldı. RVEF ve S/SR arasındaki ilişkiler sıra lojistik regresyon modelleri ile incelendi. Bulgular: RV fonksiyonu ve RVFW segmentlerinin üç segmentinin hepsinin S ortalaması arasında önemli bir ilişki gözlemlendi (OR [CI%95]: 1.17 [1,05- 1,31]). RV fonksiyonu ve RVFW segmentlerinin her üç segmentinin SR ortalaması arasındaki bağlantı sınırda önemliydi (OR [CI%95]: 1,7 [0,97-2,93]). Sonuç: TOF onarımı görmüş yetişkinlerde Doppler kaynaklı RVFW ortalama strain ile CMR ile ölçülmüş RV fonksiyonu arasında önemli bir ilişki vardı. Bu nicel yöntemler RV fonksiyonunun değerlendirilmesini geliştirmiş ve CMR kontrendikasyonu olan hastaları takip etmek için ek bir yöntem olarak yer almıştır.

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Cite This Article

KYAVAR, M., KHAJALI, Z., MADADI, S., EBRAHIMI, L., SANI, Z. A., SADEGHPOUR, A. (2022). Yetişkinlerde tetraloji Fallot onarımından epey sonra sağ ventrikül sistolik fonksiyonunun Doppler kaynaklı strain ve strain rate görüntülemesi ile değerlendirilmesi: Gözlemsel bir çalışma. Anadolu Kardiyoloji Dergisi, Cilt: 13 - Sayı: 6, 536–542. https://ajindex.com/articles/436171

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