SavedAdd your journal

Journals / Akdeniz Tıp Dergisi / 2021 / Cilt: 7 - Sayı: 3

Guillain Barré Syndrome in a Multiple Myeloma Patient After the Autologous Transplantation: A Case Report

Otolog Transplantasyon Sonrası Multipl Miyelom Hastasında Guillain Barré Sendromu: Olgu Sunumu

İnci ALACACIOĞLU
Fatih DEMİRKAN
Güner Hayri ÖZSAN
Ahmet SEYHANLI
İsmail SELİMOĞLU
Pages
479–482
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Herein a case of multiple myeloma developing Guillain-Barre syndrome after autologous transplantation improved by plasmapheresis is presented.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Guillain-Barre syndrome (GBS) is an immune-mediated peripheral neuropathy involving multiple nerve roots and peripheral nerves.
📊
Key Findings & Data:The pathogenesis remains incompletely understood, and etiology is unclear.
💡
Conclusion & Impact:Herein a case of multiple myeloma developing Guillain-Barre syndrome after autologous transplantation improved by plasmapheresis is presented.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Guillan Barre sendromu · Multiple myeloma · Periferik otolog kök hücre nakli

Abstract

Guillain-Barre syndrome (GBS) is an immune-mediated peripheral neuropathy involving multiple nerve roots and peripheral nerves. The pathogenesis remains incompletely understood, and etiology is unclear. Infections, malignancies, vaccination, and bone marrow transplantation have been accused. Plasmapheresis and intravenous immunoglobulin can be used for treatment. Multiple myeloma is a malignant disease characterized by an abnormal proliferation of clonal plasma cells. Chemotherapy and autologous transplantation are primary therapies for multiple myeloma. Herein a case of multiple myeloma developing Guillain-Barre syndrome after autologous transplantation improved by plasmapheresis is presented.

Özet

Guillain-Barre sendromu (GBS), çoklu sinir köklerini ve periferik sinirleri etkileyen bağışıklık aracılı bir periferik nöropatidir. Patogenez tam olarak anlaşılamamıştır ve etiyolojisi belirsizdir. Enfeksiyonlar, maligniteler, aşılama ve kemik iliği nakli suçlanmıştır. Plazmaferez ve intravenöz immünoglobulin tedavi için kullanılabilir. Multipl miyelom, klonal plazma hücrelerinin anormal proliferasyonu ile karakterize malign bir hastalıktır. Kemoterapi ve otolog transplantasyon, multipl miyelom için birincil tedavilerdir. Burada plazmaferez ile düzelen otolog transplantasyon sonrası Guillain-Barre sendromu gelişen multipl miyelom olgusu sunulmuştur.

🔖

Cite This Article

ALACACIOĞLU, İ., DEMİRKAN, F., ÖZSAN, G. H., SEYHANLI, A., SELİMOĞLU, İ. (2022). Guillain Barré Syndrome in a Multiple Myeloma Patient After the Autologous Transplantation: A Case Report. Akdeniz Tıp Dergisi, Cilt: 7 - Sayı: 3, 479–482. https://ajindex.com/articles/434225

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Kyle R, Rajkumar SV: Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma. Leukemia 2009, 23(1):3-9
  2. Morgan G, Davies F: Evolving treatment strategies for myeloma. British journal of cancer 2005, 92(2):217-221
  3. Al Hamed R, Bazarbachi AH, Malard F, Harousseau J-L, Mohty M: Current status of autologous stem cell transplantation for multiple myeloma. Blood cancer journal 2019, 9(4):1-10
  4. Graff TM, Singavi AK, Schmidt W, Eastwood D, Drobyski WR, Horowitz M, Palmer J, Pasquini M, Rizzo DJ, Saber W: Safety of outpatient autologous hematopoietic cell transplantation for multiple myeloma and lymphoma. Bone marrow transplantation 2015, 50(7):947-953
  5. Ruzhansky KM, Brannagan III TH: Neuromuscular complications of hematopoietic stem cell transplantation. Muscle & nerve 2015, 52(4):480-487
  6. Castro LH, Ropper AH: Human immune globulin infusion in Guillain‐Barré syndrome: Worsening during and after treatment. Neurology 1993, 43(5):1034-1034
  7. Durrheim DN: Guillain–Barré Syndrome. Hospital (Burkina Faso) 2004, 160:559-562
  8. Fujisaki G, Kami M, Murashige N, Kishi Y, Hori A, Chizuka A, Ugawa Y, Kobayashi K, Tanosaki R: Guillain–Barré syndrome associated with rapid immune reconstitution following allogeneic hematopoietic stem cell transplantation. Bone marrow transplantation 2006, 37(6):617-619
  9. Khouri J, Majhail NS: Advances in delivery of ambulatory autologous stem cell transplantation for multiple myeloma. Current opinion in supportive and palliative care 2017, 11(4):361-365
  10. Xu Y-L, Zhao W-H, Tang Z-Y, Li Z-Q, Long Y, Cheng P, Luo J: Guillain-Barre syndrome in a patient with multiple myeloma after bortezomib therapy: A case report. World Journal of Clinical Cases 2019, 7(18):2905
  11. Hadden R, Karch H, Hartung H-P, Zielasek J, Weissbrich B, Schubert J, Weishaupt A, Cornblath D, Swan A, Hughes R: Preceding infections, immune factors, and outcome in Guillain–Barré syndrome. Neurology 2001, 56(6):758-765
  12. Jacobs B, Rothbarth P, Van der Meché F, Herbrink P, Schmitz P, De Klerk M, Van Doorn P: The spectrum of antecedent infections in Guillain-Barré syndrome: a case-control study. Neurology 1998, 51(4):1110-1115
  13. Orlikowski D, Porcher R, Sivadon-Tardy V, Quincampoix J-C, Raphaël J-C, Durand M-C, Sharshar T, Roussi J, Caudie C, Annane D: Guillain–Barré syndrome following primary cytomegalovirus infection: a prospective cohort study. Clinical infectious diseases 2011, 52(7):837-844
  14. Kang J-H,