Journals / Akademik Gıda / 2019 / Cilt: 17 - Sayı: 1

Mechanism of Antimicrobial Resistance in Bacterial Biofilms

Bakteriyel Biyofilmlerdeki Antimikrobiyel Direnç Mekanizması

Pages
131–139
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the present review, the resistance mechanisms of bacterial biofilms in food industry against antimicrobial agents are focused.

📌 3 Key Takeaways

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Objective & Hypothesis:Biofilm is defined as a community in which microorganisms adhere to a living or inanimate surface, embedded in a gelatinous layer in a self-produced matrix of extrapolymeric substances, adhered to each other, to a solid surface or to an interface.
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Key Findings & Data:In food industry, biofilm formation is undesirable as they cause food spoilage, damages in food processing equipment and diseases due to pathogenic contamination.
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Conclusion & Impact:In the present review, the resistance mechanisms of bacterial biofilms in food industry against antimicrobial agents are focused.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Biofilm is defined as a community in which microorganisms adhere to a living or inanimate surface, embedded in a gelatinous layer in a self-produced matrix of extrapolymeric substances, adhered to each other, to a solid surface or to an interface. In food industry, biofilm formation is undesirable as they cause food spoilage, damages in food processing equipment and diseases due to pathogenic contamination. Biofilms are more resistant to antimicrobial agents than planktonic cells. There are various possible mechanisms responsible for antimicrobial resistance of the bacteria in biofilms. The main factors that affect resistance mechanism in biofilms are characterized as exopolysaccharide matrix, enzymes, heterogeneity, cellular persistence, metabolic activity, genetic adaptation, quorum sensing, stress responses, outer membrane structure and efflux pumps. A whole understanding of resistance mechanisms can provide benefits to prevent and control biofilm formation. As a result, researchers should initially focus on the mechanisms of resistance for effective biofilm control and then protective measures must be taken. In the present review, the resistance mechanisms of bacterial biofilms in food industry against antimicrobial agents are focused.

Özet

Biyofilm, mikroorganizmaların canlı veya cansız bir yüzeye yapışarak kendi ürettikleri ekzopolimerik yapıda jelsi birtabaka içine gömülü halde birbirlerine, bir katı yüzeye ya da bir ara yüzeye tutunarak oluşturdukları topluluk olaraktanımlanır. Gıda endüstrisinde biyofilm oluşumu gıdalarda bozulmalara, gıda işleme ekipmanlarında hasarlara vepatojen kontaminasyonları ile hastalıklara neden olduğu için istenmeyen bir durumdur. Biyofilmler antimikrobiyelmaddelere karşı planktonik hücrelerden daha dirençlidirler. Biyofilmlerdeki bakterilerin antimikrobiyellere karşıgösterdikleri dirençten birçok olası mekanizma sorumludur. Biyofilmlerdeki direnç mekanizmasını etkileyen başlıcafaktörler ekzopolisakkarit matriksi, enzimler, heterojenlik, hücresel persistans, metabolik aktivite, genetik adaptasyon,kitle algılama, stres cevapları, dış membran yapısı ve sızdırma pompaları’dır. Direnç mekanizmalarının tam olarakanlaşılması biyofilm oluşumunun önlenmesi ve kontrol edilmesinde fayda sağlayacaktır. Sonuç olarak etkili bir biyofilmkontrolü için araştırmacılar öncelikle direnç mekanizmaları üzerinde yoğunlaşmalı ve daha sonra koruyucu önlemlerinalınması gerekmektedir. Bu derlemede, gıda endüstrisindeki bakteriyel biyofilmlerin antimikrobiyel maddelere karşıgösterdikleri direnç mekanizması üzerinde durulmuştur

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Cite This Article

TURHAN, E. Ü., ERGİNKAYA, Z. (2022). Mechanism of Antimicrobial Resistance in Bacterial Biofilms. Akademik Gıda, Cilt: 17 - Sayı: 1, 131–139. https://ajindex.com/articles/432530

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