Journals / Adnan Menderes Üniversitesi Ziraat Fakültesi Dergisi / 2018 / Cilt: 15 - Sayı: 1

Formation of Bioactive Peptides in Dairy Products and Functional Properties

Süt Ürünlerinde Biyoaktif Peptitlerin Oluşumu ve Fonksiyonel Özellikleri

Pages
115–120
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, the formation of bioactive peptides and their functional properties in dairy products are evaluated.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Bioactive peptides are defined as specific protein fragments having positive impact on body functions and health.
📊
Key Findings & Data:Milk proteins are known as rich source of bioactive peptides.
💡
Conclusion & Impact:In this review, the formation of bioactive peptides and their functional properties in dairy products are evaluated.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Bioactive peptides are defined as specific protein fragments having positive impact on body functions and health. Milk proteins are known as rich source of bioactive peptides. Biologically active peptides can be produced from milk by enzymatic hydrolysis of digestive enzymes, fermentation of milk with proteolytic starter cultures and proteolysis by enzymes. The peptides released from main protein molecule in dairy products, can function as a hormone-like regulatory component in the body and can show various biological activities such as antihypertensive, antioxidative, opioid, antimicrobial and immune regulation effect in the body depending on the amino acid size and content. Angiotensin converting enzyme (ACE) inhibitor peptides known as antihypertensive peptides are the most studied subjects. Milk-derived peptide fractions can also prevent some chronic heart diseases such as arteriosclerosis and phlebolite; by binding free radicals and by oxidative stress-inhibiting action. In this review, the formation of bioactive peptides and their functional properties in dairy products are evaluated.

Özet

Biyoaktif peptitler, vücut fonksiyonları ve sağlık üzerinde olumlu etkileri olan proteinlerin spesifik parçalanma ürünleri olarak tanımlanmaktadır. Süt proteinleri bioaktif peptitler için önemli bir kaynak olarak görülmektedir. Süt proteinlerinden biyoaktif peptitler, sindirim enzimleri aracılığıyla enzimatik hidroliz, proteolitik aktiviteye sahip starter kültürler aracılığıyla fermentasyon ve enzimler ile proteoliz sırasında açığa çıkabilmektedir. Süt ürünlerinde ana protein molekülünden açığa çıkan söz konusu peptitler, vücut içinde hormon benzeri düzenleyici bileşen olarak görev alabilmekte ve amino asit boyutu ve içeriğine bağlı olarak vücutta antihipertansif, antioksidatif, opioid, antimikrobiyal ve bağışıklık düzenleme gibi birçok farklı biyolojik aktivite gösterebilmektedir. Antihipertansif peptitler olarak da bilinen anjiyotensin dönüştürücü enzim (ACE, Angiotensin converting enzyme) inhibitör peptitleri en fazla çalışma konusu olanlardır. Süt kaynaklı peptit fraksiyonları serbest radikalleri bağlayıcı ve oksidatif stresi önleyici etki göstererek, damar sertleşmesi ve damar tıkanıklığı gibi bazı kronik kalp rahatsızlıklarını da önleyebilmektedir. Bu derlemede, süt ürünlerinde bioaktif peptitlerin oluşumu ve fonksiyonel özellikleri değerlendirilmektedir.

🔖

Cite This Article

ŞANLI, T., AY, C. (2022). Formation of Bioactive Peptides in Dairy Products and Functional Properties. Adnan Menderes Üniversitesi Ziraat Fakültesi Dergisi, Cilt: 15 - Sayı: 1, 115–120. https://ajindex.com/articles/429270

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Barac M, Smiljanic M, Zilic S, Pesic M, Stanojevic S, Vasic M, Vucic T (2016) Protein profiles and total antioxidant capacity of water soluble and insoluble protein fractions of white cow cheese at different stage of ripening, Mljekarstvo 66(3):187-197.
  2. Beermann C, Hartung J (2013) Physiological Properties of Milk Ingredients Released by Fermentation. Food and Function 4: 185-199.
  3. Bütikofer U, Meyer J, Sieber R, Walther B, Wechsler D (2008) Occurence of the Angiotensin-Converting Enzyme-Inhibiting Tripeptides Val-Pro-Pro and Ile- Pro-Pro in Different Cheese Varieties of Swiss Origin. Journal of Dairy Science 91(1):29-38.
  4. Choi J, Sabikhi L, Hassan A, Anand S. (2012) Bioactive Peptides in Dairy Products. International Journal of Dairy Technology 65(1): 1-12.
  5. Clare DA, Swaisgood HE (2000) Bioactive Milk Peptides: A Prospectus. Journal of Dairy Science 83: 1187- 1195. De Gobba,C, Espejo-Carpio FJ, Skibsted LH, Otte J (2014) Antioxidant peptides from goat milk protein fractions hydrolysed by two commercial proteases, International Dairy Journal 39:28-40.
  6. Dimitrov Z, Chorbadjiyska E, Gotova I, Pashova K, Ilieva S (2015) Selected adjunct cultures remarkably increase the content of bioactive peptides in Bulgarian white brined cheese, Biotechnology & Biotechnological Equipment 29(1):78-83.
  7. Donkor O, Henriksson A, Vasiljevic T, Shah NP (2007) Proteolytic Activity of Dairy Lactic Acid Bacteria and Probiotics as Determinant of Growth and in Vitro Angiotensin-Converting Enzyme Inhibitory Activity in Fermented Milk. Lait 86:21-38.
  8. Ebringer L, Ferenčík, M, Krajčovič J (2008) Beneficial Health Effects of Milk and Fermented Dairy Products. Folia Microbiol 53 (5): 378-394.
  9. Erkaya T, Şengül M (2015) Bioactivity of water soluble extracts and some characteristic of white cheese during the ripening period as effected by packaging type and adjunct cultures, Journal of Diary Research 82:47-55.
  10. Gill HS, Doull F, Rutherfurd KJ, Cross ML (2000) Immunoregulatory Peptides in Bovine Milk. British Journal of Nutrition 84: 111-117.
  11. Gomez-Ruiz JA, Ramos M, Recio I (2002) Angiotensin- Converting Enzyme-Inhibitory Peptides in Manchego Cheeses Manufactured with Different Starter Cultures, International Dairy Journal 12: 697-706.
  12. Gonzalez-Gonzalez CR, Tuohy KM, Jauregi P (2011) Production of Angiotensin-I- Converting Enzyme (ACE) Inhibitory Activity in Milk Fermented with Probiotic Strains: Effects of Calcium, pH and Peptides on the ACE-Inhibitory Activity. International Dairy Journal 21: 615