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Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2001 / Cilt: 9 - Sayı: 1

Coronary bypass surgery in glucose-6-phosphate dehydrogenase deficiency

Glukoz-6-fosfat dehidrogenaz eksikliğinde koroner bypass cerrahisi

İlhan GÖLBAŞI
Nursel ŞAHİN
Ömer BAYEZİD
Ercan AKBULUT
Harun GÜLMEZ
Ayşen ŞAHİNOĞLU
Cengiz TÜRKAY
Pages
49–50
Publication Date
2022-09-02
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We think that open heart surgery can be performed succesfully with special attention in patients with G6PD deficiency.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In red cells, defense against oxidative damage is essentially dependent on glucose-6- phosphate dehydrogenase (G6PD) enzyme activity.
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Key Findings & Data:Hemolysis can be caused by oxidan agents generated during cardiopulmonary bypass and peroperative medications in G6PD deficiency.
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Conclusion & Impact:We think that open heart surgery can be performed succesfully with special attention in patients with G6PD deficiency.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In red cells, defense against oxidative damage is essentially dependent on glucose-6- phosphate dehydrogenase (G6PD) enzyme activity. Hemolysis can be caused by oxidan agents generated during cardiopulmonary bypass and peroperative medications in G6PD deficiency. The case of a 51 year-old male with G6PD deficiency underwent coronary bypass surgery. Intraoperative and postoperative course was uneventful and he was discharged on the eighth day. We think that open heart surgery can be performed succesfully with special attention in patients with G6PD deficiency.

Özet

Eritrositlerde oksidan hasara karşı savunma, esas olarak glukoz-6-fosfat dehidrogenaz (G6PD) aktivitesine bağlıdır. Bu enzimin eksikliğinde, kardiyopulmoner bypass esnasında gelişen oksidan ajanlar ve peroperatif medikasyonlar hemolitik krize neden olabilirler. G6PD eksikliği bulunan 51 yaşındaki erkek hastamıza koroner bypass ameliyatı yapıldı. İntraoperatif ve postoperatif takipde sorun olmadı ve postoperatif 8. günde taburcu edildi.

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Cite This Article

GÖLBAŞI, İ., ŞAHİN, N., BAYEZİD, Ö., AKBULUT, E., GÜLMEZ, H., ŞAHİNOĞLU, A., TÜRKAY, C. (2022). Coronary bypass surgery in glucose-6-phosphate dehydrogenase deficiency. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 9 - Sayı: 1, 49–50. https://ajindex.com/articles/425547

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