Journals / Laparoscopic Endoscopic Surgical Science / 2022 / Cilt: 29 - Sayı: 2

Incidence of lymphoid aggregates and associated factors in a large gastric biopsy series

Pages
61–64
Publication Date
2022-09-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: In our study, relatively young age, HP, and presence of inflammation were independent risk factors for lymphoid aggregates.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: Lymphoid aggregates (LA) in gastric biopsies have traditionally been linked to Helicobacter pylori (HP) gastritis and other inflammatory and neoplastic conditions.
📊
Key Findings & Data:Materials and Methods: Endoscopic gastric mucosal biopsies taken from 1427 adult patients due to dyspeptic complaints were evaluated in terms of the relationship of LA with age, gender, HP, inflammation, gastric activity, and intestinal metaplasia (IM).
💡
Conclusion & Impact:Conclusion: In our study, relatively young age, HP, and presence of inflammation were independent risk factors for lymphoid aggregates.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Lymphoid aggregates (LA) in gastric biopsies have traditionally been linked to Helicobacter pylori (HP) gastritis and other inflammatory and neoplastic conditions. In the literature review on this subject, it is seen that the studies are limited and the number of patients in the studies is low. The aim of this study was to evaluate the relationship between the incidence of LA and patient’s age, gender, HP, and other gastric mucosal pathologies in pathological examinations of gastric mucosal biopsies in a large series. Materials and Methods: Endoscopic gastric mucosal biopsies taken from 1427 adult patients due to dyspeptic complaints were evaluated in terms of the relationship of LA with age, gender, HP, inflammation, gastric activity, and intestinal metaplasia (IM). Results: LA was associated with HP positivity, age, inflammation, activity, and IM. No relationship was found with gender. Conclusion: In our study, relatively young age, HP, and presence of inflammation were independent risk factors for lymphoid aggregates.

🔖

Cite This Article

GÜLMEZ, S., SÖNMEZ, M. R. (2022). Incidence of lymphoid aggregates and associated factors in a large gastric biopsy series. Laparoscopic Endoscopic Surgical Science, Cilt: 29 - Sayı: 2, 61–64. https://ajindex.com/articles/423515

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Zinzan PL. Non-gastrointestinal MALT lymphoma. Haematologica 1999;84:81-4
  2. Bashiri H, Esmaeilzadeh A, Vossoughinia H, Ghaffarzadegan K, Raziei HR, Bozorgomid A. Association between gastric lymphoid follicles (Precursor of malt lymphomas) and h. pylori infection at a referral hospital in Iran. Clin Exp Gastroenterol 2019;12:409–13
  3. Owen D. Normal histology of the stomach. Am J Surg Pathol 1986;10:48–61
  4. Eidt S, Stolte M. Prevalence of lymphoid follicles and aggregates in Helicobacter pylori gastritis in antral and body mucosa. J Clin Pathol 1993;46:832–5
  5. Zaitoun AM. The prevalence of lymphoid follicles in Helicobacter pylori–associated gastritis in patients with ulcers and non–ulcer dyspepsia. J Clin Pathol 1995;48:325–9
  6. Genta RM, Hammer HW, Graham DY, et al. Gastric lymphoid follicles in Helicobacter pylori infection: frequency, distribution, and response to triple therapy. Hum Pathol 1993;24:577–83
  7. Fox JG, Correa P, Taylor NS, Zavala D, Fontham E, Janney F, et al. Campylobacter pylori–associated gastritis and immune response in a population at increased risk of gastric carcinoma. Am J Gastroenterol 1989;84:775–81
  8. Carpentieri DF, Wenner W, Liquornik K, Ruchelli E. Significance of lymphoid follicles and aggregates in gastric mucosa of children. Pediatr Dev Pathol 2000;3:177–9
  9. Fakhro ARE, Bahaa El–Din AF, Farid IMA, Jamsheer HM. The association between Helicobacter pylori infection and lymphoid reaction in patients suffering from dyspepsia in Bahrain. Saudi J Gastroenterol 1999;5:129–33
  10. Jaśkiewicz K, Kobierska G. Lymphoid aggregates in gastric biopsies: relationship to other mucosal lesions. Arch Immunol Ther Exp (Warsz) 2000;48:201–4
  11. Genta RM, Hamner HW, Graham DY. Gastric lymphoid follicles in Helicobacter pylori infection: frequency, distribution, and response to triple therapy. Hum Pathol 1993;24:577–83
  12. Strickland RG, Mackay IR. A reappraisal of the nature and significance of chronic atrophic gastritis. Am J Dig Dis. 1973;18:426–40
  13. Jaśkiewicz K, Louw J. Long–term histologic consequences of suppression/eradication of Helicobacter pylori. Dig Dis Sci 1993;38:937–43
  14. Hauke C, Grabner W, Grosse M, Stolte M. Lymph follicle formation and development of intestinal metaplasia in antrum mucosa as a reaction to Helicobacter pylori infection. Leber Magen Darm 1991;21:156–60
  15. Genta RM, Graham DY. Comparison of biopsy sites for the histopathologic diagnosis of Helicobacter pylori: a topographic study of H. p