Journals / Düzce Tıp Fakültesi Dergisi / 2010 / Cilt: 12 - Sayı: 3

Effects Of Oral Carbamazepine With 2% Lidocaine On Maxillary And Mandibular Nerve Blocks In Trigeminal Neuralgia

Trigeminal Nevraljide Oral Karbamazepin ile Birlikte %2 Lidokain ile Uygulanan Maksiler ve Mandibuler Sinir Bloklarının Etkileri

Pages
19–23
Publication Date
2010-12-01
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Favorable results areobtained in both the short and long–term, and notable increases are observed in the comfort andquality of life of patients

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: We evaluated the therapeutic efficacy of associating the oral administration ofcarbamazepine with 2% lidocaine for maxillary and mandibular nerve blocks in acute and longterm pain relief of trigeminal neuralgia in this retrospective study.Methods: A total of 13 patients (9 men and 4 women), with trigeminal neuralgia aged between34 and 91 years (Mean age 53±13.39), and who applied to our hospitals Pain Unit between July2007-July 2009 were included in this study.
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Key Findings & Data:The records of 13 patients suffering pain due totrigeminal neuralgia were examined; pain free periods, treatment success, side effects, andrecurrence were recorded.Results: At the end of a 5-week treatment period, pain relapses ceased in all patients.
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Conclusion & Impact:Favorable results areobtained in both the short and long–term, and notable increases are observed in the comfort andquality of life of patients
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Trigeminal nevralji · Karbamazepin · Lidokain

Abstract

Purpose: We evaluated the therapeutic efficacy of associating the oral administration ofcarbamazepine with 2% lidocaine for maxillary and mandibular nerve blocks in acute and longterm pain relief of trigeminal neuralgia in this retrospective study.Methods: A total of 13 patients (9 men and 4 women), with trigeminal neuralgia aged between34 and 91 years (Mean age 53±13.39), and who applied to our hospitals Pain Unit between July2007-July 2009 were included in this study. The records of 13 patients suffering pain due totrigeminal neuralgia were examined; pain free periods, treatment success, side effects, andrecurrence were recorded.Results: At the end of a 5-week treatment period, pain relapses ceased in all patients. Themajority of patients benefited remarkably from the treatment after week three. Pain recurred inone patient after one month and in two patients after six months. No relapse was observed inthe other 10 patients during the 12-month follow-up period. Conclusion: Pain episodes in trigeminal neuralgia cases may be controlled by maxillary andmandibular blocks applied with oral carbamazepine and 2% lidocaine. Favorable results areobtained in both the short and long–term, and notable increases are observed in the comfort andquality of life of patients

Özet

Amaç: Bu retrospektif çalışmada oral karbamazepin ile birlikte % 2 lidokain kullanılarakmaksiler ve mandibuler sinir bloğu uygulamasının akut ve uzun dönemde trigeminal nevraljiağrısı tedavisindeki etkilerinin araştırılması amaçlanmıştır.Yöntem: Trigeminal nevralji nedeniyle ağrısı olan ve Temmuz 2007-Temmuz 2009 tarihleriarasında hastanemiz Ağrı Ünitesine başvuran yaşları 34 ve 91 (Ortalama yaş 53±13.39) arasındadeğişen toplam 13 olgunun (9 erkek ve 4 kadın) kayıtları ağrısız geçen dönemleri, tedavibaşarısı, yan etkiler ve hastalığın tekrarlaması yönünden incelendi.Bulgular: 5 haftalık tedavi periyodu sonunda tüm olgularda ağrı atakları geçmişti. Olgularınçoğu 3. haftadan itibaren tedaviden belirgin şekilde fayda gördüler. Bir olguda 1 ay sonra, ikiolguda 6 ay sonra ağrı atakları tekrar başladı. Diğer 10 olguda 12 aylık izlemede ağrı atağıoluşmadı.Sonuç: Trigeminal nevralji hastalarının ağrı atakları oral karbamazepin ve % 2 lidokain ileuygulanan maksiler ve mandibuler sinir blokları ile kontrol altına alınabilmektedir. Bu tedaviyöntemi ile kısa ve uzun dönemde başarılı sonuçlar alınabilmekte ve olguların konforu ve hayatkalitesi yönünden dikkat çekici artışlar gözlenmektedir

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Cite This Article

KAPLAN, M., BAYKAL, M. (2010). Effects Of Oral Carbamazepine With 2% Lidocaine On Maxillary And Mandibular Nerve Blocks In Trigeminal Neuralgia. Düzce Tıp Fakültesi Dergisi, Cilt: 12 - Sayı: 3, 19–23. https://ajindex.com/articles/420253

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References (12)

  1. Bennetto L, Patel KN, Fuller G: Trigeminal neuralgia and its management. BMJ. 334: 201-205, 2007.
  2. Love S, Coakham HB: Trigeminal neuralgia pathology and pathogenesis. Brain. 124: 2347-2360, 2001.
  3. Chong MS, Bajwa ZH: Diagnosis and treatment of neuropathic pain. J Pain Sympt Manag. 25(5S): S4–S11, 2003.
  4. Zakrzewska JM, Lopez BC: Trigeminal and glossopharyngeal neuralgia. In: McMahon SB, Koltzenburg M (eds). Wall and Melzack's Textbook of Pain. 5th ed. Philadelphia. Churchill Livingstone Elsevier. pp 1001-1010, 2006.
  5. Wiffen PJ, McQuay HJ, Moore RA: Carbamazepine for acute and chronic pain. Cochrane Database Syst Rev. 20:CD005451, 2005.
  6. Solaro C, Uccelli MM, Uccelli A, Leandri M, Mancardi GL: Low-dose gabapentin combined with either iamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis. Eur Neurol. 44:45–48, 2000. Cheshire WP Jr: Defining the role for gabapentin in the treatment of trigeminal neuralgia: a retrospective study. J Pain. 3:137–142, 2002.
  7. McQuay H, Carroll D, Jadad RJ, Wiffen P, Moore A: Anticonvulsant drugs for management of pain: a systematic review. BMJ. 331:1047-1052, 1995.
  8. Taylor JC, Bauer S, Espir LE: Long term treatment of trigeminal neuralgia with carbamazepine. Postgrad Med J. 276:577-580, 1968.
  9. Han KR, Kim C, Chae YJ, Kim DW: Efficacy and safety of high concentration lidocaine for trigeminal neuralgia. Int J Clin Pract. 62(2):248-254, 2008. Breivik H. Local anesthetic blocks and epidurals. In: McMahon SB, Koltzenburg M (eds). Wall and Melzack’s Textbook of Pain. 5th ed. Philadelphia. Churchill Livingstone Elsevier. pp 903–925, 2006.
  10. Chapman CR, Syrjala KL: Measurement of pain. In: Loeser JD, Butler SH, Chapman CR, Turk DC (eds). Bonica’s Management of Pain. 3rd ed. Philadelphia. Lippincott Williams & Wilkins. pp 310–328, 2001. Brown DL. Maxillary block. In: Brown: Atlas of Regional Anesthesia. 3rd ed. Philadephia: Elsevier Saunders.pp 165-170, 2006. Brown DL. Mandibular block. In: Brown: Atlas of Regional Anesthesia. 3rd ed. Philadephia: Elsevier Saunders. pp 171- 176, 2006.
  11. Manchikanti L, Singh V, Trescot AM, Deer TR, Boswell MW. Guidelines for the practice of interventional techniques. In: Boswell MV, Cole BE(eds). Weiner’s Pain Management: A Practical Guide for Clinicians. 7th ed. Massachussets. CRC Press. pp 847–878, 2006.
  12. Stajcic Z, Todorovic L: Is carbamazepine less effective in the treatment of trigeminal neuralgia when prescribed by oral and maxillofacial surgeons? Anesth Prog. 44: 55-