Journals / Turkish Neurosurgery / 2011 / Cilt: 21 - Sayı: 2

Travmatik beyin hasarında intrakranial basınçla pulsatilite indeksinin korelasyonu

Correlation of pulsatility index with intracranial pressure in traumatic brain injury

Pages
210–215
DOI
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CONCLUSION: The strong correlation observed between ICP and PI through the management period of TBI patients can lead us to use TCD ultrasonography-derived PI as a guide if invasive monitoring is not available.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: In traumatic brain injury (TBI) patients, it is desired to monitor the intracranial pressure (ICP) to assess the cerebral haemodynamics and guide the therapy.
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Key Findings & Data:MATERIAL and METHODS: In 52 TBI patients with Glasgow Coma Scale (GCS) score < 9, invasive intracranial monitoring and TCD ultrasonography for PI were performed through five days.
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Conclusion & Impact:CONCLUSION: The strong correlation observed between ICP and PI through the management period of TBI patients can lead us to use TCD ultrasonography-derived PI as a guide if invasive monitoring is not available.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIM: In traumatic brain injury (TBI) patients, it is desired to monitor the intracranial pressure (ICP) to assess the cerebral haemodynamics and guide the therapy. The study was designed to see if the pulsatility index (PI) measured by transcranial Doppler ultrasonography (TCD) predicts information about ICP values. MATERIAL and METHODS: In 52 TBI patients with Glasgow Coma Scale (GCS) score < 9, invasive intracranial monitoring and TCD ultrasonography for PI were performed through five days. ICP, cerebral perfusion pressure (CPP), PI values were recorded and calculated. The correlation and regression analysis between ICP, PI and CPP were investigated in the whole group and in patients with a Glasgow Outcome Score (GOS) of 3-5. RESULTS: The decline in ICP and PI values was significant through five days. The correlation between ICP and PI was strongly significant (p < 0.0001) on days 1, 3 and 5. In patients with a GOS of 3-5, correlation of ICP and PI was also observed. The only significant correlation observed between CPP and PI was on day 5. CONCLUSION: The strong correlation observed between ICP and PI through the management period of TBI patients can lead us to use TCD ultrasonography-derived PI as a guide if invasive monitoring is not available.

Özet

AMAÇ: Travmatik beyin hasarında, tedavinin yönetilmesi ve intrakranial hemodinamiklerin değerlendirilmesi için intrakranial basıncın (ICP) monitörize edilmesi eğilimi vardır. Bu çalışma, transkranial Doppler ultrasonografi (TCD) ile ölçülen pulsatilite indeksi (PI) ölçümlerinin ICP değerleri hakkında ön bilgi verip veremediğinin araştırılması için dizayn edilmiştir. YÖNTEM ve GEREÇ: 5 gün boyunca Glasgow Koma Skoru <9 olan 52 TBI hastasında invaziv intrakranial monitörizasyon ve TCD ultrasonografi ile PI ölçümleri yapılmıştır. ICP, serebral perfüzyon basıncı (CPP) ve PI değerleri kayıt edilmiş ve değerlendirilmiştir. ICP, PI, ve CPP arasındaki korelasyon ve regresyon analizleri tüm grup için araştırılmıştır. BULGULAR: ICP ve PI değerlerindeki 5 gün boyunca olan azalma anlamlıdır. ICP ve PI arasındaki korelasyon 1, 3 ve 5. günlerde kuvvetli bir şekilde anlamlı bulunmuştur (p < 0,0001). Glasgow Outcome Skoru (GOS) 3-5 olan hastalarda da ICP ve PI değerlendirilmiştir. CPP ve PI arasındaki tek önemli korelasyon 5. günde tespit edilmiştir. SONUÇ: ICP ve PI arasında bulunan güçlü korelasyon, tedavinin yönetilmesi için invaziv monitörizasyon yapmanın mümkün olmadığı hastalarda PI değerlerinin kullanılmasına yönlendirebilir.

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Cite This Article

GURA, M., ELMACI, İ., SARI, R., COŞKUN, N. (2011). Travmatik beyin hasarında intrakranial basınçla pulsatilite indeksinin korelasyonu. Turkish Neurosurgery, Cilt: 21 - Sayı: 2, 210–215. https://ajindex.com/articles/417875

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