Journals / Göztepe Tıp Dergisi / 2012 / Cilt: 27 - Sayı: 3

İstanbul'da bir eğitim ve araştırma hastanesi yoğun bakım ünitesinde ventilator ilişkili pnömoninin etyoloji, insidans ve risk faktörleri

Etiology, incidence and risk factors of ventilator associated pneumonia in a training and research hospital intensive care unit in Istanbul

Pages
94–98
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Besides these, data about the potential microorganisms and resistance of antibiotics to them will guide the empirical therapy.

📌 3 Key Takeaways

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Objective & Hypothesis:In this prospective study, we aimed to identify the factors associated with the development of ventilator- associated pneumonia (VAP) and examine the etiology, and incidence of VAP.
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Key Findings & Data:Between November 2007 and June 2008, 148 patients who required mechanical ventilation for longer than 48 hours were evaluated.
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Conclusion & Impact:Besides these, data about the potential microorganisms and resistance of antibiotics to them will guide the empirical therapy.
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

In this prospective study, we aimed to identify the factors associated with the development of ventilator- associated pneumonia (VAP) and examine the etiology, and incidence of VAP. Between November 2007 and June 2008, 148 patients who required mechanical ventilation for longer than 48 hours were evaluated. VAP was observed in 54 patients (36 %). Mechanical ventilator and VAP utilization rates were 0.87 and 22.88 in 1000 ventilator days, respectively. The most common three microorganisms cultured from tracheal aspirates were Pseudomonas aeruginosa (n=19), Acinetobacter species (n=11) and Staphylococcus aureus (n=10). Of the 21 risk factors evaluated, 7 factors identified were independently associated with VAP (p< 0.05): shock, coma (p< 0.0006), antibiotic usage for at least 1 month prior to admission (p< 0.04), nasogastric tube insertion (p< 0.01), invasive procedures such as bronchoscopy, tracheotomy (p< 0.0001), reintubation (p< 0.017), intubation more than 5 days (p< 0.0001), and smoking (p< 0.014). Intensive Care Unit (ICU) clinicians should be aware of the risk factors for VAP to minimize the risk of VAP. Also patient care should be individualized, and procedures like bronchoscopy, and reintubation must be performed and followed up cautiously. Besides these, data about the potential microorganisms and resistance of antibiotics to them will guide the empirical therapy.

Özet

Bu prospektif çalışmada, VAP gelişimi ile ilgili faktörlerinbelirlenmesi ve VAP'ın etyoloji ve insidansının değerlendirilmesiamaçlanmıştır. Kasım 2007 ile Haziran 2008 tarihleriarasında 48 saatten daha uzun sure mekenik ventilator ihtiyacıolan 148 hasta değerlendirilmiştir. Mekanik ventilator kullanımoranı 0,87 ve VAP hızı 1000 ventilatör gününde 22,88 di.Trakeal aspiratlardan en sık izole edilen üç mikroorganizmaPseudomonas aeruginosa (n=19), Acinetobacter species(n=11) ve Staphylococcus aureus (n=10) tu. Değerlendirilen21 risk faktöründen 7'si bağımsız olarak VAP ile ilişkiliydi(p< 0.05): şok, koma (p< 0.0006), başvurudan en az bir ayönce antibiyotik kullanmış olmak (p< 0.04), nazogastrik tüpvarlığı (p< 0.01), bronkoskopi, trakeotomi gibi invaziv prosedürler(p< 0.0001), reentübasyon (p< 0.017), 5 günden uzunsüreli entübasyon (p< 0.0001), sigara kullanımı (p< 0.014).Yoğun Bakım Ünitesi (YBÜ) klinisyenleri VAP riskini azaltmakiçin VAP'a sebep olabilecek risk faktörlerinin farkında olmalı,hasta bakımı kişiselleştirilmeli, bronkoskopi, reentübasyongibi prosedürler dikkatle yapılmalı ve takip edilmelidir.Bunların yanısıra, potansiyel mikroorganizmalar ve antibiyotikdirençleri hakkındaki bilgiler ampirik tedavide kılavuz olacaktır.

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Cite This Article

SAYHAN, H., TİGEN, E., DOGRU, A., SARGIN, F., GURA, M., SAGIROGLU, A. E. (2022). İstanbul'da bir eğitim ve araştırma hastanesi yoğun bakım ünitesinde ventilator ilişkili pnömoninin etyoloji, insidans ve risk faktörleri. Göztepe Tıp Dergisi, Cilt: 27 - Sayı: 3, 94–98. https://ajindex.com/articles/651087

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