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Journals / Sakarya Tıp Dergisi / 2020 / Cilt: 10 - Sayı: 1

Factors Affecting Optimal Continuous Positive Airway Pressure Level in Patients with Obstructive Sleep Apnea Syndrome

Obstrüktif Uyku Apne Sendromlu Hastalarda Optimal Sürekli Pozitif Havayolu Basınç Düzeyini Etkileyen Faktörler

Hülya GÜNBATAR
Havva SAYHAN KAPLAN
Pages
99–106
Publication Date
2020-03-16
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Apnea/hypopnea index (AHI) (r=0.297, p<0.001) and minimal SaO2 (r=-0.264, p<0.004) were significantly correlated with optimal pressure level. 22 patients in the titration failure group had severe AHI overall; 6 patients had REM-related and 2 had position-related OSAS.

📌 3 Key Takeaways

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Objective & Hypothesis:Abstract Objectives: This study aimed to examine factors (BMI, neck circumference, AHI etc.) affecting optimal CPAP levels in patients with obstructive sleep apnea syndrome (OSAS).
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Key Findings & Data:Materials and Methods: A total of 120 patients with OSAS who underwent successful auto-titration for CPAP treatment were included in this study.
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Conclusion & Impact:Apnea/hypopnea index (AHI) (r=0.297, p<0.001) and minimal SaO2 (r=-0.264, p<0.004) were significantly correlated with optimal pressure level. 22 patients in the titration failure group had severe AHI overall; 6 patients had REM-related and 2 had position-related OSAS.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Obstrüktif uyku apne sendromu · Sürekli pozitif havayolu basıncı · apne

Abstract

Abstract Objectives: This study aimed to examine factors (BMI, neck circumference, AHI etc.) affecting optimal CPAP levels in patients with obstructive sleep apnea syndrome (OSAS). Materials and Methods: A total of 120 patients with OSAS who underwent successful auto-titration for CPAP treatment were included in this study. Correlations between the optimal CPAP level and baseline data were analyzed. Results: The mean optimal pressure level in the 120 OSAS patients was 9.11 ± 2.81 cm H2O. The mean optimal pressure levels in the mild, moderate, and severe OSAS groups were 8.01 ± 2.60, 8.32 ± 2.22, and 9.71 ± 3.01 cm H2O, respectively. Apnea/hypopnea index (AHI) (r=0.297, p<0.001) and minimal SaO2 (r=-0.264, p<0.004) were significantly correlated with optimal pressure level. 22 patients in the titration failure group had severe AHI overall; 6 patients had REM-related and 2 had position-related OSAS. Patients in the titration failure group who did not have a specific diagnosis (rapid eye movement (REM) or positional OSAS) had very severe AHI levels (mean AHI of 67.90). Conclusion: According to the correlation tests, AHI and the lowest saturation were the two most important predictors of optimal CPAP level.

Özet

Öz Amaç: Bu çalışmada obstrüktif uyku apne sendromu (OUAS) olan hastalarda optimal CPAP düzeylerini etkileyen faktörlerin (VKİ, boyun çevresi, AHİ vb.) araştırılılması amaçlandı. Gereç ve Yöntem: Bu çalışmaya CPAP tedavisi için başarılı oto titrasyon uygulanan 120 OUAS hastası dahil edildi. Optimal CPAP seviyesi ile başlangıç ​​verileri arasındaki korelasyonlar analiz edildi. Bulgular: 120 OUAS hastasında ortalama optimal basınç seviyesi 9.11 ± 2.81 cm H2O idi. Hafif, orta ve şiddetli OUAS gruplarında ortalama optimal basınç seviyeleri sırasıyla 8.01 ± 2.60, 8.32 ± 2.22 ve 9.71 ± 3.01 cm H2O idi. Apne / hipopne indeksi (AHI) (r = 0.297, p <0.001) ve minimal SaO2 (r = -0.264, p <0.004) optimal basınç seviyesi ile anlamlı korelasyon gösterdi. Titrasyon yetmezliği grubundaki 22 hastada genel olarak ağır AHI vardı; 6 hastada REM ilişkili, 2 hastada pozisyona bağlı OUAS mevcuttu. Titrasyon yetmezliği grubunda, belirli bir tanısı (hızlı göz hareketi (REM) veya pozisyon OUAS) bulunmayan hastalarda çok ciddi AHI düzeyleri vardı (ortalama AHI 67.90 idi). Sonuç: Korelasyon testlerine göre optimal CPAP seviyesinin en önemli iki belirleyicisi AHI ve en düşük saturasyon olarak bulundu.

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Cite This Article

GÜNBATAR, H., KAPLAN, H. S. (2020). Factors Affecting Optimal Continuous Positive Airway Pressure Level in Patients with Obstructive Sleep Apnea Syndrome. Sakarya Tıp Dergisi, Cilt: 10 - Sayı: 1, 99–106. https://ajindex.com/articles/261279

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