Journals / Turkish Neurosurgery / 2012 / Cilt: 22 - Sayı: 4

Travmatik beyin hasarında Transkranial doppler ultrasonografi ile noninvaziv olarak serebral perfüzyon basıncının hesaplanması

Noninvasive estimation of cerebral perfusion pressure with transcranial doppler ultrasonography in traumatic brain injury

Pages
411–415
DOI
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AI Insight
⚡ TL;DR(Too Long; Didn't Read)

AIm: In traumatic brain injury (TBI) patients, to overcome the secondary insults, cerebral perfusion pressure (CPP) oriented therapy is recommended.

📌 3 Key Takeaways

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Objective & Hypothesis:AIm: In traumatic brain injury (TBI) patients, to overcome the secondary insults, cerebral perfusion pressure (CPP) oriented therapy is recommended.
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Key Findings & Data:The formula : ‘MAP x FVd/FVm +14’ was used to estimate CPP noninvasively.
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Conclusion & Impact:As it is recognized that brain perfusion can be assessed with TCD waveforms, noninvasive CPP estimation with MCA flow velocities may help to observe the trends in CPP values.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIm: In traumatic brain injury (TBI) patients, to overcome the secondary insults, cerebral perfusion pressure (CPP) oriented therapy is recommended. The study is assigned to estimate CPP values with middle cerebral artery (MCA) flow velocities measured noninvasively using transcranial Doppler ultrasonography (TCD). MaterIal and Methods: Forty-seven TBI patients were studied. Intracranial pressure (ICP), mean arterial pressure (MAP) and MCA flow velocities of the patients were monitored. Invasive CPP was calculated as the difference between MAP and ICP. The formula : &#8216;MAP x FVd/FVm +14&#8217; was used to estimate CPP noninvasively. Correlation of the noninvasive and invasive values were analysed. Results: The mean values of noninvasive CPP and invasive CPP were 66.10 ± 10.55 mmHg and 65.40 ± 10.03 mmHg respectively. The correlation between noninvasive and invasive CPP measurements was strongly significant (p < 0.001) with a correlation coefficient of r = 0.920. ConclusIon: With ICP monitoring systems, CPP is calculated and the therapy is guided according to these values. As it is recognized that brain perfusion can be assessed with TCD waveforms, noninvasive CPP estimation with MCA flow velocities may help to observe the trends in CPP values.

Özet

AMAÇ: Travmatik beyin hasarında, ikincil hasarın önlenebilmesi için serebral perfüzyon basıncına yönelik tedaviler önerilmektedir. Çalışmamızda, serebral perfüzyon basıncı, noninvaziv olarak transkranial doppler ultrasonografi ile orta serebral arter akım hızının ölçülmesi ile hesaplanmıştır. YÖNTEM ve GEREÇLER: Kırkyedi travmatik beyin hasarlı hasta çalışmaya dahil edilmiştir. İntrakranial basınç, ortalama arteriyel basınç ve orta serebral arter akım hızları izleme alınmıştır. Serebral perfüzyon basıncının invaziv takibi ortalama arteriyel basınç ile intrakranial basınç farkı alınarak bulunmuştur. Serebral perfüzyon basıncının noninvazif olarak bulunmasında ‘MAP x FVd/FVm +14’ formülü kullanılşmıştır. İnvaziv ve noninvaziv değerler arasında ki ilişki analiz edilmiştir. BULGULAR: Noninvaziv ve invaziv serebral perfüzyon basıncı ölçümleri ardışık olarak 66.10 ± 10.55 mmHg ve 65.40 ± 10.03 mmHg’dır. Noninvaziv ve invaziv serebral perfüzyon basıncı ölçümleri arasındaki ilişki belirgin bir şekilde kuvvetlidir (p < 0.001, korelasyon katsayısı r = 0.920). SONUÇ: İntrakranial basınç ölçüm sistemleri ile serebral perfüzyon basıncı hesaplanarak tedavi bu değerlere göre düzenlenmektedir. Tanımlandığı gibi transkranial doppler ultrasonografi ile beyin perfüzyonu hesaplanabilir. Orta serebral arter akım hızları ile serebral perfüzyon basıncının noninvaziv olarak hesaplanması, basınç değişikliklerinin ölçülmesinde yardımcı olabilir.

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Cite This Article

GURA, M., SİLAV, G., IŞIK, N., ELMACI, İ. (2012). Travmatik beyin hasarında Transkranial doppler ultrasonografi ile noninvaziv olarak serebral perfüzyon basıncının hesaplanması. Turkish Neurosurgery, Cilt: 22 - Sayı: 4, 411–415. https://ajindex.com/articles/405013

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