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Journals / Türk Anestezi ve Reanimasyon Dergisi / 2014 / Cilt: 42 - Sayı: 3

Factors affecting tissue oxygenation in erythrocyte transfusions

Eritrosit transfüzyonunda doku oksijenlenmesini etkileyen faktörler

Güçlü AYKUT
Koray YÜRÜK
Can İNCE
Pages
111–116
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, the studies concerning the effects of banked blood and patient characteristics on microcirculation and tissue oxygenation are summarized.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Red blood cell transfusions are used to increase the oxygen-carrying capacity of blood in anemic states.
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Key Findings & Data:But, because of the changes during storage of blood components and the specifics of preparation, erythrocytes may have controversial effects on tissue oxygenation and microcirculation.
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Conclusion & Impact:In this review, the studies concerning the effects of banked blood and patient characteristics on microcirculation and tissue oxygenation are summarized.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Red blood cell transfusions are used to increase the oxygen-carrying capacity of blood in anemic states. But, because of the changes during storage of blood components and the specifics of preparation, erythrocytes may have controversial effects on tissue oxygenation and microcirculation. Also, the patient situation may play a role in the differing responses in oxygenation and microcirculation. In this review, the studies concerning the effects of banked blood and patient characteristics on microcirculation and tissue oxygenation are summarized.

Özet

Eritrosit transfüzyonları anemi durumlarında kanın oksijen taşıma kapasitesini arttırmak için baş vurulan girişimlerdir. Ancak, kanın depolanması sırasında meydana gelen değişiklikler ve hazırlanması ile ilgili özellikler nedeniyle, transfüzyonu yapılan eritrositlerin doku oksijenlenmesine etkileri farklı olabilir. Ayrıca, transfüzyon yapılan hastalara ait özellikler de oksijenlenme ve mikro dolaşımda farklı yanıtların oluşmasına neden olabilir. Bu derlemede, banka kanı ve hastalara ait özelliklerin mikro dolaşım ve doku oksijenlenmesi üzerine etkilerini inceleyen çalışmalar özetlenmiştir.

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Cite This Article

AYKUT, G., YÜRÜK, K., İNCE, C. (2014). Factors affecting tissue oxygenation in erythrocyte transfusions. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 42 - Sayı: 3, 111–116. https://ajindex.com/articles/414119

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References (2)

  1. Hébert PC, Wells G, Tweeddale M, Martin C, Marshall J, Pham B, et al. Does transfusion practice affect mortality in critically ill patients? Transfusion Requirements in Critical Care (TRICC) Investigators and the Canadian Critical Care Trials Group. Am J Respir Crit Care Med 1997; 155: 1618-23. [CrossRef] Almac E, Ince C. The impact of storage on red cell function in blood transfusion. Best Pract Res Clin Anaesthesiol 2007; 21: 195-208. [CrossRef ] Raat NJH, Ince C. Oxygenating the microcirculation: the pers- pective from blood transfusion and blood storage. Vox Sanguin 2007; 93: 12-8. [CrossRef ] Marik PE, Sibbald WJ. Effect of stored-blood transfusion on oxygen delivery in patients with sepsis. JAMA 1993; 269: 3024-9. [CrossRef ] Fernandes CJ Jr, Akamine N, De Marco FV, De Souza JA, La- gudis S, Knobel E. Red blood cell transfusion does not increase oxygen consumption in critically ill septic patients. Crit Care 2001; 5: 362-7. [CrossRef ] Sakr Y, Lobo S, Knuepfer S, Esser E, Bauer M, Settmacher U, et al. Anemia and blood transfusion in a surgical intensive care unit. Crit Care 2010; 14: R92. [CrossRef ] Yuruk K, Almac E, Bezemer R, Goedhart P, de Mol B, Ince C. Blood transfusions recruit the microcirculation during cardiac surgery. Transfusion 2011; 51: 961-7. [CrossRef ] Yuruk K, Bartels SA, Milstein DM, Bezemer R, Biemond BJ, Ince C. Red blood cell transfusions and tissue oxygenation in anemic hematology outpatients. Transfusion 2011; 53: 1346-52.
  2. Ayhan B, Yuruk K, Bakker J, de Mol BAJM, Ince C. Blood transfusions recruit the microcirculation in on-pump cardiac surgery patients, but not in septic patients. Intensive Care Med 2010; 36: Suppl S208: 0489. Starr D (ed.). Blood-an epic history of medicine and commer- ce. New York, Perennial, 2002. Hess JR. Red cell changes during storage. Transfus Apher Sci 2010; 43: 51-9. [CrossRef ] Raat NJ, Verhoeven AJ, Mik EG, Gouwerok CW, Verhaar R, Goedhart PT, et al. The effect of storage time of human red cells on intestinal microcirculatory oxygenation in a rat isovolemic exchange model. Crit Care Med 2005; 33: 39-45. [CrossRef] Bratosin D, Leszczynski S, Sartiaux C, Fontaine O, Descamps J, Huart JJ, et al. Improved storage of erythrocytes by prior leu- kodepletion: flow cytometric evaluation of stored erythrocytes. Cytometry 2001; 46: 351-6. [CrossRef ] Knight JA, Voorhees RP, Martin L, Anstall H. Lipid peroxidati- on in stored red cells. Transfusion 1992; 32: 354-7. [CrossRef ] Messana I, Ferroni L, Misiti F, G